allylestrenol

Description

allylestrenol · CAS 432-60-0 · C21H32O. UNII I47VB5DZ8O. Melting Point: 80; Melting Point: 80 °C; Solubility: 5.58e-04 g/L.

Identification

CAS Registry Number	432-60-0
PubChem CID	235905
Molecular formula	C21H32O
IUPAC name	(8R,9S,10R,13S,14S,17R)-13-methyl-17-prop-2-enyl-2,3,6,7,8,9,10,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
UNII (FDA)	I47VB5DZ8O

Computed Descriptors

Molecular Weight	300.5
XLogP3	5.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	2
Exact Mass	300.245315640
Monoisotopic Mass	300.245315640
Topological Polar Surface Area	20.2
Heavy Atom Count	22
Formal Charge	0

Physical & Chemical Properties

Melting Point	80
Melting Point	80 °C
Solubility	5.58e-04 g/L

Physical description & handling notes

• Solid
• Allylestrenol is a progestogen structurally related to progesterone that has been given in threatened and recurrent miscarriage, and to prevent premature labour. However, with the exception of proven progesterone deficiency, such use is no longer recommended. In threatened miscarriage in progesterone-deficient women a suggested dose is 5 mg three times daily by mouth for 5 to 7 days.

GHS Hazard Classification

Reported hazard statements	H302 (95%), H312 (90%), H332 (95%), H351 (90%), H361 (95%)

Documented Uses

• Allylestrenol was designed to be used for miscarriage prevention, prevention of premature labour and has been investigated for possible use in men for treatment for benign prostatic hyperplasia.
• Compounds that interact with PROGESTERONE RECEPTORS in target tissues to bring about the effects similar to those of PROGESTERONE. Primary actions of progestins, including natural and synthetic steroids, are on the UTERUS and the MAMMARY GLAND in preparation for and in maintenance of PREGNANCY.
• G - Genito urinary system and sex hormones
• G03 - Sex hormones and modulators of the genital system
• QG - Genito urinary system and sex hormones
• QG03 - Sex hormones and modulators of the genital system

Synonyms

allylestrenol; 432-60-0; Gestanin; Allyloestrenol; Orageston; Perselin; Organon; Alilestrenol; 17alpha-Allylestr-4-en-17beta-ol; DTXSID9022574; Allilestrenolo; Allylestrenolum; I47VB5DZ8O; NSC-37723; 17-(2-Propenyl)estr-4-en-17-ol; 17-Hydroxy-17-alpha-allyl-4-estrene

Frequently Asked Questions

What are the CAS number and molecular formula of allylestrenol?

CAS 432-60-0; molecular formula C21H32O; molecular weight — g/mol.

What other names is allylestrenol known by?

allylestrenol, 432-60-0, Gestanin, Allyloestrenol, Orageston, Perselin.

Is allylestrenol classified as hazardous?

Hazard statements reported: H302, H312, H332, H351, H361.

What are the key physical properties of allylestrenol?

Melting Point: 80; Melting Point: 80 °C; Solubility: 5.58e-04 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.