galanthamine hydrobromide

Description

galanthamine hydrobromide · CAS 1953-04-4 · C17H22BrNO3. UNII 5N4SA4KQX9.

Identification

Computed Descriptors

Physical description & handling notes

• 166.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

GHS Hazard Classification

Documented Uses

• For the treatment of mild to moderate dementia of the Alzheimer's type. Has also been investigated in patients with mild cognitive impairment who did not meet the diagnostic criteria for Alzheimer's disease.
• Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here.
• Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.
• Cholinesterase Inhibitors [MoA]; Cholinesterase Inhibitor [EPC]
• Route of Elimination: Galantamine is metabolized by hepatic cytochrome P450 enzymes, glucuronidated, and excreted unchanged in the urine. Half Life: 7 hours

Synonyms

Galanthamine hydrobromide; Galantamine hydrobromide; 1953-04-4; Nivaline; Nivalin; Lycoremine hydrobromide; Jilkon hydrobromide; Tamilin; (-)-Galantamine Hydrobromide; MJ4PTD2VVW; Razadyne ER; RefChem:56717; DTXCID001473878; Benzofuro(4,3,2-efg)(2)benzazocin-6-ol, 1,2,3,4,6,7,7a,11c-octahydro-9-methoxy-2-methyl-, hydrobromide; 217-780-5; DTXSID4052768

Frequently Asked Questions

What are the CAS number and molecular formula of galanthamine hydrobromide?

CAS 1953-04-4; molecular formula C17H22BrNO3; molecular weight — g/mol.

What other names is galanthamine hydrobromide known by?

Galanthamine hydrobromide, Galantamine hydrobromide, 1953-04-4, Nivaline, Nivalin, Lycoremine hydrobromide.

Is galanthamine hydrobromide classified as hazardous?

1.2% of GHS notifications report no hazard classification (1 of 85).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.