甲磺酸艾日布林

Description

Eribulin Mesilate · CAS 441045-17-6 · C41H63NO14S. UNII AV9U0660CW.

Identification

CAS Registry Number	441045-17-6
PubChem CID	17755248
Molecular formula	C41H63NO14S
IUPAC name	(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.13,32.13,33.16,9.112,16.018,22.029,36.031,35]hentetracontan-24-one;methanesulfonic acid
UNII (FDA)	AV9U0660CW

Computed Descriptors

Molecular Weight	826.0
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	15
Rotatable Bond Count	4
Exact Mass	825.39692686
Monoisotopic Mass	825.39692686
Topological Polar Surface Area	209
Heavy Atom Count	57
Formal Charge	0
Complexity	1470

GHS Hazard Classification

Reported hazard statements	H341 (100%), H361 (100%), H400 (50%), H410 (100%), H411 (50%)

Documented Uses

• Breast Feeding; Lactation; Milk, Human; Antineoplastic Agents; Antimitotic Agents
• Eribulin mesylate is approved to treat:
• • Breast cancer that has metastasized (spread to other parts of the body). It is used in patients who have already been treated with at least 2 types of chemotherapy for metastatic cancer, including an anthracycline and a taxane.
• • Liposarcoma (a type of soft tissue sarcoma) that cannot be removed by surgery or has metastasized. It is used in patients who have already been treated with anthracycline chemotherapy.
• Eribulin mesylate is also being studied in the treatment of other types of cancer.
• Microtubule Inhibitor [EPC]; Microtubule Inhibition [PE]

Synonyms

Eribulin mesylate; 441045-17-6; Halaven; Eribulin mesilate; Eribulin (as mesylate); E7389; Eribulin monomethanesulfonate; B1939 mesylate; AV9U0660CW; E-7389; CHEBI:70710; NSC707389; Halichondrin B Analog; RefChem:56931; Eribulin (mesylate); Eribulin mesylate [USAN]

Frequently Asked Questions

What are the CAS number and molecular formula of Eribulin Mesilate?

CAS 441045-17-6; molecular formula C41H63NO14S; molecular weight — g/mol.

What other names is Eribulin Mesilate known by?

Eribulin mesylate, 441045-17-6, Halaven, Eribulin mesilate, Eribulin (as mesylate), E7389.

Is Eribulin Mesilate classified as hazardous?

Hazard statements reported: H341, H361, H400, H410, H411.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.