metaraminol (CAS 54-49-9) — formula C9H13NO2, molecular weight 167.20; category organic chemicals.
| CAS Number | 54-49-9 |
|---|---|
| Molecular Formula | C9H13NO2 |
| Molecular Weight | 167.20 |
| Melting Point | 107.5 |
| Boiling Point | 218 |
| LogP | -0.27 |
| Applications | Uses: Therap cat: Adrenergic, MEDICATION (VET), ...for prevention and treatment of the acute hypertensive state occurring with spinal anesthesia., Bitartrate, A sympathomimetic drug with prominent direct effects on vascular alpha-adrenergic receptors. Metaraminol is also an indirectly acting agent that stimulates the release of norepinephrine. ...had been used in the treatment of hypotensive states or to relieve attacks of paroxysmal atrial tachycardia, particularly those associated with hypotension., Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: from m-hydroxyisonitrosopropiophenone., ...from l-m-hydroxyphenylacetylcarbinol., M-HYDROXYBENZALDEHYDE IS FERMENTED WITH YEAST...TO YIELD M-(HYDROXYPHENYL) ACETYLCARBINOL..., &, CONDENSATION..., WITH BENZYLAMINE IS, FOLLOWED BY HYDROGENATION OF C=N LINKAGE & REDUCTIVE CLEAVAGE... METARAMINOL... IS PURIFIED &...CONVERTED TO BITARTRATE BY DISSOLVING IN ETHANOL & REACTING...WITH...TARTARIC ACID., Formulations, Preparations: METARAMINOL BITARTRATE USP (ARAMINE), IS AVAILABLE IN 1-ML AMPULS & 10-ML VIALS AS A STERILE SOLN (10 MG, ML) FOR INTRAMUSCULAR INJECTION, USUALLY IN DOSE OF 5-10 MG, OR, AFTER SUITABLE DILUTION, FOR IV INFUSION. RATE OF ADMIN IS REGULATED ACCORDING TO THE INDIVIDUAL'S RESPONSE TO THE DRUG., BITARTRATE, General Manufacturing Information: VET: MAY DISCOLOR POLYETHYLENE TUBING OR DEVICES. |
| Category | Organic Chemicals |
Documented applications: Uses: Therap cat: Adrenergic, MEDICATION (VET), ...for prevention and treatment of the acute hypertensive state occurring with spinal anesthesia., Bitartrate, A sympathomimetic drug with prominent direct effects on vascular alpha-adrenergic receptors. Metaraminol is also an indirectly acting agent that stimulates the release of norepinephrine. ...had been used in the treatment of hypotensive states or to relieve attacks of paroxysmal atrial tachycardia, particularly those associated with hypotension., Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: from m-hydroxyisonitrosopropiophenone., ...from l-m-hydroxyphenylacetylcarbinol., M-HYDROXYBENZALDEHYDE IS FERMENTED WITH YEAST...TO YIELD M-(HYDROXYPHENYL) ACETYLCARBINOL..., &, CONDENSATION..., WITH BENZYLAMINE IS, FOLLOWED BY HYDROGENATION OF C=N LINKAGE & REDUCTIVE CLEAVAGE... METARAMINOL... IS PURIFIED &...CONVERTED TO BITARTRATE BY DISSOLVING IN ETHANOL & REACTING...WITH...TARTARIC ACID., Formulations, Preparations: METARAMINOL BITARTRATE USP (ARAMINE), IS AVAILABLE IN 1-ML AMPULS & 10-ML VIALS AS A STERILE SOLN (10 MG, ML) FOR INTRAMUSCULAR INJECTION, USUALLY IN DOSE OF 5-10 MG, OR, AFTER SUITABLE DILUTION, FOR IV INFUSION. RATE OF ADMIN IS REGULATED ACCORDING TO THE INDIVIDUAL'S RESPONSE TO THE DRUG., BITARTRATE, General Manufacturing Information: VET: MAY DISCOLOR POLYETHYLENE TUBING OR DEVICES..
metaraminol is a carbon-based organic compound with CAS registry number 54-49-9 and molecular formula C9H13NO2 (molecular weight 167.20), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 54-49-9
Its molecular formula C9H13NO2 comprises 9 C, 13 H, 1 N, 2 O atoms.
