氯喹（CAS 54-05-7）：分子式 C18H26ClN3、分子量 319.9。
| CAS号 | 54-05-7 |
|---|---|
| 分子式 | C18H26ClN3 |
| 分子量 | 319.9 |
| 熔点 | 87-89.5 |
| LogP | 4.63 |
| 应用领域 | Uses: MEDICATION、Antimalarial、antiamebic、antitheuratic、Lupus erthematus supressant、Mesh Heading: Amebicides、antimalarials、antirheumatic Agents、Use (kg、approx.) in Germany (2009): >750、Consumption (g per capita、approx.) in Germany (2009): 0.00916、Excretion rate: 0.7、Calculated removal (%): 78.6、For the suppressive treatment and for acute attacks of malaria due to P. vivax、P.malariae、P. ovale、and susceptible strains of P. falciparum、Second-line agent in treatment of Rheumatoid Arthritis (A308).、Use Classification: Pharmaceuticals、Methods of Manufacturing: H. Andersag et al.、US 2233970 (1941 to Winthrop)、Condensation of 4、7-dichloroquinoline with 1-diethylamino-4-aminopentane: German patent 683692 (1939)、Formulations、Preparations: Chloroquine phosphate、USP ... is available as tablets containing either 250 or 500 mg of diphosphate. Approximately 60% of diphosphate represents base.、Chloroquine phosphate、Arechin、Avloclor、Imagon、Malaquin、Resochin、Tresochin.、Chloroquine diphosphate、Nivaquine.、Chloroquine Sulfate、Tablets (as the phosphate)、500 mg. Vials (as the dihydrochloride)、50 mg、ml.、Chloroquine Phosphate: Oral tablets 300 mg or 150 mg (of chloroquine).、U.S. Production: (1977) PROBABLY MORE THAN 4.5X10+5 G、PHOSPHATE、(1979) PROBABLY MORE THAN 4.5X10+5 G、U.S. Imports: (1977) 6X10+5 G-PRINCPL CUSTMS DISTS、(1979) 3X10+5 G-PRINCPL CUSTMS DISTS、General Manufacturing Information: Usually dispensed as the phosphate. |
登记用途：Uses: MEDICATION、Antimalarial、antiamebic、antitheuratic、Lupus erthematus supressant、Mesh Heading: Amebicides、antimalarials、antirheumatic Agents、Use (kg、approx.) in Germany (2009): >750、Consumption (g per capita、approx.) in Germany (2009): 0.00916、Excretion rate: 0.7、Calculated removal (%): 78.6、For the suppressive treatment and for acute attacks of malaria due to P. vivax、P.malariae、P. ovale、and susceptible strains of P. falciparum、Second-line agent in treatment of Rheumatoid Arthritis (A308).、Use Classification: Pharmaceuticals、Methods of Manufacturing: H. Andersag et al.、US 2233970 (1941 to Winthrop)、Condensation of 4、7-dichloroquinoline with 1-diethylamino-4-aminopentane: German patent 683692 (1939)、Formulations、Preparations: Chloroquine phosphate、USP ... is available as tablets containing either 250 or 500 mg of diphosphate. Approximately 60% of diphosphate represents base.、Chloroquine phosphate、Arechin、Avloclor、Imagon、Malaquin、Resochin、Tresochin.、Chloroquine diphosphate、Nivaquine.、Chloroquine Sulfate、Tablets (as the phosphate)、500 mg. Vials (as the dihydrochloride)、50 mg、ml.、Chloroquine Phosphate: Oral tablets 300 mg or 150 mg (of chloroquine).、U.S. Production: (1977) PROBABLY MORE THAN 4.5X10+5 G、PHOSPHATE、(1979) PROBABLY MORE THAN 4.5X10+5 G、U.S. Imports: (1977) 6X10+5 G-PRINCPL CUSTMS DISTS、(1979) 3X10+5 G-PRINCPL CUSTMS DISTS、General Manufacturing Information: Usually dispensed as the phosphate.。
