ethyl ethylcarbamate (CAS 623-78-9) — formula C3H7NO2, molecular weight 89.09; category organic chemicals.
| CAS Number | 623-78-9 |
|---|---|
| Molecular Formula | C3H7NO2 |
| Molecular Weight | 89.09 |
| Melting Point | 118 to 122 °F (NTP, 1992) |
| Boiling Point | 360 to 363 °F at 760 mmHg (NTP, 1992) |
| LogP | -0.2 |
| Applications | Uses: Ethyl carbamate is used as an intermediate in the synthesis of a variety of products (e.g., pharmaceuticals) and as a solubilizer and cosolvent for pesticides and fumigants. Ethyl carbamate has also been used as an anti-neoplastic agent., Used as an antineoplastic agent, veterinary anesthetic, and chemical intermediate, [ChemIDplus] Used as an intermediate, amino resin modifier, solvent, and animal anesthetic, Occurs naturally in fermented wines and foods, [Merck Index], Molten urethan as solvent for various organic materials. Intermediate in organic synthesis. In the preparation and modification of amino resins. As solubilizer and cosolvent for pesticides, fumigants., SOLUBILIZER & CO-SOLVENT FOR COSMETICS., AS CHEMICAL INTERMEDIATE, PRIMARILY FOR REACTION WITH FORMALDEHYDE TO PRODUCE N-HYDROXYMETHYL DERIVATIVES, WHICH ARE USEFUL AS CROSS LINKING AGENTS IN TEXTILE TREATMENTS DESIGNED TO IMPART WASH AND WEAR PROPERTIES TO FABRICS., THERAP CAT: Antineoplastic, For more Uses (Complete) data for ETHYL CARBAMATE (6 total), please visit the HSDB record page., Small quantities of ethyl carbamate are still used in laboratories as an anesthetic for animals. Ethyl carbamate is found in many alcoholic beverages, especially distilled spirits., Use Classification: Food Contaminant -> CONTAMINANT -> JECFA Functional Classes, Methods of Manufacturing: By heating ethanol & urea nitrate at 120-130 °C, by action of ammonia on ethyl carbonate or ethyl chloroformate., Prepared by the reaction of carbamic acid with ethyl alcohol., ... Commercial production is probably the reaction of ethyl chlorocarbonate (made from ethanol and phosgene) with ammonia., Formulations, Preparations: GRADES: Technical, NF., General Manufacturing Information: Carbamic acid, ethyl ester: ACTIVE, URETHANE HAS BEEN REPORTED TO OCCUR AS RESULT OF REACTION OF AMMONIA & DIETHYLPYROCARBONATE ADDED AT LEVELS OF 10 UG, L IN CERTAIN BEVERAGES AT PH BELOW 4.0 ... ALSO ... IN DIETHYLPYROCARBONATE TREATED WINES AT LEVELS UP TO 50 UG, L, IT WAS CONSIDERED POSSIBLE THAT SOME OF THIS WAS OF NATURAL ORIGIN ... ., ... Urethane can occur as a contaminant in two anticonvulsant drugs (trimethadione and paramethadione), with an allowable limit of 1 ppm, these anticonvulsant drugs may be used only to treat epilepsy. ..., Ethyl carbamate was in use in Japan from 1950 to 1975 as a cosolvent for dissolving water insoluble analgesic drugs, but this practice was stopped after 1975. |
| Category | Organic Chemicals |
