loxapine (CAS 1977-10-2) — formula C18H18ClN3O, molecular weight 327.8; category organic chemicals.
| CAS Number | 1977-10-2 |
|---|---|
| Molecular Formula | C18H18ClN3O |
| Molecular Weight | 327.8 |
| Melting Point | 109-111 °C |
| LogP | 3.6 |
| Applications | Uses: MEDICATION, For the management of the manifestations of psychotic disorders such as schizophrenia, Use Classification: Pharmaceuticals, Methods of Manufacturing: Netherlands patent application 6, 406, 089 corresponds to Schmutz et al, US patent 3, 546, 226 (1964, 1970 both to Wander), Eidem, Helv Chim Acta 50, 245 (1967), Coppola, 412, 193 (1968 to American Cyanamid)., Formulations, Preparations: LOXITANE (LEDERLE). ORAL: CAPSULES 10, 25, & 50 MG (EXPRESSED IN TERMS OF BASE)., SUCCINATE |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, For the management of the manifestations of psychotic disorders such as schizophrenia, Use Classification: Pharmaceuticals, Methods of Manufacturing: Netherlands patent application 6, 406, 089 corresponds to Schmutz et al, US patent 3, 546, 226 (1964, 1970 both to Wander), Eidem, Helv Chim Acta 50, 245 (1967), Coppola, 412, 193 (1968 to American Cyanamid)., Formulations, Preparations: LOXITANE (LEDERLE). ORAL: CAPSULES 10, 25, & 50 MG (EXPRESSED IN TERMS OF BASE)., SUCCINATE.
loxapine is a carbon-based organic compound with CAS registry number 1977-10-2 and molecular formula C18H18ClN3O (molecular weight 327.8), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 1977-10-2
Its molecular formula C18H18ClN3O comprises 18 C, 18 H, 1 Cl, 3 N, 1 O atoms.
Also known as: loxapine · 洛沙平
Category: organic chemicals
The CAS registry number of loxapine is 1977-10-2.
Molecular formula C18H18ClN3O, molecular weight 327.8.
It is also registered under: loxapine, 洛沙平.
Recorded applications: Uses: MEDICATION, For the management of the manifestations of psychotic disorders such as schizophrenia, Use Classification: Pharmaceuticals, Methods of Manufacturing: Netherlands patent application 6, 406, 089 corresponds to Schmutz et al, US patent 3, 546, 226 (1964, 1970 both to Wander), Eidem, Helv Chim Acta 50, 245 (1967), Coppola, 412, 193 (1968 to American Cyanamid)., Formulations, Preparations: LOXITANE (LEDERLE). ORAL: CAPSULES 10, 25, & 50 MG (EXPRESSED IN TERMS OF BASE)., SUCCINATE.
Category: Organic Chemicals.
Independent reference data for loxapine (CAS 1977-10-2), compiled from public chemistry databases.
| CAS Registry Number | 1977-10-2 |
|---|---|
| PubChem CID | 3964 |
| Molecular formula | C18H18ClN3O |
| IUPAC name | 8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepine |
| UNII (FDA) | LER583670J |
| Molecular Weight | 327.8 |
|---|---|
| XLogP3 | 3.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 327.1138399 |
| Monoisotopic Mass | 327.1138399 |
| Topological Polar Surface Area | 28.1 |
| Heavy Atom Count | 23 |
| Melting Point | 109-111 °C |
|---|---|
| Melting Point | 109-110 °C |
| Melting Point | 109 - 110 °C |
| Solubility | 1.03e-01 g/L |
| LogP | 3.6 |
| LogP | 3.86 |
| Dissociation Constants | 7.48 |
| Dissociation Constants | 7.5 |
loxapine; 1977-10-2; Cloxazepine; Oxilapine; Loxapin; Adasuve; Loxapina; Loxapinum; Hydrofluoride 3170; CL-62362; SUM 3170; SUM-3170; HF 3170; LW 3170; Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-; CL 62362
| Reported hazard statements | H301 (100%) |
|---|
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)
loxapine · CAS 1977-10-2 · C18H18ClN3O. UNII LER583670J. Melting Point: 109-111 °C; Melting Point: 109-110 °C; Melting Point: 109 - 110 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 洛沙平