Enasidenib

Name: Enasidenib
Brand: 济南圣和化工有限公司

CAS 1446502-11-9C19H17F6N7OMW 473.4

济南圣和化工有限公司现供应Organic Chemicals——Enasidenib（CAS 1446502-11-9），分子式 C19H17F6N7O，分子量 473.4。本页理化参数仅供参考，实际常规纯度按批次COA提供(不公开发布)，以批次 COA 及订单确认为准，支持批量采购与长期供货协议。

产品概览

CAS号	1446502-11-9
分子式	C19H17F6N7O
分子量	473.4
LogP	3.5
纯度	按批次COA提供(不公开发布)
包装	按订单/批次确认(不公开发布)
应用领域	Organic Chemicals
类别	Organic Chemicals

应用领域

Organic Chemicals

该产品的下游应用集中在Organic Chemicals。不同客户工艺差异较大，我们支持按需提供样品与小批量试用。

包装与储存

包装规格按订单/批次确认(不公开发布)

纯度规格按批次COA提供(不公开发布)

储存条件密封、阴凉干燥处保存

运输常规化工运输

样品可协商提供

交期现货/按订单安排

供应说明：Enasidenib 常规包装为按订单/批次确认(不公开发布)，储存时应密封置于阴凉干燥处，避免与氧化剂混放。济南圣和化工有限公司支持国内物流发货，大货交期与运费以订单确认为准。

质量与文件

每批产品随货提供 COA（分析证书）；可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择济南圣和化工有限公司的理由：产品信息透明（含 CAS、分子式、理化参数）、报价响应快（一个工作日内）、单证齐全（COA/MSS/质检资料按需提供）、支持批量与长期协议供货。如需 Enasidenib 以外的配套原料，也欢迎一并列出需求清单。

常见问题

Enasidenib 的 CAS 号是多少？

Enasidenib 的 CAS 号为 1446502-11-9。

该产品的纯度和包装规格是什么？

常规纯度规格为按批次COA提供(不公开发布)，包装为按订单/批次确认(不公开发布)，随货提供 COA。

Enasidenib 有什么用途？

主要应用于Organic Chemicals。

如何购买或获取报价？

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系，注明产品名称、CAS 号与需求数量，一个工作日内回复报价。供应商：济南圣和化工有限公司。

PubChem 公开数据

Description

Enasidenib · CAS 1446502-11-9 · C19H17F6N7O. UNII 3T1SS4E7AG.

Identification

CAS Registry Number	1446502-11-9
PubChem CID	89683805
Molecular formula	C19H17F6N7O
IUPAC name	2-methyl-1-[[4-[6-(trifluoromethyl)-2-pyridinyl]-6-[[2-(trifluoromethyl)-4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol
UNII (FDA)	3T1SS4E7AG

Computed Descriptors

Molecular Weight	473.4
XLogP3	3.5
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	6
Exact Mass	473.13987716
Monoisotopic Mass	473.13987716
Topological Polar Surface Area	109
Heavy Atom Count	33
Formal Charge	0

GHS Hazard Classification

Reported hazard statements	H360 (50%), H373 (100%), H413 (50%)

H360 (50%): May damage fertility or the unborn child [Danger Reproductive toxicity]

H361f (50%): Suspected of damaging fertility [Warning Reproductive toxicity]

Documented Uses

Enasidenib is indicated for the treatment of adult patients with relapsed or refractory acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation as detected by an FDA-approved test.
Enasidenib is an orally available small molecule inhibitor of mutant isocitrate dehydrogenase-2 that is used in the therapy of selected cases of acute myelogenous leukemia (AML). Enasidenib is associated with a moderate rate of serum aminotransferase elevations during therapy and is suspected to cause rare instances of clinically apparent acute liver injury.
Breast Feeding; Lactation; Antineoplastic Agents; Enzyme Inhibitors; Isocitrate Dehydrogenase Inhibitors
Exercise caution with grapefruit products. Grapefruit inhibits CYP3A4 metabolism, which may increase the serum concentration of enasidenib; however, CYP3A4 is one of many enzymes involved in enasidenib metabolism.
Exercise caution with St. John's Wort. This herb induces CYP3A4 metabolism, which may reduce the serum concentration of enasidenib; however, CYP3A4 is one of many enzymes involved in enasidenib metabolism.
Take at the same time every day.

Synonyms

Enasidenib; 1446502-11-9; CC-90007 Free Base; enasidenibum; 3T1SS4E7AG; CHEBI:145374; DTXSID801027942; RefChem:58279; L01XX59; DTXCID401513509; 107-597-8; AG-221; IDHIFA; AG-221 (Enasidenib); Enasidenib [INN]; AG 221

Frequently Asked Questions

What are the CAS number and molecular formula of Enasidenib?

CAS 1446502-11-9; molecular formula C19H17F6N7O; molecular weight — g/mol.

What other names is Enasidenib known by?

Enasidenib, 1446502-11-9, CC-90007 Free Base, enasidenibum, 3T1SS4E7AG, CHEBI:145374.

Is Enasidenib classified as hazardous?

Hazard statements reported: H360, H373, H413.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.