N-(2-巯基丙酰基)甘氨酸

Description

N-(2-mercaptopropionyl)glycine · CAS 1953-02-2 · C5H9NO3S. UNII C5W04GO61S.

Identification

CAS Registry Number	1953-02-2
PubChem CID	5483
Molecular formula	C5H9NO3S
IUPAC name	2-(2-sulfanylpropanoylamino)acetic acid
UNII (FDA)	C5W04GO61S

Computed Descriptors

Molecular Weight	163.20
XLogP3	-0.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	163.03031432
Monoisotopic Mass	163.03031432
Topological Polar Surface Area	67.4
Heavy Atom Count	10
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H302 (100%)

Documented Uses

• Use (kg; approx.) in Germany (2009): >50
• Consumption (g per capita; approx.) in Germany (2009): 0.000611
• Tiopronin is indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria consisting of a urinary cystine concentration greater than 500 mg/day, and who have failed treatment with non-pharmacological measures of increased fluid intake, decreased sodium and protein intake, and urine alkalinization.
• Take at the same time every day. Take each dose at the same time every day.
• Take on an empty stomach. Take tiopronin at least 1 hour before or 2 hours after eating food.
• Mechanisms of Action [MoA] - Cystine Disulfide Reduction

Synonyms

tiopronin; 1953-02-2; N-(2-Mercaptopropionyl)glycine; Thiopronine; Thiola; Tiopronine; 2-(2-sulfanylpropanoylamino)acetic acid; Glycine, N-(2-mercapto-1-oxopropyl)-; Thiolpropionamidoacetic acid; DTXSID4023678; tiopronina; Tioproninum; (2-Mercaptopropionyl)glycine; NSC-760416; C5W04GO61S; THIOLA EC

Frequently Asked Questions

What are the CAS number and molecular formula of N-(2-mercaptopropionyl)glycine?

CAS 1953-02-2; molecular formula C5H9NO3S; molecular weight — g/mol.

What other names is N-(2-mercaptopropionyl)glycine known by?

tiopronin, 1953-02-2, N-(2-Mercaptopropionyl)glycine, Thiopronine, Thiola, Tiopronine.

Is N-(2-mercaptopropionyl)glycine classified as hazardous?

Hazard statements reported: H302.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.