伊曲茶碱

伊曲茶碱（CAS 155270-99-8）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

计算分子描述符

在册的理化数值

在册的记载用途

Istradefylline is indicated in adjunct to levodopa and carbidopa in the treatment of Parkinson's disease.Istradefylline is an adenosine receptor antagonist that is used as adjunctive therapy to levodopa/carbidopa in patients with Parkinson disease experiencing difficulty with “off” episodes when motor symptoms breakthrough on treatment. Istradefylline has been associated with a low rate of serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice.

同义词与商品名

Istradefylline; 155270-99-8; KW-6002; nouriast; Nourianz; KW 6002; 8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methylpurine-2,6-dione; istradefilina; DTXSID7057652; 2GZ0LIK7T4; (E)-8-(3,4-Dimethoxystyryl)-1,3-diethyl-7-methyl-3,7-dihydro-1H-purine-2,6-dione; DTXCID8031441; istradefyllinum; 8-((E)-2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-7-methylpurine-2,6-dione; RefChem:57357; 8-(2-(3,4-dimethoxyphenyl)ethenyl)-1,3-diethyl-3,7-dihydro-7-methyl-1H-purine-2,6-dione

GHS 危害分类

Reported hazard statements	H301 (97.4%)

H301 (97.4%): Toxic if swallowed [Danger Acute toxicity, oral]

P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)

公开数据库对它的描述

Istradefylline · CAS 155270-99-8 · C20H24N4O4. UNII 2GZ0LIK7T4. Boiling Point: 601; Melting Point: 189-193; Solubility: 0.5µg/mL.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。