Documented applications: Uses: Ethyl carbamate is used as an intermediate in the synthesis of a variety of products (e.g., pharmaceuticals) and as a solubilizer and cosolvent for pesticides and fumigants. Ethyl carbamate has also been used as an anti-neoplastic agent., Used as an antineoplastic agent, veterinary anesthetic, and chemical intermediate, [ChemIDplus] Used as an intermediate, amino resin modifier, solvent, and animal anesthetic, Occurs naturally in fermented wines and foods, [Merck Index], Molten urethan as solvent for various organic materials. Intermediate in organic synthesis. In the preparation and modification of amino resins. As solubilizer and cosolvent for pesticides, fumigants., SOLUBILIZER & CO-SOLVENT FOR COSMETICS., AS CHEMICAL INTERMEDIATE, PRIMARILY FOR REACTION WITH FORMALDEHYDE TO PRODUCE N-HYDROXYMETHYL DERIVATIVES, WHICH ARE USEFUL AS CROSS LINKING AGENTS IN TEXTILE TREATMENTS DESIGNED TO IMPART WASH AND WEAR PROPERTIES TO FABRICS., THERAP CAT: Antineoplastic, For more Uses (Complete) data for ETHYL CARBAMATE (6 total), please visit the HSDB record page., Small quantities of ethyl carbamate are still used in laboratories as an anesthetic for animals. Ethyl carbamate is found in many alcoholic beverages, especially distilled spirits., Use Classification: Food Contaminant -> CONTAMINANT -> JECFA Functional Classes, Methods of Manufacturing: By heating ethanol & urea nitrate at 120-130 °C, by action of ammonia on ethyl carbonate or ethyl chloroformate., Prepared by the reaction of carbamic acid with ethyl alcohol., ... Commercial production is probably the reaction of ethyl chlorocarbonate (made from ethanol and phosgene) with ammonia., Formulations, Preparations: GRADES: Technical, NF., General Manufacturing Information: Carbamic acid, ethyl ester: ACTIVE, URETHANE HAS BEEN REPORTED TO OCCUR AS RESULT OF REACTION OF AMMONIA & DIETHYLPYROCARBONATE ADDED AT LEVELS OF 10 UG, L IN CERTAIN BEVERAGES AT PH BELOW 4.0 ... ALSO ... IN DIETHYLPYROCARBONATE TREATED WINES AT LEVELS UP TO 50 UG, L, IT WAS CONSIDERED POSSIBLE THAT SOME OF THIS WAS OF NATURAL ORIGIN ... ., ... Urethane can occur as a contaminant in two anticonvulsant drugs (trimethadione and paramethadione), with an allowable limit of 1 ppm, these anticonvulsant drugs may be used only to treat epilepsy. ..., Ethyl carbamate was in use in Japan from 1950 to 1975 as a cosolvent for dissolving water insoluble analgesic drugs, but this practice was stopped after 1975..
ethyl ethylcarbamate is a carbon-based organic compound with CAS registry number 623-78-9 and molecular formula C3H7NO2 (molecular weight 89.09), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 623-78-9
Its molecular formula C3H7NO2 comprises 3 C, 7 H, 1 N, 2 O atoms.
Also known as: ethyl ethylcarbamate · 乙基氨基甲酸乙酯
Category: organic chemicals
The CAS registry number of ethyl ethylcarbamate is 623-78-9.
Molecular formula C3H7NO2, molecular weight 89.09.
It is also registered under: ethyl ethylcarbamate, 乙基氨基甲酸乙酯.