Also known as: metaraminol · 间羟胺
Category: organic chemicals
The CAS registry number of metaraminol is 54-49-9.
Molecular formula C9H13NO2, molecular weight 167.20.
It is also registered under: metaraminol, 间羟胺.
Recorded applications: Uses: Therap cat: Adrenergic, MEDICATION (VET), ...for prevention and treatment of the acute hypertensive state occurring with spinal anesthesia., Bitartrate, A sympathomimetic drug with prominent direct effects on vascular alpha-adrenergic receptors. Metaraminol is also an indirectly acting agent that stimulates the release of norepinephrine. ...had been used in the treatment of hypotensive states or to relieve attacks of paroxysmal atrial tachycardia, particularly those associated with hypotension., Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: from m-hydroxyisonitrosopropiophenone., ...from l-m-hydroxyphenylacetylcarbinol., M-HYDROXYBENZALDEHYDE IS FERMENTED WITH YEAST...TO YIELD M-(HYDROXYPHENYL) ACETYLCARBINOL..., &, CONDENSATION..., WITH BENZYLAMINE IS, FOLLOWED BY HYDROGENATION OF C=N LINKAGE & REDUCTIVE CLEAVAGE... METARAMINOL... IS PURIFIED &...CONVERTED TO BITARTRATE BY DISSOLVING IN ETHANOL & REACTING...WITH...TARTARIC ACID., Formulations, Preparations: METARAMINOL BITARTRATE USP (ARAMINE), IS AVAILABLE IN 1-ML AMPULS & 10-ML VIALS AS A STERILE SOLN (10 MG, ML) FOR INTRAMUSCULAR INJECTION, USUALLY IN DOSE OF 5-10 MG, OR, AFTER SUITABLE DILUTION, FOR IV INFUSION. RATE OF ADMIN IS REGULATED ACCORDING TO THE INDIVIDUAL'S RESPONSE TO THE DRUG., BITARTRATE, General Manufacturing Information: VET: MAY DISCOLOR POLYETHYLENE TUBING OR DEVICES..
Category: Organic Chemicals.
Independent reference data for metaraminol (CAS 54-49-9), compiled from public chemistry databases.
| CAS Registry Number | 54-49-9 |
|---|---|
| PubChem CID | 5906 |
| Molecular formula | C9H13NO2 |
| IUPAC name | 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol |
| UNII (FDA) | 818U2PZ2EH |
| Molecular Weight | 167.20 |
|---|---|
| XLogP3 | -0.4 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 167.094628657 |
| Monoisotopic Mass | 167.094628657 |
| Topological Polar Surface Area | 66.5 |
| Heavy Atom Count | 12 |
| Boiling Point | 218 |
|---|---|
| Melting Point | 107.5 |
| Melting Point | 107.5 °C |
| Solubility | 1000 |
| Solubility | 1.28e+01 g/L |
| LogP | -0.27 |
| LogP | log Kow= -0.27 |
| LogP | 0.6 |
| Dissociation Constants | 8.79 |
metaraminol; L-Metaraminol; Metaradrine; Hydroxynorephedrine; m-Hydroxypropadrine; 1-Metaraminol; Pressorol; m-Hydroxy norephedrine; (-)-Erythro-metaraminol; Icoral B; 54-49-9; m-Hydroxyphenylpropanolamine; Metaraminolum; 3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol; 3-Hydroxyphenylisopropanolamine; 1-(m-Hydroxyphenyl)-2-amino-1-propanol
metaraminol · CAS 54-49-9 · C9H13NO2. UNII 818U2PZ2EH. Boiling Point: 218; Melting Point: 107.5; Melting Point: 107.5 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 间羟胺