甲基吡啶(CAS 1333-41-1):分子式 C6H7N、分子量 93.13。
| CAS号 | 1333-41-1 |
|---|---|
| 分子式 | C6H7N |
| 分子量 | 93.13 |
| 熔点 | -94 °F (NTP, 1992) |
| 沸点 | 262 to 264 °F at 760 mmHg (NTP, 1992) |
| LogP | 1.1 |
| 应用领域 | Uses: Used as a solvent and chemical intermediate for dyes and resins、[HSDB]、Used as an intermediate (dyes、resins、agrochemicals、and pharmaceuticals)、solvent、and laboratory reagent、[HSDB] Found naturally in coal tar、Used as a solvent and to make dyes and resins、[MSDSonline] Picolines are constituents in cigarette smoke、bone oil、coal tar、and coke oven emissions. [AIHA]、Intermediate in dye and resins industries、solvent.、Organic intermediate for ... rubber chemicals、... laboratory reagent.、Used as a chemical intermediate for the synthesis of: 2-amino-6-methylpyridine、betahistine、bis-acodyl、clopyralid、2-methylpiperidine、perhexiline、... picolinic acid、and、thioridazine.、The primary use of 2-methylpyridine is as a precursor of 2-vinylpyridine. It is also used in a variety of agrochemicals and pharmaceuticals、e.g.、nitrapyrin to prevent loss of ammonia from fertilizers、picloram、a herbicide、and amprolium、a coccidiostat.、Industry Uses: Intermediate、Methods of Manufacturing: ... The reaction of acrylonitrile and acetone、catalyzed by a primary aliphatic amine such as isopropylamine and a weak acid such as benzoic acid、occurs in the liquid phase at 180 °C and 2.2 MPa to give 5-oxohexanenitrile、with 91% selectivity. The acrylonitrile conversion is 86%. Then cyclization and dehydration of the initial product are carried out in the gas phase in the presence of hydrogen over a palladium、nickel、or cobalt- containing catalyst at ca. 240 °C to give 2-methylpyridine in 84% yield.、... Acetonitrile and acetylene react in the presence of cobaltocene as catalyst to give 2-methylpyridine in 76% yield.、Synthesis (40-50% yield) from cyclohexylamine with excess ammonia and zinc chloride at 350 °C.、Prepared from ethylene-mercuric acetate adduct and ammonia water (70% yield).、For more Methods of Manufacturing (Complete) data for 2-METHYLPYRIDINE (8 total)、please visit the HSDB record page.、U.S. Production: 2023: 1、000、000 - <8、500、000 lb、2022: 8、000 - <25、2021: 8、2020: 8、(1972) PROBABLY GREATER THAN 1.82X10+6 GRAMS、(1975) 1.73X10+8 GRAMS、1.89X10+5 kg (1976)、(1989) ca. 8000 t、a、For more U.S. Production (Complete) data for 2-METHYLPYRIDINE (7 total)、General Manufacturing Information: All Other Basic Organic Chemical Manufacturing、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Pyridine、2-methyl-: ACTIVE、methyl-: ACTIVE、Pyridine bases are a constituent of tars. They were isolated from coal tar or coal gas before synthetic manufacturing processes became established. The amounts contained in coal tar and coal gas are small、and the pyridine bases isolated from them are a mixture of many components. Thus、with a few exceptions、isolation of pure pyridine bases was expensive. Today、almost all pyridine bases are produced by synthesis.、Pridine bases |
