乳糖醇（CAS 585-86-4）：分子式 C12H24O11、分子量 344.31；类别 表面活性剂。
| CAS号 | 585-86-4 |
|---|---|
| 分子式 | C12H24O11 |
| 分子量 | 344.31 |
| 熔点 | 146 °C |
| LogP | -5.2 |
| 应用领域 | Uses: CIR ingredient: Lactitol、Lactitol is used as a noncariogenic replacement for sucrose. It is also used as a diluent in solid dosage forms. A direct-compression form is available、as is a direct-compression blend of lactose and lactitol.、Sweetener in food、Use (kg) in Switzerland (2009): >50000、Use (kg、approx.) in Germany (2009): >2500、Consumption (g per capita) in Switzerland (2009): 6.4、Consumption (g per capita、approx.) in Germany (2009): 0.031、Excretion rate: 0.02、Calculated removal (%): 92.1、Use Classification: Food additives、Food Additives -> SWEETENER、TEXTURIZER、THICKENER -> JECFA Functional Classes、Cosmetics -> Humectant、Skin conditioning、Methods of Manufacturing: Lactitol ... is formed from lactose、which is hydrogenated in the presence of Raney-Nickel catalyst. After sedimentation (to settle the catalyst) the solutions is filtered、purified、concentrated and crystallized.、For industrial production、an aqueous lactose solution (30-50 wt%) is hydrogenated at temperatures between 70 and 30 °C and a hydrogen pressure of 30-75 bar. Raney nickel is used as catalyst. After filtration、the material is subjected to ion exchange and concentrated by evaporation. Depending on the crystallization conditions、in particular temperature、lactitol is obtained as anhydrous substance、mono-、or dihydrate. The anhydrous form is formed at higher temperatures.、U.S. Production: Production of lactitol was in 2010 in the range of several thousand、but less than 10、000 tons per year.、General Manufacturing Information: Table of percent relative sweetness and caloric values: [Table#7894]、The sweetness of lactitol is 30-40% of that of sucrose. |
| 类别 | 乳化剂|稳定剂和凝固剂|甜味剂|增稠剂 |
登记用途：Uses: CIR ingredient: Lactitol、Lactitol is used as a noncariogenic replacement for sucrose. It is also used as a diluent in solid dosage forms. A direct-compression form is available、as is a direct-compression blend of lactose and lactitol.、Sweetener in food、Use (kg) in Switzerland (2009): >50000、Use (kg、approx.) in Germany (2009): >2500、Consumption (g per capita) in Switzerland (2009): 6.4、Consumption (g per capita、approx.) in Germany (2009): 0.031、Excretion rate: 0.02、Calculated removal (%): 92.1、Use Classification: Food additives、Food Additives -> SWEETENER、TEXTURIZER、THICKENER -> JECFA Functional Classes、Cosmetics -> Humectant、Skin conditioning、Methods of Manufacturing: Lactitol ... is formed from lactose、which is hydrogenated in the presence of Raney-Nickel catalyst. After sedimentation (to settle the catalyst) the solutions is filtered、purified、concentrated and crystallized.、For industrial production、an aqueous lactose solution (30-50 wt%) is hydrogenated at temperatures between 70 and 30 °C and a hydrogen pressure of 30-75 bar. Raney nickel is used as catalyst. After filtration、the material is subjected to ion exchange and concentrated by evaporation. Depending on the crystallization conditions、in particular temperature、lactitol is obtained as anhydrous substance、mono-、or dihydrate. The anhydrous form is formed at higher temperatures.、U.S. Production: Production of lactitol was in 2010 in the range of several thousand、but less than 10、000 tons per year.、General Manufacturing Information: Table of percent relative sweetness and caloric values: [Table#7894]、The sweetness of lactitol is 30-40% of that of sucrose.。
