cyclobenzaprine (CAS 303-53-7) — formula C20H21N, molecular weight 275.4; category organic chemicals.
| CAS Number | 303-53-7 |
|---|---|
| Molecular Formula | C20H21N |
| Molecular Weight | 275.4 |
| Melting Point | 217 |
| Boiling Point | BP: 175-180 °C at 1 atm |
| LogP | 5.2 |
| Applications | Uses: MEDICATION, Antidepressive Agents, Tricyclic, Muscle Relaxants, Central, Tranquilizing Agents, Use (kg) in USA (2002): 276, Consumption (g per capita) in the USA (2002): 0.000978, Calculated removal (%): 91.6, Use Classification: Pharmaceuticals, Methods of Manufacturing: Cyclobenzaprine may be synthesized by Grignard addition of alpha-dimethylaminopropylmagnesium chloride to 10, 11-dihydro-5H-dibenzo[a, d]cycloheptene-5-one, followed by elimination of water from the resulting tertiary carbinol., Formulations, Preparations: Capsules, extended-release, oral: 15 mg, 30 mg Amrix (Teva), Tablets, oral: 7.5 mg Fexmid (Shionogi), Table: Cyclobenzaprine Hydrochloride Preparations [Table#8318] |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, Antidepressive Agents, Tricyclic, Muscle Relaxants, Central, Tranquilizing Agents, Use (kg) in USA (2002): 276, Consumption (g per capita) in the USA (2002): 0.000978, Calculated removal (%): 91.6, Use Classification: Pharmaceuticals, Methods of Manufacturing: Cyclobenzaprine may be synthesized by Grignard addition of alpha-dimethylaminopropylmagnesium chloride to 10, 11-dihydro-5H-dibenzo[a, d]cycloheptene-5-one, followed by elimination of water from the resulting tertiary carbinol., Formulations, Preparations: Capsules, extended-release, oral: 15 mg, 30 mg Amrix (Teva), Tablets, oral: 7.5 mg Fexmid (Shionogi), Table: Cyclobenzaprine Hydrochloride Preparations [Table#8318].
cyclobenzaprine is a carbon-based organic compound with CAS registry number 303-53-7 and molecular formula C20H21N (molecular weight 275.4), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 303-53-7
Its molecular formula C20H21N comprises 20 C, 21 H, 1 N atoms.
Also known as: cyclobenzaprine · 环苯扎林
Category: organic chemicals
The CAS registry number of cyclobenzaprine is 303-53-7.
Molecular formula C20H21N, molecular weight 275.4.
It is also registered under: cyclobenzaprine, 环苯扎林.
Recorded applications: Uses: MEDICATION, Antidepressive Agents, Tricyclic, Muscle Relaxants, Central, Tranquilizing Agents, Use (kg) in USA (2002): 276, Consumption (g per capita) in the USA (2002): 0.000978, Calculated removal (%): 91.6, Use Classification: Pharmaceuticals, Methods of Manufacturing: Cyclobenzaprine may be synthesized by Grignard addition of alpha-dimethylaminopropylmagnesium chloride to 10, 11-dihydro-5H-dibenzo[a, d]cycloheptene-5-one, followed by elimination of water from the resulting tertiary carbinol., Formulations, Preparations: Capsules, extended-release, oral: 15 mg, 30 mg Amrix (Teva), Tablets, oral: 7.5 mg Fexmid (Shionogi), Table: Cyclobenzaprine Hydrochloride Preparations [Table#8318].
Category: Organic Chemicals.
Independent reference data for cyclobenzaprine (CAS 303-53-7), compiled from public chemistry databases.
| CAS Registry Number | 303-53-7 |
|---|---|
| PubChem CID | 2895 |
| Molecular formula | C20H21N |
| IUPAC name | N,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine |
| UNII (FDA) | 69O5WQQ5TI |
| Molecular Weight | 275.4 |
|---|---|
| XLogP3 | 5.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 3 |
| Exact Mass | 275.167399674 |
| Monoisotopic Mass | 275.167399674 |
| Topological Polar Surface Area | 3.2 |
| Heavy Atom Count | 21 |
| Boiling Point | BP: 175-180 °C at 1 atm |
|---|---|
| Melting Point | 217 |
| Solubility | 6.89e-03 g/L |
| LogP | 5.2 |
| LogP | 4.81 |
| Dissociation Constants | 9.69 |
| Dissociation Constants | 8.241 |
| Dissociation Constants | 8.47 |
cyclobenzaprine; 303-53-7; Proheptatriene; Proheptatrien; Ciclobenzaprina; Proeptatriene; Lisseril; Fexmid; Cyclobenzaprinum; 10,11-Dehydroamitriptyline; 3-(5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine; 69O5WQQ5TI; MK-130; MK-130 (AS THE BASE); 5-(3-Dimetilaminopropiliden)-5H-dibenzo-(a,d)-ciclopentene; 1-Propanamine, 3-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-
| Reported hazard statements | H301, H312, H332 |
|---|
Reported as not meeting GHS hazard criteria by 1 of 1 companies. For more detailed information, please visit ECHA C&L website.
H301: Toxic if swallowed [Danger Acute toxicity, oral]
cyclobenzaprine · CAS 303-53-7 · C20H21N. UNII 69O5WQQ5TI. Boiling Point: BP: 175-180 °C at 1 atm; Melting Point: 217; Solubility: 6.89e-03 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 环苯扎林