登记用途:Uses: Used as a solvent and chemical intermediate for dyes and resins、[HSDB]、Used as an intermediate (dyes、resins、agrochemicals、and pharmaceuticals)、solvent、and laboratory reagent、[HSDB] Found naturally in coal tar、Used as a solvent and to make dyes and resins、[MSDSonline] Picolines are constituents in cigarette smoke、bone oil、coal tar、and coke oven emissions. [AIHA]、Intermediate in dye and resins industries、solvent.、Organic intermediate for ... rubber chemicals、... laboratory reagent.、Used as a chemical intermediate for the synthesis of: 2-amino-6-methylpyridine、betahistine、bis-acodyl、clopyralid、2-methylpiperidine、perhexiline、... picolinic acid、and、thioridazine.、The primary use of 2-methylpyridine is as a precursor of 2-vinylpyridine. It is also used in a variety of agrochemicals and pharmaceuticals、e.g.、nitrapyrin to prevent loss of ammonia from fertilizers、picloram、a herbicide、and amprolium、a coccidiostat.、Industry Uses: Intermediate、Methods of Manufacturing: ... The reaction of acrylonitrile and acetone、catalyzed by a primary aliphatic amine such as isopropylamine and a weak acid such as benzoic acid、occurs in the liquid phase at 180 °C and 2.2 MPa to give 5-oxohexanenitrile、with 91% selectivity. The acrylonitrile conversion is 86%. Then cyclization and dehydration of the initial product are carried out in the gas phase in the presence of hydrogen over a palladium、nickel、or cobalt- containing catalyst at ca. 240 °C to give 2-methylpyridine in 84% yield.、... Acetonitrile and acetylene react in the presence of cobaltocene as catalyst to give 2-methylpyridine in 76% yield.、Synthesis (40-50% yield) from cyclohexylamine with excess ammonia and zinc chloride at 350 °C.、Prepared from ethylene-mercuric acetate adduct and ammonia water (70% yield).、For more Methods of Manufacturing (Complete) data for 2-METHYLPYRIDINE (8 total)、please visit the HSDB record page.、U.S. Production: 2023: 1、000、000 - <8、500、000 lb、2022: 8、000 - <25、2021: 8、2020: 8、(1972) PROBABLY GREATER THAN 1.82X10+6 GRAMS、(1975) 1.73X10+8 GRAMS、1.89X10+5 kg (1976)、(1989) ca. 8000 t、a、For more U.S. Production (Complete) data for 2-METHYLPYRIDINE (7 total)、General Manufacturing Information: All Other Basic Organic Chemical Manufacturing、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Pyridine、2-methyl-: ACTIVE、methyl-: ACTIVE、Pyridine bases are a constituent of tars. They were isolated from coal tar or coal gas before synthetic manufacturing processes became established. The amounts contained in coal tar and coal gas are small、and the pyridine bases isolated from them are a mixture of many components. Thus、with a few exceptions、isolation of pure pyridine bases was expensive. Today、almost all pyridine bases are produced by synthesis.、Pridine bases。
甲基吡啶 是一种化工化合物,登记 CAS 号为 1333-41-1,分子式 C6H7N(分子量 93.13)。
登记 CAS 号:1333-41-1
其分子式 C6H7N 由 6 个碳、7 个氢、1 个氮 组成。
别名/同义词:甲基吡啶 · Methylpyridine
甲基吡啶 的 CAS 登记号为 1333-41-1。
分子式 C6H7N,分子量 93.13。
别名/同义词:甲基吡啶、Methylpyridine。
登记用途:Uses: Used as a solvent and chemical intermediate for dyes and resins、[HSDB]、Used as an intermediate (dyes、resins、agrochemicals、and pharmaceuticals)、solvent、and laboratory reagent、[HSDB] Found naturally in coal tar、Used as a solvent and to make dyes and resins、[MSDSonline] Picolines are constituents in cigarette smoke、bone oil、coal tar、and coke oven emissions. [AIHA]、Intermediate in dye and resins industries、solvent.、Organic intermediate for ... rubber chemicals、... laboratory reagent.、Used as a chemical intermediate for the synthesis of: 2-amino-6-methylpyridine、betahistine、bis-acodyl、clopyralid、2-methylpiperidine、perhexiline、... picolinic acid、and、thioridazine.、The primary use of 2-methylpyridine is as a precursor of 2-vinylpyridine. It is also used in a variety of agrochemicals and pharmaceuticals、e.g.