乳糖醇 是一种表面活性化合物，登记 CAS 号为 585-86-4，分子式 C12H24O11（分子量 344.31），归属于表面活性剂大类化工原料。
登记 CAS 号：585-86-4
其分子式 C12H24O11 由 12 个碳、24 个氢、11 个氧 组成。
别名/同义词：乳糖醇 · lactitol
所属分类：表面活性剂 / 稳定剂和凝固剂 / 甜味剂 / 食品添加剂
乳糖醇 的 CAS 登记号为 585-86-4。
分子式 C12H24O11，分子量 344.31。
别名/同义词：乳糖醇、lactitol。
登记用途：Uses: CIR ingredient: Lactitol、Lactitol is used as a noncariogenic replacement for sucrose. It is also used as a diluent in solid dosage forms. A direct-compression form is available、as is a direct-compression blend of lactose and lactitol.、Sweetener in food、Use (kg) in Switzerland (2009): >50000、Use (kg、approx.) in Germany (2009): >2500、Consumption (g per capita) in Switzerland (2009): 6.4、Consumption (g per capita、approx.) in Germany (2009): 0.031、Excretion rate: 0.02、Calculated removal (%): 92.1、Use Classification: Food additives、Food Additives -> SWEETENER、TEXTURIZER、THICKENER -> JECFA Functional Classes、Cosmetics -> Humectant、Skin conditioning、Methods of Manufacturing: Lactitol ... is formed from lactose、which is hydrogenated in the presence of Raney-Nickel catalyst. After sedimentation (to settle the catalyst) the solutions is filtered、purified、concentrated and crystallized.、For industrial production、an aqueous lactose solution (30-50 wt%) is hydrogenated at temperatures between 70 and 30 °C and a hydrogen pressure of 30-75 bar. Raney nickel is used as catalyst. After filtration、the material is subjected to ion exchange and concentrated by evaporation. Depending on the crystallization conditions、in particular temperature、lactitol is obtained as anhydrous substance、mono-、or dihydrate. The anhydrous form is formed at higher temperatures.、U.S. Production: Production of lactitol was in 2010 in the range of several thousand、but less than 10、000 tons per year.、General Manufacturing Information: Table of percent relative sweetness and caloric values: [Table#7894]、The sweetness of lactitol is 30-40% of that of sucrose.。
所属分类：乳化剂 / 稳定剂和凝固剂 / 甜味剂 / 增稠剂。
乳糖醇（CAS 585-86-4）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 585-86-4 |
|---|---|
| PubChem CID | 157355 |
| 分子式 | C12H24O11 |
| 分子量 | 344.13 g/mol |
| IUPAC 名称 | (2S,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol |
| InChIKey | VQHSOMBJVWLPSR-JVCRWLNRSA-N |
| UNII（FDA） | L2B0WJF7ZY |
| ChEBI 编号 | CHEBI:75323 |
| ATC 编码（WHO） | A06AD12 |
| Molecular Weight | 344.31 |
|---|---|
| XLogP3 | -5.2 |
| Hydrogen Bond Donor Count | 9 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 8 |
| Exact Mass | 344.13186158 |
| Monoisotopic Mass | 344.13186158 |
| Topological Polar Surface Area | 201 |
| Heavy Atom Count | 23 |
| Melting Point | 146 °C |
|---|---|
| Melting Point | 95 - 98 °C |
| Solubility | 667 mg/mL at 25 °C |
lactitol; 585-86-4; 4-O-beta-D-Galactopyranosyl-D-glucitol; Importal; D-lactitol; lactositol; Lactosit; Miruhen; lactitolum; lactobiosit; Lactitol acm 50; LACTITOL ANHYDROUS; Lacty (saccharide); Milchen; Lactit; Finlac dc
| 法规与食品接触 | SWEETENER; TEXTURIZER; THICKENER: Food Additives 乳糖醇是通过乳糖催化氢化生产的 NOT SPECIFIED TRS 696-JECFA 27/23 FAS 18-JECFA 27/82 CIR / INCI: Cosmetic ingredients (Lactitol) -> CIR (Cosmetic Ingredient Review) |
|---|---|
| GHS 通报统计 | 100% (3 / 3) |
| GHS 通报统计 | 100% (3 / 3) |
|---|
乳糖醇 的 CAS 号为 585-86-4，分子式 C12H24O11，分子量 344.13 g/mol。 UNII L2B0WJF7ZY; ChEBI 75323; InChIKey VQHSOMBJVWLPSR-JVCRWLNRSA-N. Melting Point: 146 °C; Melting Point: 95 - 98 °C; Solubility: 667 mg/mL at 25 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: lactitol