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chlorphenamine

CAS 132-22-9C16H19ClN2MW 274.79

chlorphenamine (CAS 132-22-9) — formula C16H19ClN2, molecular weight 274.79; category organic chemicals.

Product Overview

CAS Number132-22-9
Molecular FormulaC16H19ClN2
Molecular Weight274.79
Melting Point130 - 135 °C
Boiling Point142
LogP3.38
ApplicationsUses: MEDICATION, MEDICATION (VET):, Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 788, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Consumption (g per capita) in the USA (2002): 0.00279, Calculated removal (%): 21.7, Used used in the prevention of the symptoms of allergic conditions such as rhinitis, urticaria, allergy, common cold, asthma and hay fever., Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: CONDENSATION OF 2-(P-CHLORO-ALPHA-(2-CHLOROETHYL)BENZYL)PYRIDINE WITH DIMETHYLAMINE IN THE PRESENCE OF SODAMIDE, Synthesis., Formulations, Preparations: TABLETS, 4 MG, REPEAT-ACTION TABLETS, 8 & 12 MG, INJECTION, SYRUP, FROM TABLE, GRADE: USP, MALEATE, U.S. Production: (1977) 1.68X10+7 GRAMS (MALEATE), (1978) 2.13X10+7 GRAMS (MALEATE), U.S. Imports: (1977) 5.0X10+6 G-INCL MALEATE (PRINCPL DISTS), (1979) 2.0X10+7 G-INCL MALEATE (PRINCPL DISTS), General Manufacturing Information: 2-Pyridinepropanamine, .gamma.-(4-chlorophenyl)-N, N-dimethyl-: INACTIVE, TREATMENT OF BASE WITH EQUIMOLAR PORTION OF MALEIC ACID RESULTS IN FORMATION OF MALEATE.
CategoryOrganic Chemicals

Applications

Documented applications: Uses: MEDICATION, MEDICATION (VET):, Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 788, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Consumption (g per capita) in the USA (2002): 0.00279, Calculated removal (%): 21.7, Used used in the prevention of the symptoms of allergic conditions such as rhinitis, urticaria, allergy, common cold, asthma and hay fever., Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: CONDENSATION OF 2-(P-CHLORO-ALPHA-(2-CHLOROETHYL)BENZYL)PYRIDINE WITH DIMETHYLAMINE IN THE PRESENCE OF SODAMIDE, Synthesis., Formulations, Preparations: TABLETS, 4 MG, REPEAT-ACTION TABLETS, 8 & 12 MG, INJECTION, SYRUP, FROM TABLE, GRADE: USP, MALEATE, U.S. Production: (1977) 1.68X10+7 GRAMS (MALEATE), (1978) 2.13X10+7 GRAMS (MALEATE), U.S. Imports: (1977) 5.0X10+6 G-INCL MALEATE (PRINCPL DISTS), (1979) 2.0X10+7 G-INCL MALEATE (PRINCPL DISTS), General Manufacturing Information: 2-Pyridinepropanamine, .gamma.-(4-chlorophenyl)-N, N-dimethyl-: INACTIVE, TREATMENT OF BASE WITH EQUIMOLAR PORTION OF MALEIC ACID RESULTS IN FORMATION OF MALEATE..

Technical Profile

What this product is

chlorphenamine is a carbon-based organic compound with CAS registry number 132-22-9 and molecular formula C16H19ClN2 (molecular weight 274.79), belonging to the organic chemicals segment of chemical raw materials.

Identification

CAS number: 132-22-9

Its molecular formula C16H19ClN2 comprises 16 C, 19 H, 1 Cl, 2 N atoms.

Also known as: chlorphenamine · 扑尔敏

Category: organic chemicals

Frequently Asked Questions

What is the CAS number of chlorphenamine?

The CAS registry number of chlorphenamine is 132-22-9.

What is the molecular formula and molecular weight of chlorphenamine?

Molecular formula C16H19ClN2, molecular weight 274.79.

What other names is chlorphenamine known by?

It is also registered under: chlorphenamine, 扑尔敏.

What are the documented applications of chlorphenamine?

Recorded applications: Uses: MEDICATION, MEDICATION (VET):, Use (kg, approx.) in Germany (2009): >250, Use (kg) in USA (2002): 788, Consumption (g per capita, approx.) in Germany (2009): 0.00305, Consumption (g per capita) in the USA (2002): 0.00279, Calculated removal (%): 21.7, Used used in the prevention of the symptoms of allergic conditions such as rhinitis, urticaria, allergy, common cold, asthma and hay fever., Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan, Methods of Manufacturing: CONDENSATION OF 2-(P-CHLORO-ALPHA-(2-CHLOROETHYL)BENZYL)PYRIDINE WITH DIMETHYLAMINE IN THE PRESENCE OF SODAMIDE, Synthesis., Formulations, Preparations: TABLETS, 4 MG, REPEAT-ACTION TABLETS, 8 & 12 MG, INJECTION, SYRUP, FROM TABLE, GRADE: USP, MALEATE, U.S. Production: (1977) 1.68X10+7 GRAMS (MALEATE), (1978) 2.13X10+7 GRAMS (MALEATE), U.S. Imports: (1977) 5.0X10+6 G-INCL MALEATE (PRINCPL DISTS), (1979) 2.0X10+7 G-INCL MALEATE (PRINCPL DISTS), General Manufacturing Information: 2-Pyridinepropanamine, .gamma.-(4-chlorophenyl)-N, N-dimethyl-: INACTIVE, TREATMENT OF BASE WITH EQUIMOLAR PORTION OF MALEIC ACID RESULTS IN FORMATION OF MALEATE..

Which category does chlorphenamine belong to?

Category: Organic Chemicals.

PubChem Public Data

Independent reference data for chlorphenamine (CAS 132-22-9), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number132-22-9
PubChem CID2725
Molecular formulaC16H19ClN2
IUPAC name3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
UNII (FDA)3U6IO1965U

Computed descriptors

Molecular Weight274.79
XLogP33.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass274.1236763
Monoisotopic Mass274.1236763
Topological Polar Surface Area16.1
Heavy Atom Count19

Physicochemical values on record

Boiling Point142
Boiling Point142 °C @ 1.0 MM HG
Melting Point130 - 135 °C
Solubility5500
Solubility160.0 mg/mL at 25 °C
LogP3.38
LogP3.66
Dissociation Constants9.26
Dissociation Constants9.13 (at 25 °C)

Documented uses on record

    Use (kg; approx.) in Germany (2009): >250Consumption (g per capita; approx.) in Germany (2009): 0.00305

    Synonyms and trade names

    chlorpheniramine; Chlorphenamine; 132-22-9; Chlorophenylpyridamine; Haynon; Clorfeniramina; Allergican; Allergisan; Clorfenamina; Histadur; Chloropheniramine; Chlorprophenpyridamine; Chloroprophenpyridamine; Chlorpheniraminum; Chlorphenaminum; 4-Chloropheniramine

    What the public record says

    chlorphenamine · CAS 132-22-9 · C16H19ClN2. UNII 3U6IO1965U. Boiling Point: 142; Boiling Point: 142 °C @ 1.0 MM HG; Melting Point: 130 - 135 °C.

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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