Azaperone

Description

Azaperone · CAS 1649-18-9 · C19H22FN3O. UNII 19BV78AK7W. LogP: 3.3; Collision Cross Section: 181.99 Ų [M+H]+.

Identification

CAS Registry Number	1649-18-9
PubChem CID	15443
Molecular formula	C19H22FN3O
IUPAC name	1-(4-fluorophenyl)-4-(4-pyridin-2-ylpiperazin-1-yl)butan-1-one
UNII (FDA)	19BV78AK7W

Computed Descriptors

Molecular Weight	327.4
XLogP3	3.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	327.17469050
Monoisotopic Mass	327.17469050
Topological Polar Surface Area	36.4
Heavy Atom Count	24
Formal Charge	0

Physical & Chemical Properties

LogP	3.3
Collision Cross Section	181.99 Ų [M+H]+

Physical description & handling notes

• 178.92 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 169.98 Ų [M+K]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 165.58 Ų [M+H-H2O]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 177.25 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
• 180.3 Ų [M+H]+ [CCS Type: TW]
• 180 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Regulatory Status

Regulatory & Food Contact	TRANQUILLIZING_AGENT: Veterinary Drug JECFA ADI: 0-0.006 mg/kg bw (1999) TRS 893-JECFA 52/85 FAS 41-JECFA 50/149 (1998)

GHS Hazard Classification

Reported hazard statements	H301 (100%)

Documented Uses

• Used to sedate pigs for transport; [Kanerva, p. 1753]
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
• Veterinary Drug -> TRANQUILLIZING_AGENT -> JECFA Functional Classes
• Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
• Azaperone (Class: Depressants and Tranquilizers, Added Date: 06-2018)
• Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.

Synonyms

Azaperone; 1649-18-9; Fluoperidol; Stresnil; Suicalm; Azaperon; Azaperona; R-1929; Azaperonum; 1-Butanone, 1-(4-fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-; NSC 170976; DTXSID2045361; R 1929; 1-(3-(4-Fluorobenzoyl)propyl)-4-(2-pyridyl)piperazine; 1-(4-Fluorophenyl)-4-[4-(2-pyridinyl)-1-piperazinyl]-1-butanone; 4'-Fluoro-4-(4-(2-pyridyl)-1-piperazinyl)butyrophenone

Frequently Asked Questions

What are the CAS number and molecular formula of Azaperone?

CAS 1649-18-9; molecular formula C19H22FN3O; molecular weight — g/mol.

What other names is Azaperone known by?

Azaperone, 1649-18-9, Fluoperidol, Stresnil, Suicalm, Azaperon.

What is the regulatory status of Azaperone?

Documented regulatory listings: TRANQUILLIZING_AGENT: Veterinary Drug; JECFA ADI: 0-0.006 mg/kg bw (1999); TRS 893-JECFA 52/85.

Is Azaperone classified as hazardous?

Hazard statements reported: H301.

What are the key physical properties of Azaperone?

LogP: 3.3; Collision Cross Section: 181.99 Ų [M+H]+.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.