二苯基(2,4,6-三甲基苯甲酰基)氧化膦（CAS 75980-60-8）：分子式 C22H21O2P、分子量 348.4。
| CAS号 | 75980-60-8 |
|---|---|
| 分子式 | C22H21O2P |
| 分子量 | 348.4 |
| LogP | 5 |
| 应用领域 | Uses: CIR ingredient: Trimethylbenzoyl Diphenylphosphine Oxide、Industry Uses: Not Known or Reasonably Ascertainable、Pigment、Photosensitive agent、Other、Tanning agents not otherwise specified、A 2021 review describes use as a photoinitiator in dental resin composites.、Consumer Uses: Solvent、Photosensitizers、Not Known or Reasonably Ascertainable、The European Commission prohibited the use of TPO in cosmetic products beginning on September 1、2025 (via the adoption of Commission Regulation (EU) 2025、877). This was the result of TPO being classified as a CMR category 1B reproductive toxicant by Commission Delegated Regulation (EU) 2024、197 under the CLP Regulation (Regulation (EC) No 1272、2008)、and this classification triggered the mandatory inclusion of TPO in Annex II (prohibited substances) of the Cosmetics Regulation via Regulation (EU) 2025、877.、Household Products: Cosmetics product ingredient: Diphenyl(2、4、6-trimethylbenzoyl)phosphine oxide (Trimethylbenzoyl diphenylphosphine oxide)、Product count: 1、U.S. Production: 2023: 1、000、000 - <2、500、000 lb、2022: 1、2021: 1、2020: 850、000 - <1、General Manufacturing Information: Printing Ink Manufacturing、Miscellaneous Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Printing and Related Support Activities、Pharmaceutical and Medicine Manufacturing、Methanone、(diphenylphosphinyl)(2、6-trimethylphenyl)-: ACTIVE |
登记用途：Uses: CIR ingredient: Trimethylbenzoyl Diphenylphosphine Oxide、Industry Uses: Not Known or Reasonably Ascertainable、Pigment、Photosensitive agent、Other、Tanning agents not otherwise specified、A 2021 review describes use as a photoinitiator in dental resin composites.、Consumer Uses: Solvent、Photosensitizers、Not Known or Reasonably Ascertainable、The European Commission prohibited the use of TPO in cosmetic products beginning on September 1、2025 (via the adoption of Commission Regulation (EU) 2025、877). This was the result of TPO being classified as a CMR category 1B reproductive toxicant by Commission Delegated Regulation (EU) 2024、197 under the CLP Regulation (Regulation (EC) No 1272、2008)、and this classification triggered the mandatory inclusion of TPO in Annex II (prohibited substances) of the Cosmetics Regulation via Regulation (EU) 2025、877.、Household Products: Cosmetics product ingredient: Diphenyl(2、4、6-trimethylbenzoyl)phosphine oxide (Trimethylbenzoyl diphenylphosphine oxide)、Product count: 1、U.S. Production: 2023: 1、000、000 - <2、500、000 lb、2022: 1、2021: 1、2020: 850、000 - <1、General Manufacturing Information: Printing Ink Manufacturing、Miscellaneous Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Printing and Related Support Activities、Pharmaceutical and Medicine Manufacturing、Methanone、(diphenylphosphinyl)(2、6-trimethylphenyl)-: ACTIVE。
二苯基(2,4,6-三甲基苯甲酰基)氧化膦 是一种化工化合物，登记 CAS 号为 75980-60-8，分子式 C22H21O2P（分子量 348.4）。
登记 CAS 号：75980-60-8
其分子式 C22H21O2P 由 22 个碳、21 个氢、2 个氧、1 个磷 组成。
别名/同义词：二苯基(2,4,6-三甲基苯甲酰基)氧化膦 · Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide
二苯基(2,4,6-三甲基苯甲酰基)氧化膦 的 CAS 登记号为 75980-60-8。
分子式 C22H21O2P，分子量 348.4。
