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ERYTHORBIC ACID

CAS 89-65-6C6H8O6MW 176.12

ERYTHORBIC ACID (CAS 89-65-6) — formula C6H8O6, molecular weight 176.12.

Product Overview

CAS Number89-65-6
Molecular FormulaC6H8O6
Molecular Weight176.12
Melting PointDecomposes at 174 °C
LogP-1.6
ApplicationsUses: CIR ingredient: Erythorbic Acid, Used as an antioxidant (brewing industry), reducing agent (photography), and flavor, [HSDB] Used as antimicrobial agent for food, [Merck Index] An isomer of ascorbic acid used as a food antioxidant, [REPROTOX], Photographic Processing [Category: Other], Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant., Reported uses, Table: Reported uses (ppm) for Erythorbic acid [Table#1683], Antioxidant especially in brewing industry, reducing agent in photography, Synthetic flavor, For more Uses (Complete) data for Erythorbic acid (8 total), please visit the HSDB record page., Use Classification: Food additives, Food Additives -> ANTIOXIDANT -> JECFA Functional Classes, Cosmetics -> Antioxidant, Industry Uses: Reducing agent, Preservative, Not Known or Reasonably Ascertainable, Consumer Uses: Preservative, Household Products: Information on 206 consumer products that contain Isoascorbic acid in the following categories is provided:, • Inside the Home, • Personal Care, Methods of Manufacturing: Erythorbic acid is synthesized by the reaction between methyl 2-keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose and produced from Penicillium spp., Erythorbic acid can also be prepared by reacting 2-keto-D-gluconate with sodium methoxide, synthesized from sucrose, or naturally produced by Penicililum species. Sodium erythorbate is prepared from D-glucose by a combination of biosynthesis and chemical synthesis via the intermediate 2-keto-D-gluconic acid., Erythorbic acid is produced by the fermentation of D-glucose to 2-keto-D-gluconic acid by Pseudomonas fluorescens bacteria. The fermentation product is esterified and heated in basic solution to yield sodium erythorbate. Upon acidification of the salt in a water-methanol solution, erythorbic acid is formed., Formulations, Preparations: Mercate "20", Neo-cebitate., Sodium Erythorbate, Grade: FCC., U.S. Production: 2023: 400, 000 - <550, 000 lb, 2022: 550, 000 - <1, 000, 2021: 400, 2020: 400, (1972) Probably > 4.54 x 10+5 g, (1975) Probably > 9.1 x 10+5 g, D-erythro-Hex-2-enonic acid, .gamma.-lactone is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#1682], Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: D-erythro-Hex-2-enonic acid, .gamma.-lactone. Aggregated National Production Volume: 500, 000 to < 1 million lbs., General Manufacturing Information: Not Known or Reasonably Ascertainable, All Other Chemical Product and Preparation Manufacturing, Plastics Material and Resin Manufacturing, Paint and Coating Manufacturing, Food, beverage, and tobacco product manufacturing, .gamma.-lactone: ACTIVE, Has one-twentieth of the vitamin C activity of L-ascorbic acid, ...Used to prevent nitrosoamine formation from nitrites in cured meats such as bacon., Mid regulation, limitations: to accelerate color fixing in cured pork and beef cuts and cured comminuted meat food products, 3, 4 ounce to 100 lb meat or meat by-product.

Applications

Documented applications: Uses: CIR ingredient: Erythorbic Acid, Used as an antioxidant (brewing industry), reducing agent (photography), and flavor, [HSDB] Used as antimicrobial agent for food, [Merck Index] An isomer of ascorbic acid used as a food antioxidant, [REPROTOX], Photographic Processing [Category: Other], Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant., Reported uses, Table: Reported uses (ppm) for Erythorbic acid [Table#1683], Antioxidant especially in brewing industry, reducing agent in photography, Synthetic flavor, For more Uses (Complete) data for Erythorbic acid (8 total), please visit the HSDB record page., Use Classification: Food additives, Food Additives -> ANTIOXIDANT -> JECFA Functional Classes, Cosmetics -> Antioxidant, Industry Uses: Reducing agent, Preservative, Not Known or Reasonably Ascertainable, Consumer Uses: Preservative, Household Products: Information on 206 consumer products that contain Isoascorbic acid in the following categories is provided:, • Inside the Home, • Personal Care, Methods of Manufacturing: Erythorbic acid is synthesized by the reaction between methyl 2-keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose and produced from Penicillium spp., Erythorbic acid can also be prepared by reacting 2-keto-D-gluconate with sodium methoxide, synthesized from sucrose, or naturally produced by Penicililum species. Sodium erythorbate is prepared from D-glucose by a combination of biosynthesis and chemical synthesis via the intermediate 2-keto-D-gluconic acid., Erythorbic acid is produced by the fermentation of D-glucose to 2-keto-D-gluconic acid by Pseudomonas fluorescens bacteria. The fermentation product is esterified and heated in basic solution to yield sodium erythorbate. Upon acidification of the salt in a water-methanol solution, erythorbic acid is formed., Formulations, Preparations: Mercate "20", Neo-cebitate., Sodium Erythorbate, Grade: FCC., U.S. Production: 2023: 400, 000 - <550, 000 lb, 2022: 550, 000 - <1, 000, 2021: 400, 2020: 400, (1972) Probably > 4.54 x 10+5 g, (1975) Probably > 9.1 x 10+5 g, D-erythro-Hex-2-enonic acid, .gamma.-lactone is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#1682], Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: D-erythro-Hex-2-enonic acid, .gamma.-lactone. Aggregated National Production Volume: 500, 000 to < 1 million lbs., General Manufacturing Information: Not Known or Reasonably Ascertainable, All Other Chemical Product and Preparation Manufacturing, Plastics Material and Resin Manufacturing, Paint and Coating Manufacturing, Food, beverage, and tobacco product manufacturing, .gamma.-lactone: ACTIVE, Has one-twentieth of the vitamin C activity of L-ascorbic acid, ...Used to prevent nitrosoamine formation from nitrites in cured meats such as bacon., Mid regulation, limitations: to accelerate color fixing in cured pork and beef cuts and cured comminuted meat food products, 3, 4 ounce to 100 lb meat or meat by-product..

Technical Profile

What this product is

ERYTHORBIC ACID is a chemical compound with CAS registry number 89-65-6 and molecular formula C6H8O6 (molecular weight 176.12).

Identification

CAS number: 89-65-6

Its molecular formula C6H8O6 comprises 6 C, 8 H, 6 O atoms.

Also known as: ERYTHORBIC ACID · D-Isoascorbic acid

Frequently Asked Questions

What is the CAS number of ERYTHORBIC ACID?

The CAS registry number of ERYTHORBIC ACID is 89-65-6.

What is the molecular formula and molecular weight of ERYTHORBIC ACID?

Molecular formula C6H8O6, molecular weight 176.12.

What other names is ERYTHORBIC ACID known by?

It is also registered under: ERYTHORBIC ACID, D-Isoascorbic acid.

What are the documented applications of ERYTHORBIC ACID?

