bretylium tosylate

Independent reference data for bretylium tosylate (CAS 61-75-6), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Documented uses on record

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Synonyms and trade names

Bretylium tosylate; 61-75-6; Bretylol; Bretylium tosilate; Darentin; Tosilato de bretilio; Tosilate de bretylium; Bretylii tosilas; ASL-603; (o-Bromobenzyl)ethyldimethylammonium p-toluenesulfonate; Bretilio tosilato; DTXSID1022685; Bretylium Tosylate In Dextrose 5%; NSC-62164; 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-methylbenzenesulfonate; Dimethylethyl-o-bromobenzylammonium-p-toluenesulphonate

GHS hazard classification

Reported hazard statements	H302 (100%), H312 (97.6%), H332 (97.6%)

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]

H312 (97.6%): Harmful in contact with skin [Warning Acute toxicity, dermal]

What the public record says

bretylium tosylate · CAS 61-75-6 · C18H24BrNO3S. UNII 78ZP3YR353.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.