Felbamate (CAS 25451-15-4) — formula C11H14N2O4, molecular weight 238.24; category organic chemicals.
| CAS Number | 25451-15-4 |
|---|---|
| Molecular Formula | C11H14N2O4 |
| Molecular Weight | 238.24 |
| Melting Point | 151.5 |
| LogP | 0.3 |
| Applications | Uses: MEDICATION, THERAP CAT: Anticonvulsive, Use (kg, approx.) in Germany (2009): >100, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Calculated removal (%): 22, For use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and, or liver failure is deemed acceptable in light of the benefits conferred by its use., Use Classification: Pharmaceuticals, Methods of Manufacturing: 2-Phenyl-1, 3-propanediole is reacted with ethylcarbamate to yield felbamate., Formulations, Preparations: Oral suspension, 600 mg, 5 mL Felbatol ( with polysorbate 80 parabens saccharin sodium and sorbitol), Medpointe, Tablets, 400 mg Felbatol ( scored), Medpoint, 600 mg Felbatol ( scored), Medpointe. |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, THERAP CAT: Anticonvulsive, Use (kg, approx.) in Germany (2009): >100, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Calculated removal (%): 22, For use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and, or liver failure is deemed acceptable in light of the benefits conferred by its use., Use Classification: Pharmaceuticals, Methods of Manufacturing: 2-Phenyl-1, 3-propanediole is reacted with ethylcarbamate to yield felbamate., Formulations, Preparations: Oral suspension, 600 mg, 5 mL Felbatol ( with polysorbate 80 parabens saccharin sodium and sorbitol), Medpointe, Tablets, 400 mg Felbatol ( scored), Medpoint, 600 mg Felbatol ( scored), Medpointe..
Felbamate is a carbon-based organic compound with CAS registry number 25451-15-4 and molecular formula C11H14N2O4 (molecular weight 238.24), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 25451-15-4
Its molecular formula C11H14N2O4 comprises 11 C, 14 H, 2 N, 4 O atoms.
Also known as: Felbamate · 非氨酯
Category: organic chemicals
The CAS registry number of Felbamate is 25451-15-4.
Molecular formula C11H14N2O4, molecular weight 238.24.
It is also registered under: Felbamate, 非氨酯.
Recorded applications: Uses: MEDICATION, THERAP CAT: Anticonvulsive, Use (kg, approx.) in Germany (2009): >100, Consumption (g per capita, approx.) in Germany (2009): 0.00122, Calculated removal (%): 22, For use only in those patients who respond inadequately to alternative treatments and whose epilepsy is so severe that a substantial risk of aplastic anemia and, or liver failure is deemed acceptable in light of the benefits conferred by its use., Use Classification: Pharmaceuticals, Methods of Manufacturing: 2-Phenyl-1, 3-propanediole is reacted with ethylcarbamate to yield felbamate., Formulations, Preparations: Oral suspension, 600 mg, 5 mL Felbatol ( with polysorbate 80 parabens saccharin sodium and sorbitol), Medpointe, Tablets, 400 mg Felbatol ( scored), Medpoint, 600 mg Felbatol ( scored), Medpointe..
Category: Organic Chemicals.
Independent reference data for Felbamate (CAS 25451-15-4), compiled from public chemistry databases.
| CAS Registry Number | 25451-15-4 |
|---|---|
| PubChem CID | 3331 |
| Molecular formula | C11H14N2O4 |
| IUPAC name | (3-carbamoyloxy-2-phenylpropyl) carbamate |
| UNII (FDA) | X72RBB02N8 |
| Molecular Weight | 238.24 |
|---|---|
| XLogP3 | 0.6 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 7 |
| Exact Mass | 238.09535693 |
| Monoisotopic Mass | 238.09535693 |
| Topological Polar Surface Area | 105 |
| Heavy Atom Count | 17 |
| Melting Point | 151.5 |
|---|---|
| Melting Point | 151-153 °C |
| Melting Point | 151.5 °C |
| Solubility | 7.42e-01 g/L |
| LogP | 0.3 |
felbamate; 25451-15-4; Felbatol; 2-Phenyl-1,3-propanediol dicarbamate; Taloxa; Felbamato; Felbamatum; W-554; 1,3-Propanediol, 2-phenyl-, dicarbamate; ADD-03055; DTXSID9023041; W 554; carbamic acid 2-phenyltrimethylene ester; Carbamic acid, 2-phenyltrimethylene ester; 3-(carbamoyloxy)-2-phenylpropyl carbamate; NSC-759866
| GHS notification summary | 2.2% (1 / 45) |
|---|
| GHS notification summary | 2.2% (1 / 45) |
|---|---|
| Reported hazard statements | H317 (95.6%), H334 (95.6%) |
This chemical does not meet GHS hazard criteria for 2.2% (1 of 45) of reports.
H317 (95.6%): May cause an allergic skin reaction [Warning Sensitization, Skin]
Felbamate · CAS 25451-15-4 · C11H14N2O4. UNII X72RBB02N8. Melting Point: 151.5; Melting Point: 151-153 °C; Melting Point: 151.5 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 非氨酯