Recorded applications: Uses: CIR ingredient: Erythorbic Acid, Used as an antioxidant (brewing industry), reducing agent (photography), and flavor, [HSDB] Used as antimicrobial agent for food, [Merck Index] An isomer of ascorbic acid used as a food antioxidant, [REPROTOX], Photographic Processing [Category: Other], Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant., Reported uses, Table: Reported uses (ppm) for Erythorbic acid [Table#1683], Antioxidant especially in brewing industry, reducing agent in photography, Synthetic flavor, For more Uses (Complete) data for Erythorbic acid (8 total), please visit the HSDB record page., Use Classification: Food additives, Food Additives -> ANTIOXIDANT -> JECFA Functional Classes, Cosmetics -> Antioxidant, Industry Uses: Reducing agent, Preservative, Not Known or Reasonably Ascertainable, Consumer Uses: Preservative, Household Products: Information on 206 consumer products that contain Isoascorbic acid in the following categories is provided:, • Inside the Home, • Personal Care, Methods of Manufacturing: Erythorbic acid is synthesized by the reaction between methyl 2-keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose and produced from Penicillium spp., Erythorbic acid can also be prepared by reacting 2-keto-D-gluconate with sodium methoxide, synthesized from sucrose, or naturally produced by Penicililum species. Sodium erythorbate is prepared from D-glucose by a combination of biosynthesis and chemical synthesis via the intermediate 2-keto-D-gluconic acid., Erythorbic acid is produced by the fermentation of D-glucose to 2-keto-D-gluconic acid by Pseudomonas fluorescens bacteria. The fermentation product is esterified and heated in basic solution to yield sodium erythorbate. Upon acidification of the salt in a water-methanol solution, erythorbic acid is formed., Formulations, Preparations: Mercate "20", Neo-cebitate., Sodium Erythorbate, Grade: FCC., U.S. Production: 2023: 400, 000 - <550, 000 lb, 2022: 550, 000 - <1, 000, 2021: 400, 2020: 400, (1972) Probably > 4.54 x 10+5 g, (1975) Probably > 9.1 x 10+5 g, D-erythro-Hex-2-enonic acid, .gamma.-lactone is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#1682], Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: D-erythro-Hex-2-enonic acid, .gamma.-lactone. Aggregated National Production Volume: 500, 000 to < 1 million lbs., General Manufacturing Information: Not Known or Reasonably Ascertainable, All Other Chemical Product and Preparation Manufacturing, Plastics Material and Resin Manufacturing, Paint and Coating Manufacturing, Food, beverage, and tobacco product manufacturing, .gamma.-lactone: ACTIVE, Has one-twentieth of the vitamin C activity of L-ascorbic acid, ...Used to prevent nitrosoamine formation from nitrites in cured meats such as bacon., Mid regulation, limitations: to accelerate color fixing in cured pork and beef cuts and cured comminuted meat food products, 3, 4 ounce to 100 lb meat or meat by-product..

PubChem Public Data

Independent reference data for ERYTHORBIC ACID (CAS 89-65-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number89-65-6
PubChem CID54675810
Molecular formulaC6H8O6
IUPAC name(2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
UNII (FDA)311332OII1
FEMA number2410

Computed descriptors

Molecular Weight176.12
XLogP3-1.6
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass176.03208797
Monoisotopic Mass176.03208797
Topological Polar Surface Area107
Heavy Atom Count12

Physicochemical values on record

Melting PointDecomposes at 174 °C
DecompositionDecomposition at 184 °C.

Documented uses on record

    CIR ingredient: Erythorbic AcidUsed as an antioxidant (brewing industry), reducing agent (photography), and flavor; [HSDB] Used as antimicrobial agent for food; [Merck Index] An isomer of ascorbic acid used as a food antioxidant; [REPROTOX]

    Synonyms and trade names

    Erythorbic acid; 89-65-6; Isoascorbic acid; D-Isoascorbic acid; D-Araboascorbic acid; D-Erythorbic acid; Araboascorbic acid; Isovitamin C; Glucosaccharonic acid; Erycorbin; Neo-cebicure; Saccharosonic acid; Mercate 5; FEMA Number: 2410; D-erythro-3-Ketohexonic acid lactone; FEMA No. 2410

    Regulatory listings held on file

    Regulatory & Food ContactFDA Substance added to food: ANTIMICROBIAL AGENT, ANTIOXIDANT, COLOR OR COLORING ADJUNCT, CURING OR PICKLING
    FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
    ANTIOXIDANT: Food Additives
    ANTIMICROBIAL AGENT, ANTIOXIDANT, COLOR OR COLORING ADJUNCT, CURING OR PICKLING AGENT, FLAVOR ENHANCER, FLAVOR
    NOT SPECIFIED
    TRS 806-JECFA 37/9
    GHS notification summary51.2% (310 / 605)

    GHS hazard classification

    GHS notification summary51.2% (310 / 605)
    Reported hazard statementsH315 (46%), H319 (46.3%), H335 (45.6%)

    This chemical does not meet GHS hazard criteria for 51.2% (310 of 605) of all reports.

    H315 (46%): Causes skin irritation [Warning Skin corrosion/irritation]

    What the public record says

    ERYTHORBIC ACID · CAS 89-65-6 · C6H8O6. UNII 311332OII1. Melting Point: Decomposes at 174 °C; Decomposition: Decomposition at 184 °C..

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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