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CI 75300

CAS 94875-80-6C21H20O6MW 368.4

CI 75300 (CAS 94875-80-6) — formula C21H20O6, molecular weight 368.4; category organic chemicals.

Product Overview

CAS Number94875-80-6
Molecular FormulaC21H20O6
Molecular Weight368.4
Melting Point356 to 361 °F (NTP, 1992)
LogP3.2
ApplicationsUses: Natural dye from the root of Curcuma longa, [Merck Index] Used for preparing curcuma paper, detecting boron, dyeing and flavoring food, dyeing fabrics (cotton, wool, and silk), and coloring oils and waxes, Also used as a biological stain and acid-base indicator, [HSDB] Thought to be the most bio-active component in tumeric, [REPROTOX], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], For preparing curcuma paper, pH range 8-9. In the detection of boron., Analytical reagent, food dye, biological stain. As an acid-base indicator it is brownish-red with alkalies, yellow with acids (pH range 7.4-8.6), also as an indicator for boron., Flavoring and coloring agent in food-as turmeric, boron indicator, stain in microscopy, alkali indicator, coloring agent for oils, waxes, & textiles, Curcumin is a natural polyphenol product derived from the rhizome of the Curcuma longa. In vivo and in vitro studies have uncovered many important bioactivities of curcumin, such as antioxidant activity, inducing cell apoptosis, inhibiting cell proliferation, anti-cell adhesion and motility, anti-angiogenesis and anti-microbe properties. Based on these functions, curcumin has been used in clinical trials on various inflammatory diseases and cancers. In the future, it will be necessary to focus attention partly on the clinical application of curcumin in neurodegenerative diseases, cardiovascular diseases and diabetes, because many experiments have clarified the potential value of curcumin in these areas..., For more Uses (Complete) data for CURCUMIN (6 total), please visit the HSDB record page., Use Classification: Food additives, Food Additives -> COLOUR -> JECFA Functional Classes, Flavouring Agent -> FLAVOURING_AGENTFood Additives -> COLOUR -> JECFA Functional Classes, Cosmetics -> Cosmetic colorant, Household Products: Information on 3 consumer products that contain Curcumin in the following categories is provided:, • Auto Products, • Personal Care, Methods of Manufacturing: Occurs naturally in the root of the herb curcuma longa (turmeric), isolation by steam distillation, The essential oil of Curcuma longa is obtained by steam distillation, with yields ranging between 1.3 and 5.5%. ... The oil contains, in addition to turmerone (~60%), free acids, cineol, borneol, zingerone, phellandrene, and 3 to 4% coloring matter (curcumin)., Essential oil of Curcuma longa, Production: Stieglitz, Horn, German patent 859145 (1952 to Hoechst), Formulations, Preparations: Derivatives: tincture (20% in 60% ethanol), fluid extract, & oleoresin., Deriv of turmeric, U.S. Production: (1976) 6.4X10+8 G-MIN USE IN FOODS-AS TURMERIC, (1979) No Data, U.S. Imports: (1977) 1.12X10+9 GRAMS AS TUMERIC, (1979) 1.54X10+9 GRAMS AS TUMERIC, U.S. Exports: (1977) No Data, General Manufacturing Information: 1, 6-Heptadiene-3, 5-dione, 1, 7-bis(4-hydroxy-3-methoxyphenyl)-, (1E, 6E)-: ACTIVE, ..., Curcuma longa, is originally from southern Asia and is widespread throughout India, Malaysia, Ceylon and Japan. It is perennial herb whose rhizome yields ... climbing stalks with leaves only or with leaves and flowers. Reproduction occurs through the splitting of the rhizome, which is the only part used (dried rhizome as is or after previously boiling in water)., Turmeric yields about 5% volatile oil... oil contains alc, turmerol, & ketone, curcumone. About 59%...consists of mixt of alicyclic sesquiterpene ketone, turmerone, C15H22O, & aromatic ketone, arturmerone C15H20O. Other organic compd incl d-alpha-phellandrene, d-sabinene, zingiberene, cineole & borneol., Turmeric, Curcumin assists in identification of turmeric starch. Yellow, pasty masses of starch become reddish-brown with sodium, potassium, & ammonium hydroxides, crimson with concentrated sulfuric acid., Curcumin showed bacteriostatic activity against staphylococcus., For more General Manufacturing Information (Complete) data for CURCUMIN (8 total)
CategoryOrganic Chemicals