别名/同义词：二苯基(2,4,6-三甲基苯甲酰基)氧化膦、Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide。
登记用途：Uses: CIR ingredient: Trimethylbenzoyl Diphenylphosphine Oxide、Industry Uses: Not Known or Reasonably Ascertainable、Pigment、Photosensitive agent、Other、Tanning agents not otherwise specified、A 2021 review describes use as a photoinitiator in dental resin composites.、Consumer Uses: Solvent、Photosensitizers、Not Known or Reasonably Ascertainable、The European Commission prohibited the use of TPO in cosmetic products beginning on September 1、2025 (via the adoption of Commission Regulation (EU) 2025、877). This was the result of TPO being classified as a CMR category 1B reproductive toxicant by Commission Delegated Regulation (EU) 2024、197 under the CLP Regulation (Regulation (EC) No 1272、2008)、and this classification triggered the mandatory inclusion of TPO in Annex II (prohibited substances) of the Cosmetics Regulation via Regulation (EU) 2025、877.、Household Products: Cosmetics product ingredient: Diphenyl(2、4、6-trimethylbenzoyl)phosphine oxide (Trimethylbenzoyl diphenylphosphine oxide)、Product count: 1、U.S. Production: 2023: 1、000、000 - <2、500、000 lb、2022: 1、2021: 1、2020: 850、000 - <1、General Manufacturing Information: Printing Ink Manufacturing、Miscellaneous Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Printing and Related Support Activities、Pharmaceutical and Medicine Manufacturing、Methanone、(diphenylphosphinyl)(2、6-trimethylphenyl)-: ACTIVE。
二苯基(2,4,6-三甲基苯甲酰基)氧化膦（CAS 75980-60-8）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 75980-60-8 |
|---|---|
| PubChem CID | 166480 |
| Molecular formula | C22H21O2P |
| IUPAC name | diphenylphosphoryl-(2,4,6-trimethylphenyl)methanone |
| UNII (FDA) | B9EIM2D97X |
| Molecular Weight | 348.4 |
|---|---|
| XLogP3 | 5 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 4 |
| Exact Mass | 348.12791691 |
| Monoisotopic Mass | 348.12791691 |
| Topological Polar Surface Area | 34.1 |
| Heavy Atom Count | 25 |
| Vapor Pressure | 3.045 x 10-6 Pa at 25 degrees C |
|---|---|
| pH | 4 to 5 |
75980-60-8; Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide; Phosphine oxide, diphenyl(2,4,6-trimethylbenzoyl)-; DTXSID4052502; EINECS 278-355-8; B9EIM2D97X; 2,4,6-trimethylbenzoyl diphenylphosphine oxide; trimethylbenzoyl diphenylphosphine oxide; CHIVACURE TPO; DOUBLECURE TPO; ADDITOL TPO; GENOCURE TPO; Methanone, (diphenylphosphinyl)(2,4,6-trimethylphenyl)-; DTXCID8031075; EC 278-355-8; (2,4,6-trimethylbenzoyl)diphenylphosphine oxide
| Regulatory & Food Contact | CIR / INCI: Cosmetic ingredients (Trimethylbenzoyl Diphenylphosphine Oxide) -> CIR (Cosmetic Ingredient Review) |
|---|---|
| GHS notification summary | 0.4% (13 / 3088) |
| GHS notification summary | 0.4% (13 / 3088) |
|---|---|
| Reported hazard statements | H317, H361 (95.3%), H411 (87%) |
H317: May cause an allergic skin reaction [Warning Sensitization, Skin]
H360Fd: May damage fertility; Suspected of damaging the unborn child [Danger Reproductive toxicity]
Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide · CAS 75980-60-8 · C22H21O2P. UNII B9EIM2D97X. Vapor Pressure: 3.045 x 10-6 Pa at 25 degrees C; pH: 4 to 5.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide