氯化胆碱（CAS 67-48-1）：分子式 C5H14ClNO、分子量 139.62。
| CAS号 | 67-48-1 |
|---|---|
| 分子式 | C5H14ClNO |
| 分子量 | 139.62 |
| 熔点 | 305 °C (decomposes) |
| LogP | -5.16 |
| 应用领域 | Uses: CIR ingredient: Choline Chloride、Therap cat: lipotropic、Therap cat (vet): Nutritional factor. Dietary source of choline (lipotropic factor) in poultry.、MEDICATION、MEDICATION (VET)、MEDICATION (VET): Animal feed additive derived from agricultural waste or made synthetically. Available as 50% dry feed-grade & 70% soln.、Use (kg、approx.) in Germany (2009): >750、Consumption (g per capita、approx.) in Germany (2009): 0.00916、Calculated removal (%): 92.1、Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Processing aids、specific to petroleum production、Abrasives、Soil amendments (fertilizers)、Other、Consumer Uses: Soil amendments (fertilizers)、Not Known or Reasonably Ascertainable、Methods of Manufacturing: REACTION OF TRIMETHYLAMINE AND CONCENTRATED HYDROCHLORIC ACID、FOLLOWED BY TREATMENT WITH ETHYLENE OXIDE UNDER PRESSURE、Klein、Kapp、US patent 2、623、901 (1952 to Nopco Chemical). Polymorphism: Collin、J Am Chem Soc 79、6086 (1957).、Chloine is normally produced by the reaction of trimethylamine、ethylene oxide、and water. Its chloride can be produced by the reaction of trimethylene with chlorohydrin.、Formulations、Preparations: FORMS AVAILABLE GENERICALLY: TABLETS 250 MG (CHOLINE BITARTRATES)、POWDER (CHOLINE CHLORIDE、CHOLINE DIHYDROGEN CITRATE).、U.S. Production: 2023: 5、000、000 - <10、000 lb、2022: 5、2021: 5、2020: 10、000 - <50、(1972) 2.47X10+10 GRAMS (MED & TECH GRADE)、(1975) 1.76X10+10 GRAMS (ALL GRADES)、Ethanaminium、2-hydroxy-N、N、N-trimethyl-、chloride is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#2627]、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) NEGLIGIBLE、General Manufacturing Information: Oil and Gas Drilling、Extraction、and Support activities、Agriculture、Forestry、Fishing and Hunting、chloride (1:1): ACTIVE、A SELECTED FOOD ADDITIVE CLASSIFIED AS A NUTRIENT AND DIETARY SUPPLEMENT.、FROM TABLE、QUALITATIVELY CHOLINE HAS THE SAME PHARMACOLOGICAL ACTIONS AS DOES ACETYLCHOLINE、BUT IT IS FAR LESS ACTIVE.、CHOLINE、SINCE HUMAN BREAST MILK CONTAINS 7 MG CHOLINE、100 KCAL、COMMITTEE ON NUTRITION OF AMERICAN ACADEMY OF PEDIATRICS (1976) RECOMMENDS THE FORTIFICATION OF INFANT FORMULAS TO THIS LEVEL.、CHOLINE IS NOT @ PRESENT AN OFFICIAL DRUG. HOWEVER、PREPN OF...CHOLINE CHLORIDE ARE AVAILABLE.、... The dominating industrial process、for choline、is reacting ethylene oxide with trimethylamine and water、or an acid if one of its salts is desired、in a batch or continuous manufacturing process. |
登记用途：Uses: CIR ingredient: Choline Chloride、Therap cat: lipotropic、Therap cat (vet): Nutritional factor. Dietary source of choline (lipotropic factor) in poultry.、MEDICATION、MEDICATION (VET)、MEDICATION (VET): Animal feed additive derived from agricultural waste or made synthetically. Available as 50% dry feed-grade & 70% soln.