雪卡毒素（CAS 11050-21-8）：分子式 C60H86O19、分子量 1111.3。
| CAS号 | 11050-21-8 |
|---|---|
| 分子式 | C60H86O19 |
| 分子量 | 1111.3 |
| LogP | 2.5 |
| 应用领域 | Uses: A toxin found in a variety of fish produced by the dinoflagellate Gambierdiscus spp、[Merck Index]、It is a marine toxin、found in reef fish (L994).、General Manufacturing Information: Ciguatoxin and maitotoxin have been isolated from the biodetritus layer of coral reefs、from the dinoflagellate Gambierdiscus toxicus collected from seawater、and from axenic cultures of G. toxicus.、Family of lipid soluble polyether toxins responsible for ciguatera food poisoning、structural variations are associated with the oceanic region from which the dinoflagellate originates.、Ciguatoxins、Toxin profiles of representative ciguatera species caught at different locations of Japan were investigated in fish flesh by high-performance liquid chromatography tandem mass spectrometry (LC-MS、MS) analysis. Identification and quantification of 16 toxins were facilitated by the use of 14 reference toxins prepared by either synthesis or isolation from natural sources and the previous LC-MS data thereof. Sodium adduct ions [M + Na]+ were used as parent and product ions. Distinct regional differences were unveiled: ciguatoxin-1B type toxins were found in snappers and groupers from Okinawa、ciguatoxin-3C type toxins were found in a spotted knifejaw、Oplegnathus punctatus、from Miyazaki located 730 km north of Okinawa、and both types of toxins were found in a red snapper、Lutjanus bohar、from Minamitorishima (Marcus) Island. Twelve toxins were identified in a dinoflagellate、Gambierdiscus toxicus、collected as the primary toxin source in French Polynesia. Occurrence of M-seco-toxins in fish and oxidized toxins in the dinoflagellate was confirmed for the first time. The present LC-MS、MS method is rapid、specific、and accurate. It not only outperforms the currently employed mouse bioassays but also enables the study of the toxin dynamics during the food chain transmission. |
登记用途：Uses: A toxin found in a variety of fish produced by the dinoflagellate Gambierdiscus spp、[Merck Index]、It is a marine toxin、found in reef fish (L994).、General Manufacturing Information: Ciguatoxin and maitotoxin have been isolated from the biodetritus layer of coral reefs、from the dinoflagellate Gambierdiscus toxicus collected from seawater、and from axenic cultures of G. toxicus.、Family of lipid soluble polyether toxins responsible for ciguatera food poisoning、structural variations are associated with the oceanic region from which the dinoflagellate originates.、Ciguatoxins、Toxin profiles of representative ciguatera species caught at different locations of Japan were investigated in fish flesh by high-performance liquid chromatography tandem mass spectrometry (LC-MS、MS) analysis. Identification and quantification of 16 toxins were facilitated by the use of 14 reference toxins prepared by either synthesis or isolation from natural sources and the previous LC-MS data thereof. Sodium adduct ions [M + Na]+ were used as parent and product ions. Distinct regional differences were unveiled: ciguatoxin-1B type toxins were found in snappers and groupers from Okinawa、ciguatoxin-3C type toxins were found in a spotted knifejaw、Oplegnathus punctatus、from Miyazaki located 730 km north of Okinawa、and both types of toxins were found in a red snapper、Lutjanus bohar、from Minamitorishima (Marcus) Island. Twelve toxins were identified in a dinoflagellate、Gambierdiscus toxicus、collected as the primary toxin source in French Polynesia. Occurrence of M-seco-toxins in fish and oxidized toxins in the dinoflagellate was confirmed for the first time. The present LC-MS、MS method is rapid、specific、and accurate. It not only outperforms the currently employed mouse bioassays but also enables the study of the toxin dynamics during the food chain transmission.。
雪卡毒素 是一种化工化合物，登记 CAS 号为 11050-21-8，分子式 C60H86O19（分子量 1111.3）。
登记 CAS 号：11050-21-8
其分子式 C60H86O19 由 60 个碳、86 个氢、19 个氧 组成。
别名/同义词：雪卡毒素 · Ciguatoxin
雪卡毒素 的 CAS 登记号为 11050-21-8。
分子式 C60H86O19，分子量 1111.3。
别名/同义词：雪卡毒素、Ciguatoxin。
登记用途：Uses: A toxin found in a variety of fish produced by the dinoflagellate Gambierdiscus spp、[Merck Index]、It is a marine toxin、found in reef fish (L994).、General Manufacturing Information: Ciguatoxin and maitotoxin have been isolated from the biodetritus layer of coral reefs、from the dinoflagellate Gambierdiscus toxicus collected from seawater、and from axenic cultures of G. toxicus.、Family of lipid soluble polyether toxins responsible for ciguatera food poisoning、structural variations are associated with the oceanic region from which the dinoflagellate originates.、Ciguatoxins、Toxin profiles of representative ciguatera species caught at different locations of Japan were investigated in fish flesh by high-performance liquid chromatography tandem mass spectrometry (LC-MS、MS) analysis. Identification and quantification of 16 toxins were facilitated by the use of 14 reference toxins prepared by either synthesis or isolation from natural sources and the previous LC-MS data thereof. Sodium adduct ions [M + Na]+ were used as parent and product ions. Distinct regional differences were unveiled: ciguatoxin-1B type toxins were found in snappers and groupers from Okinawa、ciguatoxin-3C type toxins were found in a spotted knifejaw、Oplegnathus punctatus、from Miyazaki located 730 km north of Okinawa、and both types of toxins were found in a red snapper、Lutjanus bohar、from Minamitorishima (Marcus) Island. Twelve toxins were identified in a dinoflagellate、Gambierdiscus toxicus、collected as the primary toxin source in French Polynesia. Occurrence of M-seco-toxins in fish and oxidized toxins in the dinoflagellate was confirmed for the first time. The present LC-MS、MS method is rapid、specific、and accurate. It not only outperforms the currently employed mouse bioassays but also enables the study of the toxin dynamics during the food chain transmission.。
雪卡毒素（CAS 11050-21-8）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 11050-21-8 |
|---|---|
| PubChem CID | 5311333 |
| 分子式 | C60H86O19 |
| UNII（FDA） | 2UKQ3B7696 |
| Molecular Weight | 1111.3 |
|---|---|
| XLogP3 | 2.5 |
| Hydrogen Bond Donor Count | 6 |
| Hydrogen Bond Acceptor Count | 19 |
| Rotatable Bond Count | 3 |
| Exact Mass | 1110.57633051 |
| Monoisotopic Mass | 1110.57633051 |
| Topological Polar Surface Area | 241 |
| Heavy Atom Count | 79 |
Ciguatoxin CTX 1; CIGUATOXIN; 11050-21-8; Ciguatoxins; Ciguatoxin 1; CTX 1; P-CTX 1; 2UKQ3B7696; DTXSID40880000; RefChem:388885; CHEBI:61275; DTXCID401763388; CTX-1; Pacific ciguatoxin 1; ciguatoxin-1; Ciguatoxin I
雪卡毒素 · CAS 11050-21-8 · C60H86O19. UNII 2UKQ3B7696.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Ciguatoxin