乙磺酰亚胺（CAS 77-67-8）：分子式 C7H11NO2、分子量 141.17。
| CAS号 | 77-67-8 |
|---|---|
| 分子式 | C7H11NO2 |
| 分子量 | 141.17 |
| 熔点 | 64.5 |
| LogP | 0.38 |
| 应用领域 | Uses: Antiepileptic、THERAP CAT: Anticonvulsant、MEDICATION、For the treatment of petit mal epilepsy.、Use Classification: Pharmaceuticals、Methods of Manufacturing: The condensation of butanone with cyano ethyl acetate and subsequent reaction with NaCN and H2SO4 gives 2-ethyl-2-methyl-succinic acid、which is ring-closed via the diammonium salt to yield ethosuximide.、Methyl ethyl ketone + ethyl cyanoacetate + hydrogen cyanide + ammonia (Cope reaction、addition、nitrile hydrolysis、decarboxylation、ester hydrolysis、amide formation)、Formulations、Preparations: ASAMID、ATYSMAL、CAPITUS、EMESIDE、For more Formulations、Preparations (Complete) data for ETHOSUXIMIDE (31 total)、please visit the HSDB record page.、U.S. Production: (1972) LESS THAN 10+7 GRAMS (CONSUMPTION EST)、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) No Data、General Manufacturing Information: US PATENT 2、993、835. |
登记用途：Uses: Antiepileptic、THERAP CAT: Anticonvulsant、MEDICATION、For the treatment of petit mal epilepsy.、Use Classification: Pharmaceuticals、Methods of Manufacturing: The condensation of butanone with cyano ethyl acetate and subsequent reaction with NaCN and H2SO4 gives 2-ethyl-2-methyl-succinic acid、which is ring-closed via the diammonium salt to yield ethosuximide.、Methyl ethyl ketone + ethyl cyanoacetate + hydrogen cyanide + ammonia (Cope reaction、addition、nitrile hydrolysis、decarboxylation、ester hydrolysis、amide formation)、Formulations、Preparations: ASAMID、ATYSMAL、CAPITUS、EMESIDE、For more Formulations、Preparations (Complete) data for ETHOSUXIMIDE (31 total)、please visit the HSDB record page.、U.S. Production: (1972) LESS THAN 10+7 GRAMS (CONSUMPTION EST)、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) No Data、General Manufacturing Information: US PATENT 2、993、835.。
乙磺酰亚胺 是一种化工化合物，登记 CAS 号为 77-67-8，分子式 C7H11NO2（分子量 141.17）。
登记 CAS 号：77-67-8
其分子式 C7H11NO2 由 7 个碳、11 个氢、1 个氮、2 个氧 组成。
别名/同义词：乙磺酰亚胺 · ethosuximide · Petinimid
乙磺酰亚胺 的 CAS 登记号为 77-67-8。
分子式 C7H11NO2，分子量 141.17。
别名/同义词：乙磺酰亚胺、ethosuximide、Petinimid。
登记用途：Uses: Antiepileptic、THERAP CAT: Anticonvulsant、MEDICATION、For the treatment of petit mal epilepsy.、Use Classification: Pharmaceuticals、Methods of Manufacturing: The condensation of butanone with cyano ethyl acetate and subsequent reaction with NaCN and H2SO4 gives 2-ethyl-2-methyl-succinic acid、which is ring-closed via the diammonium salt to yield ethosuximide.、Methyl ethyl ketone + ethyl cyanoacetate + hydrogen cyanide + ammonia (Cope reaction、addition、nitrile hydrolysis、decarboxylation、ester hydrolysis、amide formation)、Formulations、Preparations: ASAMID、ATYSMAL、CAPITUS、EMESIDE、For more Formulations、Preparations (Complete) data for ETHOSUXIMIDE (31 total)、please visit the HSDB record page.、U.S. Production: (1972) LESS THAN 10+7 GRAMS (CONSUMPTION EST)、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) No Data、General Manufacturing Information: US PATENT 2、993、835.。
乙磺酰亚胺（CAS 77-67-8）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 77-67-8 |
|---|---|
| PubChem CID | 3291 |
| Molecular formula | C7H11NO2 |
| IUPAC name | 3-ethyl-3-methylpyrrolidine-2,5-dione |
| UNII (FDA) | 5SEH9X1D1D |
| Molecular Weight | 141.17 |
|---|---|
| XLogP3 | 0.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 141.078978594 |
| Monoisotopic Mass | 141.078978594 |
| Topological Polar Surface Area | 46.2 |
| Heavy Atom Count | 10 |
| Melting Point | 64.5 |
|---|---|
| Melting Point | 64 - 65 °C |
| Melting Point | 64.5 °C |
| Solubility | 39.2 |
| Solubility | 1.01e+02 g/L |
| LogP | 0.38 |
| LogP | log Kow = 0.38 |
| LogP | 0.1 |
| LogP | 0.23 |
ethosuximide; 77-67-8; Zarontin; Etosuximida; 3-Ethyl-3-methylpyrrolidine-2,5-dione; 2-Ethyl-2-methylsuccinimide; Ethosuxide; Pyknolepsinum; Emeside; Suxilep; Ethosuccimide; Ethosuccinimide; Atysmal; Suxinutin; Etosuximid; Petinimid
| Reported hazard statements | H302 (95.7%) |
|---|
H302 (95.7%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Petinimid · CAS 77-67-8 · C7H11NO2. UNII 5SEH9X1D1D. Melting Point: 64.5; Melting Point: 64 - 65 °C; Melting Point: 64.5 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: ethosuximide