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Fluticasone propionate

CAS 80474-14-2C25H31F3O5SMW 500.6

Fluticasone propionate (CAS 80474-14-2) — formula C25H31F3O5S, molecular weight 500.6; category organic chemicals.

Product Overview

CAS Number80474-14-2
Molecular FormulaC25H31F3O5S
Molecular Weight500.6
Melting Point261-273 °C
LogP2.78
ApplicationsUse Classification: Pharmaceuticals
CategoryOrganic Chemicals

Applications

Documented applications: Use Classification: Pharmaceuticals.

Technical Profile

What this product is

Fluticasone propionate is a carbon-based organic compound with CAS registry number 80474-14-2 and molecular formula C25H31F3O5S (molecular weight 500.6), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 80474-14-2

Its molecular formula C25H31F3O5S comprises 25 C, 31 H, 3 F, 5 O, 1 S atoms.

Also known as: Fluticasone propionate · 丙酸氟替卡松

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of Fluticasone propionate?

The CAS registry number of Fluticasone propionate is 80474-14-2.

What is the molecular formula and molecular weight of Fluticasone propionate?

Molecular formula C25H31F3O5S, molecular weight 500.6.

What other names is Fluticasone propionate known by?

It is also registered under: Fluticasone propionate, 丙酸氟替卡松.

What are the documented applications of Fluticasone propionate?

Recorded applications: Use Classification: Pharmaceuticals.

Which category does Fluticasone propionate belong to?

Category: Organic Chemicals.

PubChem Public Data

Independent reference data for Fluticasone propionate (CAS 80474-14-2), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number80474-14-2
PubChem CID444036
Molecular formulaC25H31F3O5S
IUPAC name[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
UNII (FDA)O2GMZ0LF5W

Computed descriptors

Molecular Weight500.6
XLogP34
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass500.18442974
Monoisotopic Mass500.18442974
Topological Polar Surface Area106
Heavy Atom Count34

Physicochemical values on record

Melting Point261-273 °C
LogP2.78

Documented uses on record

    Fluticasone propionate is indicated as an inhaler for the treatment and management of asthma by prophylaxisas well as inflammatory and pruritic dermatoses. Fluticasone propionate nasal spray is indicated for managing allergic and nonallergic rhinitis.Substances that reduce or suppress INFLAMMATION.

    Synonyms and trade names

    FLUTICASONE PROPIONATE; 80474-14-2; Flovent; Cutivate; Flixotide; Flonase; Flovent HFA; Flovent Diskus; Flovent Diskus 50; Flovent Diskus 100; Flovent Diskus 250; Xhance; CCI-18781; ArmonAir RespiClick; CCI 18781; DTXSID8045511

    Regulatory listings held on file

    GHS notification summary10% (2 / 20)

    GHS hazard classification

    GHS notification summary10% (2 / 20)
    Reported hazard statementsH302 (20%), H317 (10%), H334 (10%), H360 (45%), H361 (35%), H373 (65%), H410 (15%), H413 (20%)

    This chemical does not meet GHS hazard criteria for 10% (2 of 20) of reports.

    H302 (20%): Harmful if swallowed [Warning Acute toxicity, oral]

    What the public record says

    Fluticasone propionate · CAS 80474-14-2 · C25H31F3O5S. UNII O2GMZ0LF5W. Melting Point: 261-273 °C; LogP: 2.78.

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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