carbinoxamine

Description

carbinoxamine · CAS 486-16-8 · C16H19ClN2O. UNII 982A7M02H5. Boiling Point: 160; Melting Point: < 25 °C; Solubility: 2.28e-01 g/L.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Solid
• 169.28 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 157.64 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 166.33 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 165.78 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Documented Uses

• For symptomatic relief of seasonal and perennial allergic rhinitis and vasomotor rhinitis, as well as allergic conjunctivitis caused by foods and inhaled allergens. Also for the relief of allergic reactions to blood or plasma, and the symptomatic management of mild, uncomplicated allergic skin manifestations of urticaria and angioedema.
• Carbinoxamine is a first generation antihistamine that is used for symptoms of allergic rhinitis and the common cold. Carbinoxamine has not been linked to instances of clinically apparent acute liver injury.
• Breast Feeding; Lactation; Milk, Human; Antihistamines
• Avoid alcohol. Ingesting alcohol may increase drowsiness caused by carbinoxamine.
• Mechanisms of Action [MoA] - Histamine H1 Receptor Antagonists
• Established Pharmacologic Class [EPC] - Histamine-1 Receptor Antagonist

Synonyms

carbinoxamine; 486-16-8; Paracarbinoxamine; Allergefon; Carbinoxamina; Carbinoxaminum; (+-)-Carbinoxamine; Carbinoxamine base; Palgic; 2-(p-Chloro-alpha-(2-(dimethylamino)ethoxy)benzyl)pyridine; 982A7M02H5; Ethanamine, 2-((4-chlorophenyl)-2-pyridinylmethoxy)-N,N-dimethyl-; Ethanamine, 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethyl-; CHEBI:3398; DTXSID4022737; N,N-Dimethyl-2-(p-chloro-alpha-(2-pyridyl)benzyloxy)ethylamine

Frequently Asked Questions

What are the CAS number and molecular formula of carbinoxamine?

CAS 486-16-8; molecular formula C16H19ClN2O; molecular weight — g/mol.

What other names is carbinoxamine known by?

carbinoxamine, 486-16-8, Paracarbinoxamine, Allergefon, Carbinoxamina, Carbinoxaminum.

What are the key physical properties of carbinoxamine?

Boiling Point: 160; Melting Point: < 25 °C; Solubility: 2.28e-01 g/L; LogP: 2.6.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.