Linagliptin (CAS 668270-12-0) — formula C25H28N8O2, molecular weight 472.5; category organic chemicals.
| CAS Number | 668270-12-0 |
|---|---|
| Molecular Formula | C25H28N8O2 |
| Molecular Weight | 472.5 |
| Melting Point | 190-196 |
| LogP | 1.9 |
| Applications | Uses: MEDICATION, Hypoglycemic Agents, Formulations, Preparations: Jentadueto is a combination of linagliptin and metformin hydrochloride. Jentadueto tablets are available in the following dosage forms and strengths: 2.5 mg linagliptin, 500 mg metformin hydrochloride, 2.5 mg linagliptin, 850 mg metformin hydrochloride tablets, 1000 mg metformin hydrochloride tablets., Oral: Tablet, film coated: 5 mg, Tradjenta (Boehringer Ingelheim, comarketed by Lilly) |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, Hypoglycemic Agents, Formulations, Preparations: Jentadueto is a combination of linagliptin and metformin hydrochloride. Jentadueto tablets are available in the following dosage forms and strengths: 2.5 mg linagliptin, 500 mg metformin hydrochloride, 2.5 mg linagliptin, 850 mg metformin hydrochloride tablets, 1000 mg metformin hydrochloride tablets., Oral: Tablet, film coated: 5 mg, Tradjenta (Boehringer Ingelheim, comarketed by Lilly).
Linagliptin is a carbon-based organic compound with CAS registry number 668270-12-0 and molecular formula C25H28N8O2 (molecular weight 472.5), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 668270-12-0
Its molecular formula C25H28N8O2 comprises 25 C, 28 H, 8 N, 2 O atoms.
Also known as: Linagliptin · 利格列汀
Category: organic chemicals
The CAS registry number of Linagliptin is 668270-12-0.
Molecular formula C25H28N8O2, molecular weight 472.5.
It is also registered under: Linagliptin, 利格列汀.
Recorded applications: Uses: MEDICATION, Hypoglycemic Agents, Formulations, Preparations: Jentadueto is a combination of linagliptin and metformin hydrochloride. Jentadueto tablets are available in the following dosage forms and strengths: 2.5 mg linagliptin, 500 mg metformin hydrochloride, 2.5 mg linagliptin, 850 mg metformin hydrochloride tablets, 1000 mg metformin hydrochloride tablets., Oral: Tablet, film coated: 5 mg, Tradjenta (Boehringer Ingelheim, comarketed by Lilly).
Category: Organic Chemicals.
Independent reference data for Linagliptin (CAS 668270-12-0), compiled from public chemistry databases.
| CAS Registry Number | 668270-12-0 |
|---|---|
| PubChem CID | 10096344 |
| Molecular formula | C25H28N8O2 |
| IUPAC name | 8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione |
| UNII (FDA) | 3X29ZEJ4R2 |
| Molecular Weight | 472.5 |
|---|---|
| XLogP3 | 1.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 4 |
| Exact Mass | 472.23352217 |
| Monoisotopic Mass | 472.23352217 |
| Topological Polar Surface Area | 113 |
| Heavy Atom Count | 35 |
| Melting Point | 190-196 |
|---|---|
| Melting Point | 202 °C |
| Solubility | <1 mg/mL |
| Dissociation Constants | pKa1 = 1.9; pKa2 = 8.6 |
Linagliptin; 668270-12-0; Tradjenta; BI-1356; BI 1356; Trazenta; Trajenta; BI-1356-BS; linagliptine; Linagliptina; BS 1356 BS; BI1356; 3X29ZEJ4R2; BI-1356BS; BI 1356 BS; BS-1356-BS
Linagliptin · CAS 668270-12-0 · C25H28N8O2. UNII 3X29ZEJ4R2. Melting Point: 190-196; Melting Point: 202 °C; Solubility: <1 mg/mL.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 利格列汀