Cenobamate

Independent reference data for Cenobamate (CAS 913088-80-9), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Cenobamate is indicated for the treatment of partial onset seizures in adults.Cenobamate is a tetrazole carbamate anticonvulsant used as therapy of partial onset seizures in adults. Cenobamate is associated with a low-to-moderate rate of serum aminotransferase elevations during therapy and has been linked to cases of clinically apparent liver injury usually in the context of a multiorgan hypersensitivity syndrome such as drug reaction with eosinophilia and systemic symptoms (DRESS).

Synonyms and trade names

Cenobamate; 913088-80-9; Xcopri; YKP-3089; YKP3089; Cenobamato; P85X70RZWS; [(1R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl] Carbamate; Carbamic acid (R)-(+)-1-(2-chlorophenyl)-2-(2H-tetrazol-2-yl)ethyl ester; DTXSID001027948; 2H-Tetrazole-2-ethanol, alpha-(2-chlorophenyl)-, carbamate (ester), (alphaR)-; (1R)-1-(2-chlorophenyl)-2-(2H-1,2,3,4-tetrazol-2-yl)ethyl carbamate; 2H-Tetrazole-2-ethanol, alpha-(2-chlorophenyl)-, 2-carbamate, (alphaR)-; Cenobamatum; ((1R)-1-(2-chlorophenyl)-2-(tetrazol-2-yl)ethyl) carbamate; Xcopri Titration Pack

GHS hazard classification

Reported hazard statements	H371 (100%), H373 (100%)

H361d (100%): Suspected of damaging the unborn child [Warning Reproductive toxicity]

H371 (100%): May cause damage to organs [Warning Specific target organ toxicity, single exposure]

What the public record says

Cenobamate · CAS 913088-80-9 · C10H10ClN5O2. UNII P85X70RZWS. Solubility: 1.7mg/mL; LogP: 0.456.

Source: PubChem / Wikidata; the batch COA governs where values differ.