dopamine

Description

dopamine · CAS 51-61-6 · C8H11NO2. UNII VTD58H1Z2X. Boiling Point: 227; Melting Point: 128; Melting Point: 128 °C.

Identification

CAS Registry Number	51-61-6
PubChem CID	681
Molecular formula	C8H11NO2
IUPAC name	4-(2-aminoethyl)benzene-1,2-diol
UNII (FDA)	VTD58H1Z2X

Computed Descriptors

Molecular Weight	153.18
XLogP3	-1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	153.078978594
Monoisotopic Mass	153.078978594
Topological Polar Surface Area	66.5
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Boiling Point	227
Melting Point	128
Melting Point	128 °C
Solubility	600
Solubility	535 mg/mL
LogP	-0.98
LogP	log Kow = -0.98
LogP	-0.97
Ionization Efficiency	2.72
Ionization Efficiency	2.7

Physical description & handling notes

• Solid
• Stout prisms
• Freely sol in water; sol in methanol, in hot 95% ethanol, in aq soln of alkali hydroxides; practically insol in petroleum ether, ether, benzene, chloroform, toluene /Hydrochloride/
• Freely soluble in water, methanol, and hot 95% ethanol but is practically insoluble in ether, petroleum ether, chloroform, benzene, and toluene.
• Highly sensitive to oxygen; discolors quickly
• Extremely unstable in alkaline media; sensitive to light; stable for 1 yr at 55 °C /Hydrochloride/

GHS Hazard Classification

Reported hazard statements	H302 (100%), H361 (100%), H400 (100%), H410 (100%)

Documented Uses

• ... used in the treatment of severe congestive /heart/ failure ... also may improve physiological parameters in the treatment of cardiogenic and septic shock
• For the correction of hemodynamic imbalances present in shock ... due to mycocardial infarction, trauma, endotoxin septicemia, open-heart surgery, and chronic cardiac decompensation as in congestive failure
• Therapeutic Category: Cardiotonic; antihypotensive
• Use (kg; approx.) in Germany (2009): >25
• Consumption (g per capita; approx.) in Germany (2009): 0.000305
• For the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarction, trauma, endotoxic septicemia, open-heart surgery, renal failure, and chronic cardiac decompensation as in congestive failure

Synonyms

dopamine; 4-(2-Aminoethyl)benzene-1,2-diol; 51-61-6; 3-Hydroxytyramine; Oxytyramine; Hydroxytyramin; Dopamin; 3,4-dihydroxyphenethylamine; 4-(2-Aminoethyl)catechol; 4-(2-Aminoethyl)pyrocatechol; hydroxytyramine; 2-(3,4-dihydroxyphenyl)ethylamine; Dopamina; Dopaminum; 3,4-Dihydroxyphenylethylamine; 4-(2-Aminoethyl)-1,2-benzenediol

Frequently Asked Questions

What are the CAS number and molecular formula of dopamine?

CAS 51-61-6; molecular formula C8H11NO2; molecular weight — g/mol.

What other names is dopamine known by?

dopamine, 4-(2-Aminoethyl)benzene-1,2-diol, 51-61-6, 3-Hydroxytyramine, Oxytyramine, Hydroxytyramin.

Is dopamine classified as hazardous?

Hazard statements reported: H302, H361, H400, H410.

What are the key physical properties of dopamine?

Boiling Point: 227; Melting Point: 128; Melting Point: 128 °C; Solubility: 600.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.