Applications

Documented applications: Uses: Natural dye from the root of Curcuma longa, [Merck Index] Used for preparing curcuma paper, detecting boron, dyeing and flavoring food, dyeing fabrics (cotton, wool, and silk), and coloring oils and waxes, Also used as a biological stain and acid-base indicator, [HSDB] Thought to be the most bio-active component in tumeric, [REPROTOX], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], For preparing curcuma paper, pH range 8-9. In the detection of boron., Analytical reagent, food dye, biological stain. As an acid-base indicator it is brownish-red with alkalies, yellow with acids (pH range 7.4-8.6), also as an indicator for boron., Flavoring and coloring agent in food-as turmeric, boron indicator, stain in microscopy, alkali indicator, coloring agent for oils, waxes, & textiles, Curcumin is a natural polyphenol product derived from the rhizome of the Curcuma longa. In vivo and in vitro studies have uncovered many important bioactivities of curcumin, such as antioxidant activity, inducing cell apoptosis, inhibiting cell proliferation, anti-cell adhesion and motility, anti-angiogenesis and anti-microbe properties. Based on these functions, curcumin has been used in clinical trials on various inflammatory diseases and cancers. In the future, it will be necessary to focus attention partly on the clinical application of curcumin in neurodegenerative diseases, cardiovascular diseases and diabetes, because many experiments have clarified the potential value of curcumin in these areas..., For more Uses (Complete) data for CURCUMIN (6 total), please visit the HSDB record page., Use Classification: Food additives, Food Additives -> COLOUR -> JECFA Functional Classes, Flavouring Agent -> FLAVOURING_AGENTFood Additives -> COLOUR -> JECFA Functional Classes, Cosmetics -> Cosmetic colorant, Household Products: Information on 3 consumer products that contain Curcumin in the following categories is provided:, • Auto Products, • Personal Care, Methods of Manufacturing: Occurs naturally in the root of the herb curcuma longa (turmeric), isolation by steam distillation, The essential oil of Curcuma longa is obtained by steam distillation, with yields ranging between 1.3 and 5.5%. ... The oil contains, in addition to turmerone (~60%), free acids, cineol, borneol, zingerone, phellandrene, and 3 to 4% coloring matter (curcumin)., Essential oil of Curcuma longa, Production: Stieglitz, Horn, German patent 859145 (1952 to Hoechst), Formulations, Preparations: Derivatives: tincture (20% in 60% ethanol), fluid extract, & oleoresin., Deriv of turmeric, U.S. Production: (1976) 6.4X10+8 G-MIN USE IN FOODS-AS TURMERIC, (1979) No Data, U.S. Imports: (1977) 1.12X10+9 GRAMS AS TUMERIC, (1979) 1.54X10+9 GRAMS AS TUMERIC, U.S. Exports: (1977) No Data, General Manufacturing Information: 1, 6-Heptadiene-3, 5-dione, 1, 7-bis(4-hydroxy-3-methoxyphenyl)-, (1E, 6E)-: ACTIVE, ..., Curcuma longa, is originally from southern Asia and is widespread throughout India, Malaysia, Ceylon and Japan. It is perennial herb whose rhizome yields ... climbing stalks with leaves only or with leaves and flowers. Reproduction occurs through the splitting of the rhizome, which is the only part used (dried rhizome as is or after previously boiling in water)., Turmeric yields about 5% volatile oil... oil contains alc, turmerol, & ketone, curcumone. About 59%...consists of mixt of alicyclic sesquiterpene ketone, turmerone, C15H22O, & aromatic ketone, arturmerone C15H20O. Other organic compd incl d-alpha-phellandrene, d-sabinene, zingiberene, cineole & borneol., Turmeric, Curcumin assists in identification of turmeric starch. Yellow, pasty masses of starch become reddish-brown with sodium, potassium, & ammonium hydroxides, crimson with concentrated sulfuric acid., Curcumin showed bacteriostatic activity against staphylococcus., For more General Manufacturing Information (Complete) data for CURCUMIN (8 total).

Technical Profile

What this product is

CI 75300 is a carbon-based organic compound with CAS registry number 94875-80-6 and molecular formula C21H20O6 (molecular weight 368.4), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 94875-80-6

Its molecular formula C21H20O6 comprises 21 C, 20 H, 6 O atoms.

Also known as: CI 75300 · 姜黄素(合成物)

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of CI 75300?

The CAS registry number of CI 75300 is 94875-80-6.

What is the molecular formula and molecular weight of CI 75300?

Molecular formula C21H20O6, molecular weight 368.4.

What other names is CI 75300 known by?

It is also registered under: CI 75300, 姜黄素(合成物).

What are the documented applications of CI 75300?