、Use (kg、approx.) in Germany (2009): >750、Consumption (g per capita、approx.) in Germany (2009): 0.00916、Calculated removal (%): 92.1、Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Processing aids、specific to petroleum production、Abrasives、Soil amendments (fertilizers)、Other、Consumer Uses: Soil amendments (fertilizers)、Not Known or Reasonably Ascertainable、Methods of Manufacturing: REACTION OF TRIMETHYLAMINE AND CONCENTRATED HYDROCHLORIC ACID、FOLLOWED BY TREATMENT WITH ETHYLENE OXIDE UNDER PRESSURE、Klein、Kapp、US patent 2、623、901 (1952 to Nopco Chemical). Polymorphism: Collin、J Am Chem Soc 79、6086 (1957).、Chloine is normally produced by the reaction of trimethylamine、ethylene oxide、and water. Its chloride can be produced by the reaction of trimethylene with chlorohydrin.、Formulations、Preparations: FORMS AVAILABLE GENERICALLY: TABLETS 250 MG (CHOLINE BITARTRATES)、POWDER (CHOLINE CHLORIDE、CHOLINE DIHYDROGEN CITRATE).、U.S. Production: 2023: 5、000、000 - <10、000 lb、2022: 5、2021: 5、2020: 10、000 - <50、(1972) 2.47X10+10 GRAMS (MED & TECH GRADE)、(1975) 1.76X10+10 GRAMS (ALL GRADES)、Ethanaminium、2-hydroxy-N、N、N-trimethyl-、chloride is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#2627]、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) NEGLIGIBLE、General Manufacturing Information: Oil and Gas Drilling、Extraction、and Support activities、Agriculture、Forestry、Fishing and Hunting、chloride (1:1): ACTIVE、A SELECTED FOOD ADDITIVE CLASSIFIED AS A NUTRIENT AND DIETARY SUPPLEMENT.、FROM TABLE、QUALITATIVELY CHOLINE HAS THE SAME PHARMACOLOGICAL ACTIONS AS DOES ACETYLCHOLINE、BUT IT IS FAR LESS ACTIVE.、CHOLINE、SINCE HUMAN BREAST MILK CONTAINS 7 MG CHOLINE、100 KCAL、COMMITTEE ON NUTRITION OF AMERICAN ACADEMY OF PEDIATRICS (1976) RECOMMENDS THE FORTIFICATION OF INFANT FORMULAS TO THIS LEVEL.、CHOLINE IS NOT @ PRESENT AN OFFICIAL DRUG. HOWEVER、PREPN OF...CHOLINE CHLORIDE ARE AVAILABLE.、... The dominating industrial process、for choline、is reacting ethylene oxide with trimethylamine and water、or an acid if one of its salts is desired、in a batch or continuous manufacturing process.。
氯化胆碱 是一种化工化合物，登记 CAS 号为 67-48-1，分子式 C5H14ClNO（分子量 139.62）。
登记 CAS 号：67-48-1
其分子式 C5H14ClNO 由 5 个碳、14 个氢、1 个氯、1 个氮、1 个氧 组成。
别名/同义词：氯化胆碱 · Choline chloride · Choline Chloride FCC
氯化胆碱 的 CAS 登记号为 67-48-1。
分子式 C5H14ClNO，分子量 139.62。
别名/同义词：氯化胆碱、Choline chloride、Choline Chloride FCC。
登记用途：Uses: CIR ingredient: Choline Chloride、Therap cat: lipotropic、Therap cat (vet): Nutritional factor. Dietary source of choline (lipotropic factor) in poultry.、MEDICATION、MEDICATION (VET)、MEDICATION (VET): Animal feed additive derived from agricultural waste or made synthetically. Available as 50% dry feed-grade & 70% soln.、Use (kg、approx.) in Germany (2009): >750、Consumption (g per capita、approx.) in Germany (2009): 0.00916、Calculated removal (%): 92.1、Use Classification: Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Processing aids、specific to petroleum production、Abrasives、Soil amendments (fertilizers)、Other、Consumer Uses: Soil amendments (fertilizers)、Not Known or Reasonably Ascertainable、Methods of Manufacturing: REACTION OF TRIMETHYLAMINE AND CONCENTRATED HYDROCHLORIC ACID、FOLLOWED BY TREATMENT WITH ETHYLENE OXIDE UNDER PRESSURE、Klein、Kapp、US patent 2、623、901 (1952 to Nopco Chemical). Polymorphism: Collin、J Am Chem Soc 79、6086 (1957).