甲氟喹

CAS 53230-10-7C17H16F6N2OMW 378.31

甲氟喹（CAS 53230-10-7）：分子式 C17H16F6N2O、分子量 378.31。

产品概览

CAS号	53230-10-7
分子式	C17H16F6N2O
分子量	378.31
熔点	250-254
沸点	415.7±40.0 °C
LogP	3.9
应用领域	Uses: Antimalarials、MEDICATION、Use (kg、approx.) in Germany (2009): >100、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Calculated removal (%): 55.5、Methods of Manufacturing: Preparation of erythro-form: G. Grethe、T. Mitt、German patent 2806909、H. Bomches、B. Hardegger、United States of America patent 4507482 (1978、1985 both to Hoffman-La Roche).、Formulations、Preparations: Fansimef is a combination of mefloquine with Fansidar (pyrimethamine and sulfadoxine)、Mefloquine hydrochloride、Table: Mefloquine Hydrochloride Preparations [Table#6364]、General Manufacturing Information: A 250 mg tablet is equivalent to 228 mg of mefloquine base. The product available in Canada and other countries is 250 mg of mefloquine base、equivalent to 274 mg of mefloquine hydrochloride.

应用领域

登记用途：Uses: Antimalarials、MEDICATION、Use (kg、approx.) in Germany (2009): >100、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Calculated removal (%): 55.5、Methods of Manufacturing: Preparation of erythro-form: G. Grethe、T. Mitt、German patent 2806909、H. Bomches、B. Hardegger、United States of America patent 4507482 (1978、1985 both to Hoffman-La Roche).、Formulations、Preparations: Fansimef is a combination of mefloquine with Fansidar (pyrimethamine and sulfadoxine)、Mefloquine hydrochloride、Table: Mefloquine Hydrochloride Preparations [Table#6364]、General Manufacturing Information: A 250 mg tablet is equivalent to 228 mg of mefloquine base. The product available in Canada and other countries is 250 mg of mefloquine base、equivalent to 274 mg of mefloquine hydrochloride.。

技术档案

这个产品是什么

甲氟喹是一种化工化合物，登记 CAS 号为 53230-10-7，分子式 C17H16F6N2O（分子量 378.31）。

识别信息

登记 CAS 号：53230-10-7

其分子式 C17H16F6N2O 由 17 个碳、16 个氢、6 个氟、2 个氮、1 个氧组成。

别名/同义词：甲氟喹 · Mefloquine

常见问题

甲氟喹的 CAS 号是多少？

甲氟喹的 CAS 登记号为 53230-10-7。

甲氟喹的分子式与分子量是多少？

分子式 C17H16F6N2O，分子量 378.31。

甲氟喹还有哪些别名？

别名/同义词：甲氟喹、Mefloquine。

甲氟喹的登记用途是什么？

PubChem 公开数据

甲氟喹（CAS 53230-10-7）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number	53230-10-7
PubChem CID	4046
Molecular formula	C17H16F6N2O
IUPAC name	[2,8-bis(trifluoromethyl)quinolin-4-yl]-piperidin-2-ylmethanol
UNII (FDA)	TML814419R

计算分子描述符

Molecular Weight	378.31
XLogP3	3.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	2
Exact Mass	378.11668211
Monoisotopic Mass	378.11668211
Topological Polar Surface Area	45.2
Heavy Atom Count	26

在册的理化数值

Boiling Point	415.7±40.0 °C
Melting Point	250-254
Melting Point	174-176 °C
Solubility	1.806
Solubility	3.80e-02 g/L
LogP	3.9
Dissociation Constants	8.6

在册的记载用途

同义词与商品名

mefloquine; Mefloquina; 53230-10-7; GNF-Pf-5544; Racemic mefloquine; [2,8-bis(trifluoromethyl)quinolin-4-yl]-piperidin-2-ylmethanol; Mefloquinum; Ro-215998; NSC-758233; Ro 21-5998; WR 142,490; DTXSID4037168; Mephloquine; (2,8-bis(trifluoromethyl)quinolin-4-yl)-piperidin-2-ylmethanol; RefChem:56342; CHEBI:63609

GHS 危害分类

Reported hazard statements	H302

H302: Harmful if swallowed [Warning Acute toxicity, oral]

P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)

公开数据库对它的描述

Mefloquine · CAS 53230-10-7 · C17H16F6N2O. UNII TML814419R. Boiling Point: 415.7±40.0 °C; Melting Point: 250-254; Melting Point: 174-176 °C.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。

甲氟喹