Recorded applications: Uses: Ethyl carbamate is used as an intermediate in the synthesis of a variety of products (e.g., pharmaceuticals) and as a solubilizer and cosolvent for pesticides and fumigants. Ethyl carbamate has also been used as an anti-neoplastic agent., Used as an antineoplastic agent, veterinary anesthetic, and chemical intermediate, [ChemIDplus] Used as an intermediate, amino resin modifier, solvent, and animal anesthetic, Occurs naturally in fermented wines and foods, [Merck Index], Molten urethan as solvent for various organic materials. Intermediate in organic synthesis. In the preparation and modification of amino resins. As solubilizer and cosolvent for pesticides, fumigants., SOLUBILIZER & CO-SOLVENT FOR COSMETICS., AS CHEMICAL INTERMEDIATE, PRIMARILY FOR REACTION WITH FORMALDEHYDE TO PRODUCE N-HYDROXYMETHYL DERIVATIVES, WHICH ARE USEFUL AS CROSS LINKING AGENTS IN TEXTILE TREATMENTS DESIGNED TO IMPART WASH AND WEAR PROPERTIES TO FABRICS., THERAP CAT: Antineoplastic, For more Uses (Complete) data for ETHYL CARBAMATE (6 total), please visit the HSDB record page., Small quantities of ethyl carbamate are still used in laboratories as an anesthetic for animals. Ethyl carbamate is found in many alcoholic beverages, especially distilled spirits., Use Classification: Food Contaminant -> CONTAMINANT -> JECFA Functional Classes, Methods of Manufacturing: By heating ethanol & urea nitrate at 120-130 °C, by action of ammonia on ethyl carbonate or ethyl chloroformate., Prepared by the reaction of carbamic acid with ethyl alcohol., ... Commercial production is probably the reaction of ethyl chlorocarbonate (made from ethanol and phosgene) with ammonia., Formulations, Preparations: GRADES: Technical, NF., General Manufacturing Information: Carbamic acid, ethyl ester: ACTIVE, URETHANE HAS BEEN REPORTED TO OCCUR AS RESULT OF REACTION OF AMMONIA & DIETHYLPYROCARBONATE ADDED AT LEVELS OF 10 UG, L IN CERTAIN BEVERAGES AT PH BELOW 4.0 ... ALSO ... IN DIETHYLPYROCARBONATE TREATED WINES AT LEVELS UP TO 50 UG, L, IT WAS CONSIDERED POSSIBLE THAT SOME OF THIS WAS OF NATURAL ORIGIN ... ., ... Urethane can occur as a contaminant in two anticonvulsant drugs (trimethadione and paramethadione), with an allowable limit of 1 ppm, these anticonvulsant drugs may be used only to treat epilepsy. ..., Ethyl carbamate was in use in Japan from 1950 to 1975 as a cosolvent for dissolving water insoluble analgesic drugs, but this practice was stopped after 1975..
Category: Organic Chemicals.
Independent reference data for ethyl ethylcarbamate (CAS 623-78-9), compiled from public chemistry databases.
| CAS Registry Number | 623-78-9 |
|---|---|
| PubChem CID | 5641 |
| Molecular formula | C3H7NO2 |
| IUPAC name | ethyl carbamate |
| UNII (FDA) | 3IN71E75Z5 |
| Molecular Weight | 89.09 |
|---|---|
| XLogP3 | -0.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 89.047678466 |
| Monoisotopic Mass | 89.047678466 |
| Topological Polar Surface Area | 52.3 |
| Heavy Atom Count | 6 |
| Boiling Point | 360 to 363 °F at 760 mmHg (NTP, 1992) |
|---|---|
| Boiling Point | 185 |
| Boiling Point | 185 °C |
| Boiling Point | 185.00 °C. @ 760.00 mm Hg |
| Melting Point | 118 to 122 °F (NTP, 1992) |
| Melting Point | 49 |
| Melting Point | 49 °C |
| Melting Point | 48.5 - 50 °C |
| Flash Point | 198 °F (NTP, 1992) |
| Flash Point | 92 °C c.c. |
urethane; ETHYL CARBAMATE; 51-79-6; Carbamic acid, ethyl ester; Leucethane; Pracarbamine; Carbamic acid ethyl ester; Ethyl urethane; Ethylcarbamate; Ethylurethane; O-Ethylurethane; Pracarbamin; Ethyl urethan; Leucothane; U-Compound; Aethylcarbamat
| Regulatory & Food Contact | CONTAMINANT: Food Contaminant TRS 930-JECFA 64/31 FAS 55-JECFA 64/205 |
|---|
| Reported hazard statements | H350, H302 (27.1%), H312, H336, H341, H361, H373, H340 |
|---|
H350: May cause cancer [Danger Carcinogenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
ethyl ethylcarbamate · CAS 623-78-9 · C3H7NO2. UNII 3IN71E75Z5. Boiling Point: 360 to 363 °F at 760 mmHg (NTP, 1992); Boiling Point: 185; Boiling Point: 185 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 乙基氨基甲酸乙酯