、nitrapyrin to prevent loss of ammonia from fertilizers、picloram、a herbicide、and amprolium、a coccidiostat.、Industry Uses: Intermediate、Methods of Manufacturing: ... The reaction of acrylonitrile and acetone、catalyzed by a primary aliphatic amine such as isopropylamine and a weak acid such as benzoic acid、occurs in the liquid phase at 180 °C and 2.2 MPa to give 5-oxohexanenitrile、with 91% selectivity. The acrylonitrile conversion is 86%. Then cyclization and dehydration of the initial product are carried out in the gas phase in the presence of hydrogen over a palladium、nickel、or cobalt- containing catalyst at ca. 240 °C to give 2-methylpyridine in 84% yield.、... Acetonitrile and acetylene react in the presence of cobaltocene as catalyst to give 2-methylpyridine in 76% yield.、Synthesis (40-50% yield) from cyclohexylamine with excess ammonia and zinc chloride at 350 °C.、Prepared from ethylene-mercuric acetate adduct and ammonia water (70% yield).、For more Methods of Manufacturing (Complete) data for 2-METHYLPYRIDINE (8 total)、please visit the HSDB record page.、U.S. Production: 2023: 1、000、000 - <8、500、000 lb、2022: 8、000 - <25、2021: 8、2020: 8、(1972) PROBABLY GREATER THAN 1.82X10+6 GRAMS、(1975) 1.73X10+8 GRAMS、1.89X10+5 kg (1976)、(1989) ca. 8000 t、a、For more U.S. Production (Complete) data for 2-METHYLPYRIDINE (7 total)、General Manufacturing Information: All Other Basic Organic Chemical Manufacturing、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Pyridine、2-methyl-: ACTIVE、methyl-: ACTIVE、Pyridine bases are a constituent of tars. They were isolated from coal tar or coal gas before synthetic manufacturing processes became established. The amounts contained in coal tar and coal gas are small、and the pyridine bases isolated from them are a mixture of many components. Thus、with a few exceptions、isolation of pure pyridine bases was expensive. Today、almost all pyridine bases are produced by synthesis.、Pridine bases。
甲基吡啶(CAS 1333-41-1)的独立参考数据,整理自公开化学数据库。
| CAS 号 | 1333-41-1 |
|---|---|
| PubChem CID | 7975 |
| 分子式 | C6H7N |
| IUPAC 名称 | 2-methylpyridine |
| UNII(FDA) | 3716Q16Q6A |
| Molecular Weight | 93.13 |
|---|---|
| XLogP3 | 1.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 93.057849228 |
| Monoisotopic Mass | 93.057849228 |
| Topological Polar Surface Area | 12.9 |
| Heavy Atom Count | 7 |
| Boiling Point | 262 to 264 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 129.4 °C |
| Boiling Point | 128-129 °C |
| Boiling Point | 129 °C @760 [mm Hg] |
| Melting Point | -94 °F (NTP, 1992) |
| Melting Point | -66.65 °C |
| Melting Point | -70 °C |
| Flash Point | 97 °F (NTP, 1992) |
| Flash Point | 26 °C |
| Flash Point | 102 °F (39 °C)(Open cup) |
2-METHYLPYRIDINE; 2-Picoline; 109-06-8; alpha-Picoline; o-Picoline; Pyridine, 2-methyl-; alpha-Methylpyridine; o-Methylpyridine; PICOLINE, ALPHA; DTXSID9021899; NSC-3409; 3716Q16Q6A; DTXCID001899; CHEBI:50415; RefChem:88380; 203-643-7
| 法规与食品接触 | EU Flavoring substances Flavoring Agents |
|---|---|
| GHS 通报统计 | 2.7% (11 / 409) |
| GHS 通报统计 | 2.7% (11 / 409) |
|---|---|
| 已通报的危害声明 | H226, H302, H312, H319, H332, H335, H311 (53.5%), H314 (44.3%) |
甲基吡啶 · CAS 1333-41-1 · C6H7N. UNII 3716Q16Q6A. Boiling Point: 262 to 264 °F at 760 mmHg (NTP, 1992); Boiling Point: 129.4 °C; Boiling Point: 128-129 °C.
数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。
English page: Methylpyridine