、Chloine is normally produced by the reaction of trimethylamine、ethylene oxide、and water. Its chloride can be produced by the reaction of trimethylene with chlorohydrin.、Formulations、Preparations: FORMS AVAILABLE GENERICALLY: TABLETS 250 MG (CHOLINE BITARTRATES)、POWDER (CHOLINE CHLORIDE、CHOLINE DIHYDROGEN CITRATE).、U.S. Production: 2023: 5、000、000 - <10、000 lb、2022: 5、2021: 5、2020: 10、000 - <50、(1972) 2.47X10+10 GRAMS (MED & TECH GRADE)、(1975) 1.76X10+10 GRAMS (ALL GRADES)、Ethanaminium、2-hydroxy-N、N、N-trimethyl-、chloride is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#2627]、U.S. Imports: (1972) No Data、(1975) No Data、U.S. Exports: (1972) NEGLIGIBLE、General Manufacturing Information: Oil and Gas Drilling、Extraction、and Support activities、Agriculture、Forestry、Fishing and Hunting、chloride (1:1): ACTIVE、A SELECTED FOOD ADDITIVE CLASSIFIED AS A NUTRIENT AND DIETARY SUPPLEMENT.、FROM TABLE、QUALITATIVELY CHOLINE HAS THE SAME PHARMACOLOGICAL ACTIONS AS DOES ACETYLCHOLINE、BUT IT IS FAR LESS ACTIVE.、CHOLINE、SINCE HUMAN BREAST MILK CONTAINS 7 MG CHOLINE、100 KCAL、COMMITTEE ON NUTRITION OF AMERICAN ACADEMY OF PEDIATRICS (1976) RECOMMENDS THE FORTIFICATION OF INFANT FORMULAS TO THIS LEVEL.、CHOLINE IS NOT @ PRESENT AN OFFICIAL DRUG. HOWEVER、PREPN OF...CHOLINE CHLORIDE ARE AVAILABLE.、... The dominating industrial process、for choline、is reacting ethylene oxide with trimethylamine and water、or an acid if one of its salts is desired、in a batch or continuous manufacturing process.。
氯化胆碱（CAS 67-48-1）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 67-48-1 |
|---|---|
| PubChem CID | 6209 |
| 分子式 | C5H14ClNO |
| 分子量 | 139.08 g/mol |
| IUPAC 名称 | 2-hydroxyethyl(trimethyl)azanium chloride |
| InChIKey | SGMZJAMFUVOLNK-UHFFFAOYSA-M |
| UNII（FDA） | 45I14D8O27 |
| ChEBI 编号 | CHEBI:133341 |
| FEMA 编号 | 4500 |
| JECFA 编号 | 2003 |
| Molecular Weight | 139.62 |
|---|---|
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 139.0763918 |
| Monoisotopic Mass | 139.0763918 |
| Topological Polar Surface Area | 20.2 |
| Heavy Atom Count | 8 |
| Melting Point | 305 °C (decomposes) |
|---|---|
| Melting Point | 305 °C |
| LogP | -5.16 |
| pH | 4.7 (10% SOLN IN WATER) |
CHOLINE CHLORIDE; 67-48-1; Lipotril; Hepacholine; Paresan; 2-Hydroxy-N,N,N-trimethylethanaminium chloride; (2-Hydroxyethyl)trimethylammonium chloride; Hormocline; Biocolina; Luridin chloride; Choline hydrochloride; Neocolina; Bilineurin chloride; Biocoline; Cholinium chloride; Choline, chloride
| 法规与食品接触 | FDA Substance added to food: NUTRIENT SUPPLEMENT FLAVOURING_AGENT: Flavouring Agent Flavoring Agents Savory, Umami No safety concern at current levels of intake when used as a flavouring agent TRS 960-JECFA 73/49 |
|---|---|
| GHS 通报统计 | 53.5% (236 / 441) |
| GHS 通报统计 | 53.5% (236 / 441) |
|---|---|
| 已通报的危害声明 | H315 (46%), H319 (46%), H335 (45.6%) |
氯化胆碱 的 CAS 号为 67-48-1，分子式 C5H14ClNO，分子量 139.08 g/mol。 UNII 45I14D8O27; ChEBI 133341; InChIKey SGMZJAMFUVOLNK-UHFFFAOYSA-M. Melting Point: 305 °C (decomposes); Melting Point: 305 °C; LogP: -5.16.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Choline chloride