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lofepramine hydrochloride

CAS 26786-32-3C26H28Cl2N2OMW 455.4

lofepramine hydrochloride (CAS 26786-32-3) — formula C26H28Cl2N2O, molecular weight 455.4; category organic chemicals.

Product Overview

CAS Number26786-32-3
Molecular FormulaC26H28Cl2N2O
Molecular Weight455.4
CategoryOrganic Chemicals

Technical Profile

What this product is

lofepramine hydrochloride is a carbon-based organic compound with CAS registry number 26786-32-3 and molecular formula C26H28Cl2N2O (molecular weight 455.4), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 26786-32-3

Its molecular formula C26H28Cl2N2O comprises 26 C, 28 H, 2 Cl, 2 N, 1 O atoms.

Also known as: lofepramine hydrochloride · 盐酸洛非帕明

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of lofepramine hydrochloride?

The CAS registry number of lofepramine hydrochloride is 26786-32-3.

What is the molecular formula and molecular weight of lofepramine hydrochloride?

Molecular formula C26H28Cl2N2O, molecular weight 455.4.

What other names is lofepramine hydrochloride known by?

It is also registered under: lofepramine hydrochloride, 盐酸洛非帕明.

Which category does lofepramine hydrochloride belong to?

Category: Organic Chemicals.

PubChem Public Data

Independent reference data for lofepramine hydrochloride (CAS 26786-32-3), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number26786-32-3
PubChem CID33611
Molecular formulaC26H28Cl2N2O
IUPAC name1-(4-chlorophenyl)-2-[3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)propyl-methylamino]ethanone;hydrochloride
UNII (FDA)Z24K96F991

Computed descriptors

Molecular Weight455.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count7
Exact Mass454.1578689
Monoisotopic Mass454.1578689
Topological Polar Surface Area23.6
Heavy Atom Count31

Documented uses on record

  • Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.

Synonyms and trade names

lofepramine hydrochloride; 26786-32-3; Lofepramine HCl; Clopepramine hydrochloride; Amplit; DTXSID9047833; WHR-2908A; 4'-Chloro-2-((3-(10,11-dihydro-5H-dibenz(b,f)azepin-5-yl)propyl)methylamino)acetophenone monohydrochloride; Z24K96F991; DTXCID5027809; CHEBI:31780; RefChem:800018; Hydrochloride, Lofepramine; 248-002-2; 4'-Chloro-2-((3-(10,11-Dihydro-5H-Dibenz(b, f)azepin-5-yl)Propyl)Methylamino)acetophenone Monohydrochloride; LOFEPRAMINEHYDROCHLORIDE

GHS hazard classification

Reported hazard statementsH302 (95%), H335 (95%), H413 (95%)

H302 (95%): Harmful if swallowed [Warning Acute toxicity, oral]

H335 (95%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

What the public record says

lofepramine hydrochloride · CAS 26786-32-3 · C26H28Cl2N2O. UNII Z24K96F991.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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