(+-)-头孢噻吩（CAS 51098-29-4）：分子式 C16H16N2O6S2、分子量 396.4。
| CAS号 | 51098-29-4 |
|---|---|
| 分子式 | C16H16N2O6S2 |
| 分子量 | 396.4 |
| 熔点 | 160-160.5 °C |
| LogP | -0.2 |
| 应用领域 | Uses: Vet: Antibacterial ... usually quite active against many gram-positive bacteria ... moderately active against gram-negative bacteria ... relatively susceptible to beta-lactamases ... not as effetive against anaerobes as ... penicillins.、First-generation cephalosporins、Mesh Heading: anti-bacterial agents、MEDICATION、MEDICATION (VET)、Use Classification: Pharmaceuticals、Methods of Manufacturing: ... E. H. Flynn、US patent 3、218、318 (1965 to Lilly)、French patent 1、384、197 (1965 to Glaxo).、REACTION OF 7-AMINOCEPHALOSPORANIC ACID WITH THIOPHENE ACETYL CHLORIDE IN ACETONE、7-AMINOCEPHALOSPORANIC ACID IS N-ACETYLATED...WITH 2-THIOPHENEACETYL CHLORIDE IN...DEHYDROCHLORINATING ENVIRONMENT. STARTING ACID...PREPD FROM NATURAL ANTIBIOTIC、CEPHALOSPORIN C、BY EITHER PROTON-CATALYZED OR ENZYMATIC HYDROLYSIS. CEPHALOTHIN...CONVERTED TO SODIUM SALT BY INTERACTION WITH SODIUM ACETATE...、SODIUM、Formulations、Preparations: Sterile cephalothin sodium、USP (keflin)、is marketed in 10-mL rubber-stoppered vials containing either 1、2、or 4 g.、Consumption Patterns: ESSENTIALLY 100% AS AN ANTIBIOTIC (AS SODIUM SALT)、U.S. Production: (1977) PROBABLY GREATER THAN 4.54X10+5 GRAMS、(1979) PROBABLY GREATER THAN 4.5X10+5 G-SODIUM、General Manufacturing Information: Cephalothin is semisynthetic derivative of cephalosporin C ...、CEPHALOSPORINS ARE INCOMPATIBLE WITH ERYTHROMYCIN & TETRACYCLINES IN PARENTERAL MIXTURES.、CEPHALOSPORINS、FROM TABLE、Cephalosporin C is very resistant to action of penicillinase、for which it is both competitive and noncompetitive inhibitor、depending on substrate tested ...、Cephalosporins |
登记用途：Uses: Vet: Antibacterial ... usually quite active against many gram-positive bacteria ... moderately active against gram-negative bacteria ... relatively susceptible to beta-lactamases ... not as effetive against anaerobes as ... penicillins.、First-generation cephalosporins、Mesh Heading: anti-bacterial agents、MEDICATION、MEDICATION (VET)、Use Classification: Pharmaceuticals、Methods of Manufacturing: ... E. H. Flynn、US patent 3、218、318 (1965 to Lilly)、French patent 1、384、197 (1965 to Glaxo).、REACTION OF 7-AMINOCEPHALOSPORANIC ACID WITH THIOPHENE ACETYL CHLORIDE IN ACETONE、7-AMINOCEPHALOSPORANIC ACID IS N-ACETYLATED...WITH 2-THIOPHENEACETYL CHLORIDE IN...DEHYDROCHLORINATING ENVIRONMENT. STARTING ACID...PREPD FROM NATURAL ANTIBIOTIC、CEPHALOSPORIN C、BY EITHER PROTON-CATALYZED OR ENZYMATIC HYDROLYSIS. CEPHALOTHIN...CONVERTED TO SODIUM SALT BY INTERACTION WITH SODIUM ACETATE...、SODIUM、Formulations、Preparations: Sterile cephalothin sodium、USP (keflin)、is marketed in 10-mL rubber-stoppered vials containing either 1、2、or 4 g.、Consumption Patterns: ESSENTIALLY 100% AS AN ANTIBIOTIC (AS SODIUM SALT)、U.S. Production: (1977) PROBABLY GREATER THAN 4.54X10+5 GRAMS、(1979) PROBABLY GREATER THAN 4.5X10+5 G-SODIUM、General Manufacturing Information: Cephalothin is semisynthetic derivative of cephalosporin C ...、CEPHALOSPORINS ARE INCOMPATIBLE WITH ERYTHROMYCIN & TETRACYCLINES IN PARENTERAL MIXTURES.、CEPHALOSPORINS、FROM TABLE、Cephalosporin C is very resistant to action of penicillinase、for which it is both competitive and noncompetitive inhibitor、depending on substrate tested ...、Cephalosporins。