Recorded applications: Uses: Natural dye from the root of Curcuma longa, [Merck Index] Used for preparing curcuma paper, detecting boron, dyeing and flavoring food, dyeing fabrics (cotton, wool, and silk), and coloring oils and waxes, Also used as a biological stain and acid-base indicator, [HSDB] Thought to be the most bio-active component in tumeric, [REPROTOX], Textiles (Printing, Dyeing, or Finishing) [Category: Industry], For preparing curcuma paper, pH range 8-9. In the detection of boron., Analytical reagent, food dye, biological stain. As an acid-base indicator it is brownish-red with alkalies, yellow with acids (pH range 7.4-8.6), also as an indicator for boron., Flavoring and coloring agent in food-as turmeric, boron indicator, stain in microscopy, alkali indicator, coloring agent for oils, waxes, & textiles, Curcumin is a natural polyphenol product derived from the rhizome of the Curcuma longa. In vivo and in vitro studies have uncovered many important bioactivities of curcumin, such as antioxidant activity, inducing cell apoptosis, inhibiting cell proliferation, anti-cell adhesion and motility, anti-angiogenesis and anti-microbe properties. Based on these functions, curcumin has been used in clinical trials on various inflammatory diseases and cancers. In the future, it will be necessary to focus attention partly on the clinical application of curcumin in neurodegenerative diseases, cardiovascular diseases and diabetes, because many experiments have clarified the potential value of curcumin in these areas..., For more Uses (Complete) data for CURCUMIN (6 total), please visit the HSDB record page., Use Classification: Food additives, Food Additives -> COLOUR -> JECFA Functional Classes, Flavouring Agent -> FLAVOURING_AGENTFood Additives -> COLOUR -> JECFA Functional Classes, Cosmetics -> Cosmetic colorant, Household Products: Information on 3 consumer products that contain Curcumin in the following categories is provided:, • Auto Products, • Personal Care, Methods of Manufacturing: Occurs naturally in the root of the herb curcuma longa (turmeric), isolation by steam distillation, The essential oil of Curcuma longa is obtained by steam distillation, with yields ranging between 1.3 and 5.5%. ... The oil contains, in addition to turmerone (~60%), free acids, cineol, borneol, zingerone, phellandrene, and 3 to 4% coloring matter (curcumin)., Essential oil of Curcuma longa, Production: Stieglitz, Horn, German patent 859145 (1952 to Hoechst), Formulations, Preparations: Derivatives: tincture (20% in 60% ethanol), fluid extract, & oleoresin., Deriv of turmeric, U.S. Production: (1976) 6.4X10+8 G-MIN USE IN FOODS-AS TURMERIC, (1979) No Data, U.S. Imports: (1977) 1.12X10+9 GRAMS AS TUMERIC, (1979) 1.54X10+9 GRAMS AS TUMERIC, U.S. Exports: (1977) No Data, General Manufacturing Information: 1, 6-Heptadiene-3, 5-dione, 1, 7-bis(4-hydroxy-3-methoxyphenyl)-, (1E, 6E)-: ACTIVE, ..., Curcuma longa, is originally from southern Asia and is widespread throughout India, Malaysia, Ceylon and Japan. It is perennial herb whose rhizome yields ... climbing stalks with leaves only or with leaves and flowers. Reproduction occurs through the splitting of the rhizome, which is the only part used (dried rhizome as is or after previously boiling in water)., Turmeric yields about 5% volatile oil... oil contains alc, turmerol, & ketone, curcumone. About 59%...consists of mixt of alicyclic sesquiterpene ketone, turmerone, C15H22O, & aromatic ketone, arturmerone C15H20O. Other organic compd incl d-alpha-phellandrene, d-sabinene, zingiberene, cineole & borneol., Turmeric, Curcumin assists in identification of turmeric starch. Yellow, pasty masses of starch become reddish-brown with sodium, potassium, & ammonium hydroxides, crimson with concentrated sulfuric acid., Curcumin showed bacteriostatic activity against staphylococcus., For more General Manufacturing Information (Complete) data for CURCUMIN (8 total).

Which category does CI 75300 belong to?

Category: Organic Chemicals.

PubChem Public Data

Independent reference data for CI 75300 (CAS 94875-80-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS 号94875-80-6
PubChem CID969516
分子式C21H20O6
IUPAC 名称(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
UNII(FDA)IT942ZTH98

Computed descriptors

Molecular Weight368.4
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Exact Mass368.12598835
Monoisotopic Mass368.12598835
Topological Polar Surface Area93.1
Heavy Atom Count27

Physicochemical values on record

Melting Point356 to 361 °F (NTP, 1992)
Melting Point183
Melting Point179 °C-182 °C
Melting Point183 °C

Synonyms and trade names

curcumin; 458-37-7; Diferuloylmethane; Natural yellow 3; Kacha haldi; Curcumin I; Curcuma; Haldar; Indian saffron; Gelbwurz; Yellow Ginger; (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione; Souchet; Haidr; Halad; Halud

Regulatory listings held on file

法规与食品接触COLOUR: Food Additives
FLAVOURING_AGENTFood Additives -> COLOUR: Flavouring Agent
旨在用作酸奶、营养棒、冰沙和医疗食品中的营养补充剂,其含量为 i
Scientific procedures
FDA has no questions (in PDF)
DolCas Biotech, LLC
GHS 通报统计7.4% (12 / 163)

GHS hazard classification

GHS 通报统计7.4% (12 / 163)
已通报的危害声明H315 (92%), H319 (92.6%), H335 (91.4%)

What the public record says

姜黄素(合成物) · CAS 94875-80-6 · C21H20O6. UNII IT942ZTH98. Melting Point: 356 to 361 °F (NTP, 1992); Melting Point: 183; Melting Point: 179 °C-182 °C.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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