氯喹 是一种化工化合物，登记 CAS 号为 54-05-7，分子式 C18H26ClN3（分子量 319.9）。
登记 CAS 号：54-05-7
其分子式 C18H26ClN3 由 18 个碳、26 个氢、1 个氯、3 个氮 组成。
别名/同义词：氯喹 · chloroquine
氯喹 的 CAS 登记号为 54-05-7。
分子式 C18H26ClN3，分子量 319.9。
别名/同义词：氯喹、chloroquine。
登记用途：Uses: MEDICATION、Antimalarial、antiamebic、antitheuratic、Lupus erthematus supressant、Mesh Heading: Amebicides、antimalarials、antirheumatic Agents、Use (kg、approx.) in Germany (2009): >750、Consumption (g per capita、approx.) in Germany (2009): 0.00916、Excretion rate: 0.7、Calculated removal (%): 78.6、For the suppressive treatment and for acute attacks of malaria due to P. vivax、P.malariae、P. ovale、and susceptible strains of P. falciparum、Second-line agent in treatment of Rheumatoid Arthritis (A308).、Use Classification: Pharmaceuticals、Methods of Manufacturing: H. Andersag et al.、US 2233970 (1941 to Winthrop)、Condensation of 4、7-dichloroquinoline with 1-diethylamino-4-aminopentane: German patent 683692 (1939)、Formulations、Preparations: Chloroquine phosphate、USP ... is available as tablets containing either 250 or 500 mg of diphosphate. Approximately 60% of diphosphate represents base.、Chloroquine phosphate、Arechin、Avloclor、Imagon、Malaquin、Resochin、Tresochin.、Chloroquine diphosphate、Nivaquine.、Chloroquine Sulfate、Tablets (as the phosphate)、500 mg. Vials (as the dihydrochloride)、50 mg、ml.、Chloroquine Phosphate: Oral tablets 300 mg or 150 mg (of chloroquine).、U.S. Production: (1977) PROBABLY MORE THAN 4.5X10+5 G、PHOSPHATE、(1979) PROBABLY MORE THAN 4.5X10+5 G、U.S. Imports: (1977) 6X10+5 G-PRINCPL CUSTMS DISTS、(1979) 3X10+5 G-PRINCPL CUSTMS DISTS、General Manufacturing Information: Usually dispensed as the phosphate.。
氯喹（CAS 54-05-7）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 54-05-7 |
|---|---|
| PubChem CID | 2719 |
| Molecular formula | C18H26ClN3 |
| IUPAC name | 4-N-(7-chloroquinolin-4-yl)-1-N,1-N-diethylpentane-1,4-diamine |
| UNII (FDA) | 886U3H6UFF |
| Molecular Weight | 319.9 |
|---|---|
| XLogP3 | 4.6 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 8 |
| Exact Mass | 319.1815255 |
| Monoisotopic Mass | 319.1815255 |
| Topological Polar Surface Area | 28.2 |
| Heavy Atom Count | 22 |
| Melting Point | 87-89.5 |
|---|---|
| Melting Point | 87 °C |
| Melting Point | 289 °C |
| Solubility | 1.75e-02 g/L |
| LogP | 4.63 |
| LogP | log Kow = 4.63 |
| LogP | 4.3 |
| LogP | 4.61 |
| Dissociation Constants | 10.1 |
| Dissociation Constants | pKa = 10.1 |
chloroquine; 54-05-7; Aralen; Chloraquine; Chlorochin; Artrichin; Chloroquina; Reumachlor; Chloroquinium; Capquin; Chlorquin; Arthrochin; Bipiquin; Clorochina; Gontochin; Klorokin
| Reported hazard statements | H302 (100%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
chloroquine · CAS 54-05-7 · C18H26ClN3. UNII 886U3H6UFF. Melting Point: 87-89.5; Melting Point: 87 °C; Melting Point: 289 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: chloroquine