(+-)-头孢噻吩 是一种化工化合物，登记 CAS 号为 51098-29-4，分子式 C16H16N2O6S2（分子量 396.4）。
登记 CAS 号：51098-29-4
其分子式 C16H16N2O6S2 由 16 个碳、16 个氢、2 个氮、6 个氧、2 个硫 组成。
别名/同义词：(+-)-头孢噻吩 · (+-)-Cephalothin
(+-)-头孢噻吩 的 CAS 登记号为 51098-29-4。
分子式 C16H16N2O6S2，分子量 396.4。
别名/同义词：(+-)-头孢噻吩、(+-)-Cephalothin。
登记用途：Uses: Vet: Antibacterial ... usually quite active against many gram-positive bacteria ... moderately active against gram-negative bacteria ... relatively susceptible to beta-lactamases ... not as effetive against anaerobes as ... penicillins.、First-generation cephalosporins、Mesh Heading: anti-bacterial agents、MEDICATION、MEDICATION (VET)、Use Classification: Pharmaceuticals、Methods of Manufacturing: ... E. H. Flynn、US patent 3、218、318 (1965 to Lilly)、French patent 1、384、197 (1965 to Glaxo).、REACTION OF 7-AMINOCEPHALOSPORANIC ACID WITH THIOPHENE ACETYL CHLORIDE IN ACETONE、7-AMINOCEPHALOSPORANIC ACID IS N-ACETYLATED...WITH 2-THIOPHENEACETYL CHLORIDE IN...DEHYDROCHLORINATING ENVIRONMENT. STARTING ACID...PREPD FROM NATURAL ANTIBIOTIC、CEPHALOSPORIN C、BY EITHER PROTON-CATALYZED OR ENZYMATIC HYDROLYSIS. CEPHALOTHIN...CONVERTED TO SODIUM SALT BY INTERACTION WITH SODIUM ACETATE...、SODIUM、Formulations、Preparations: Sterile cephalothin sodium、USP (keflin)、is marketed in 10-mL rubber-stoppered vials containing either 1、2、or 4 g.、Consumption Patterns: ESSENTIALLY 100% AS AN ANTIBIOTIC (AS SODIUM SALT)、U.S. Production: (1977) PROBABLY GREATER THAN 4.54X10+5 GRAMS、(1979) PROBABLY GREATER THAN 4.5X10+5 G-SODIUM、General Manufacturing Information: Cephalothin is semisynthetic derivative of cephalosporin C ...、CEPHALOSPORINS ARE INCOMPATIBLE WITH ERYTHROMYCIN & TETRACYCLINES IN PARENTERAL MIXTURES.、CEPHALOSPORINS、FROM TABLE、Cephalosporin C is very resistant to action of penicillinase、for which it is both competitive and noncompetitive inhibitor、depending on substrate tested ...、Cephalosporins。
(+-)-头孢噻吩（CAS 51098-29-4）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 51098-29-4 |
|---|---|
| PubChem CID | 6024 |
| 分子式 | C16H16N2O6S2 |
| IUPAC 名称 | (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-thiophen-2-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| UNII（FDA） | R72LW146E6 |
| Molecular Weight | 396.4 |
|---|---|
| XLogP3 | -0.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 7 |
| Exact Mass | 396.04497858 |
| Monoisotopic Mass | 396.04497858 |
| Topological Polar Surface Area | 167 |
| Heavy Atom Count | 26 |
| Melting Point | 160-160.5 °C |
|---|---|
| Melting Point | 160 - 160.5 °C |
| Solubility | 158 |
| Solubility | 5.21e-02 g/L |
| LogP | -0.2 |
cephalothin; Cefalotin; 153-61-7; Cephalotin; Cefalothin; Cephalothinum; Cefalotina; Cemastin; Cefalotine; Coaxin; Averon-1; Cefalotinum; 7-(2-Thienylacetamido)cephalosporanic acid; 7-(Thiophene-2-acetamido)cephalosporin; 7-(Thiophene-2-acetamido)cephalosporanic acid; DTXSID4022783
| 已通报的危害声明 | H317 (100%), H334 (100%) |
|---|
(+-)-头孢噻吩 · CAS 51098-29-4 · C16H16N2O6S2. UNII R72LW146E6. Melting Point: 160-160.5 °C; Melting Point: 160 - 160.5 °C; Solubility: 158.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: (+-)-Cephalothin