lisinopril (CAS 76547-98-3) — formula C21H31N3O5, molecular weight 405.5; category organic chemicals.
| CAS Number | 76547-98-3 |
|---|---|
| Molecular Formula | C21H31N3O5 |
| Molecular Weight | 405.5 |
| Melting Point | 148 |
| LogP | -1.01 |
| Applications | Uses: MEDICATION (VET), MEDICATION, Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Cardiotonic Agents, Use (kg, approx.) in Germany (2009): >5000, Use (kg) in USA (2002): 11300, Consumption (g per capita, approx.) in Germany (2009): 0.0611, Consumption (g per capita) in the USA (2002): 0.0401, Excretion rate: 1, Calculated removal (%): 75.1, Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: A.A. Patchett et al., European Patent Office patent 12401, E.E. Harris et al., United States of America patent 4374829 (1980, 1983 both to Merck & Co.)., Formulations, Preparations: Table: Lisinopril Preparations [Table#6361], Table: Lisinopril Combinations Preparations [Table#6362] |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION (VET), MEDICATION, Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Cardiotonic Agents, Use (kg, approx.) in Germany (2009): >5000, Use (kg) in USA (2002): 11300, Consumption (g per capita, approx.) in Germany (2009): 0.0611, Consumption (g per capita) in the USA (2002): 0.0401, Excretion rate: 1, Calculated removal (%): 75.1, Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: A.A. Patchett et al., European Patent Office patent 12401, E.E. Harris et al., United States of America patent 4374829 (1980, 1983 both to Merck & Co.)., Formulations, Preparations: Table: Lisinopril Preparations [Table#6361], Table: Lisinopril Combinations Preparations [Table#6362].
lisinopril is a carbon-based organic compound with CAS registry number 76547-98-3 and molecular formula C21H31N3O5 (molecular weight 405.5), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 76547-98-3
Its molecular formula C21H31N3O5 comprises 21 C, 31 H, 3 N, 5 O atoms.
Also known as: lisinopril · 赖诺普利
Category: organic chemicals
The CAS registry number of lisinopril is 76547-98-3.
Molecular formula C21H31N3O5, molecular weight 405.5.
It is also registered under: lisinopril, 赖诺普利.
Recorded applications: Uses: MEDICATION (VET), MEDICATION, Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Cardiotonic Agents, Use (kg, approx.) in Germany (2009): >5000, Use (kg) in USA (2002): 11300, Consumption (g per capita, approx.) in Germany (2009): 0.0611, Consumption (g per capita) in the USA (2002): 0.0401, Excretion rate: 1, Calculated removal (%): 75.1, Use Classification: Pharmaceuticals, Methods of Manufacturing: Prepn: A.A. Patchett et al., European Patent Office patent 12401, E.E. Harris et al., United States of America patent 4374829 (1980, 1983 both to Merck & Co.)., Formulations, Preparations: Table: Lisinopril Preparations [Table#6361], Table: Lisinopril Combinations Preparations [Table#6362].
Category: Organic Chemicals.
Independent reference data for lisinopril (CAS 76547-98-3), compiled from public chemistry databases.
| CAS Registry Number | 76547-98-3 |
|---|---|
| PubChem CID | 5362119 |
| Molecular formula | C21H31N3O5 |
| IUPAC name | (2S)-1-[(2S)-6-amino-2-[[(1S)-1-carboxy-3-phenylpropyl]amino]hexanoyl]pyrrolidine-2-carboxylic acid |
| UNII (FDA) | 7Q3P4BS2FD |
| Molecular Weight | 405.5 |
|---|---|
| XLogP3 | -2.9 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 12 |
| Exact Mass | 405.22637110 |
| Monoisotopic Mass | 405.22637110 |
| Topological Polar Surface Area | 133 |
| Heavy Atom Count | 29 |
| Melting Point | 148 |
|---|---|
| Solubility | 97000 |
| Solubility | 97 mg/mL |
| LogP | -1.01 |
| LogP | log Kow = -1.22 |
| Dissociation Constants | 2.5 (at 25 °C) |
lisinopril; 76547-98-3; Prinivil; Zestril; Lisinopril anhydrous; Lysinopril; Carace; Novatec; Lisinoprilum; Lisinoprilum [Latin]; Qbrelis; 7Q3P4BS2FD; MK-521; [N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE; N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline; N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
| GHS notification summary | 14.3% (1 / 7) |
|---|
| GHS notification summary | 14.3% (1 / 7) |
|---|---|
| Reported hazard statements | H315 (28.6%), H319 (71.4%), H360 (42.9%), H361 (28.6%), H362 (28.6%), H373 (42.9%) |
This chemical does not meet GHS hazard criteria for 14.3% (1 of 7) of reports.
H315 (28.6%): Causes skin irritation [Warning Skin corrosion/irritation]
lisinopril · CAS 76547-98-3 · C21H31N3O5. UNII 7Q3P4BS2FD. Melting Point: 148; Solubility: 97000; Solubility: 97 mg/mL.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 赖诺普利