Lopinavir (CAS 192725-17-0) — formula C37H48N4O5, molecular weight 628.8; category organic chemicals.
| CAS Number | 192725-17-0 |
|---|---|
| Molecular Formula | C37H48N4O5 |
| Molecular Weight | 628.8 |
| Melting Point | 124-127 °C |
| LogP | 5.9 |
| Applications | Uses: Anti-HIV Agents, HIV Protease Inhibitors, MEDICATION, Use (kg) in Switzerland (2009): >250, Use (kg, approx.) in Germany (2009): >1000, Use (kg) in USA (2002): 9360, Consumption (g per capita) in Switzerland (2009): 0.032, Consumption (g per capita, approx.) in Germany (2009): 0.012, Consumption (g per capita) in the USA (2002): 0.033, Excretion rate: 0.03, Calculated removal (%): 91.9, Formulations, Preparations: Table: Lopinavir and Ritonavir Preparations [Table#8101] |
| Category | Organic Chemicals |
Documented applications: Uses: Anti-HIV Agents, HIV Protease Inhibitors, MEDICATION, Use (kg) in Switzerland (2009): >250, Use (kg, approx.) in Germany (2009): >1000, Use (kg) in USA (2002): 9360, Consumption (g per capita) in Switzerland (2009): 0.032, Consumption (g per capita, approx.) in Germany (2009): 0.012, Consumption (g per capita) in the USA (2002): 0.033, Excretion rate: 0.03, Calculated removal (%): 91.9, Formulations, Preparations: Table: Lopinavir and Ritonavir Preparations [Table#8101].
Lopinavir is a carbon-based organic compound with CAS registry number 192725-17-0 and molecular formula C37H48N4O5 (molecular weight 628.8), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 192725-17-0
Its molecular formula C37H48N4O5 comprises 37 C, 48 H, 4 N, 5 O atoms.
Also known as: Lopinavir · 洛匹那韦
Category: organic chemicals
The CAS registry number of Lopinavir is 192725-17-0.
Molecular formula C37H48N4O5, molecular weight 628.8.
It is also registered under: Lopinavir, 洛匹那韦.
Recorded applications: Uses: Anti-HIV Agents, HIV Protease Inhibitors, MEDICATION, Use (kg) in Switzerland (2009): >250, Use (kg, approx.) in Germany (2009): >1000, Use (kg) in USA (2002): 9360, Consumption (g per capita) in Switzerland (2009): 0.032, Consumption (g per capita, approx.) in Germany (2009): 0.012, Consumption (g per capita) in the USA (2002): 0.033, Excretion rate: 0.03, Calculated removal (%): 91.9, Formulations, Preparations: Table: Lopinavir and Ritonavir Preparations [Table#8101].
Category: Organic Chemicals.
Independent reference data for Lopinavir (CAS 192725-17-0), compiled from public chemistry databases.
| CAS Registry Number | 192725-17-0 |
|---|---|
| PubChem CID | 92727 |
| Molecular formula | C37H48N4O5 |
| IUPAC name | (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide |
| UNII (FDA) | 2494G1JF75 |
| Molecular Weight | 628.8 |
|---|---|
| XLogP3 | 5.9 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 15 |
| Exact Mass | 628.36247064 |
| Monoisotopic Mass | 628.36247064 |
| Topological Polar Surface Area | 120 |
| Heavy Atom Count | 46 |
| Melting Point | 124-127 °C |
|---|---|
| Solubility | 1.92e-03 g/L |
Lopinavir; 192725-17-0; ABT-378; Aluviran; Koletra; A 157378.0; A-157378.0; Lopinavirum; DTXSID8046456; CHEBI:31781; A-157378-0; ABT378; Lopinavir, (s-(2s,4s,5s))-; 2494G1JF75; DTXCID6026456; RefChem:5960
| GHS notification summary | 1.6% (1 / 61) |
|---|
| GHS notification summary | 1.6% (1 / 61) |
|---|---|
| Reported hazard statements | H315 (88.5%), H319 (88.5%), H335 (88.5%), H373 (95.1%) |
This chemical does not meet GHS hazard criteria for 1.6% (1 of 61) of reports.
H315 (88.5%): Causes skin irritation [Warning Skin corrosion/irritation]
Lopinavir · CAS 192725-17-0 · C37H48N4O5. UNII 2494G1JF75. Melting Point: 124-127 °C; Solubility: 1.92e-03 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 洛匹那韦