9H-嘌呤-6-胺，9-b-D-阿拉伯呋喃糖基-，水合物(1:1)（CAS 24356-66-9）：分子式 C10H13N5O4、分子量 267.24。
| CAS号 | 24356-66-9 |
|---|---|
| 分子式 | C10H13N5O4 |
| 分子量 | 267.24 |
| 熔点 | 500 to 518 °F (NTP, 1992) |
| LogP | -2.115 |
| 应用领域 | Uses: MEDICATION、THERAP CAT: ANTIVIRAL、A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses、the VACCINIA VIRUS and varicella zoster virus、VIRA-A Vidarabine、3% ointment、ophthalmic: Discontinued、VIRA-A (vidarabine) eq 187.4 mg base、ml、injectable、injection: Discontinued、Used as an initial treatment for the termination of paroxysmal supraventricular tachycardia (PVST)、including that associated with accessory bypass tracts、and is a drug of choice for terminating stable、narrow-complex supraventricular tachycardias (SVT). Also used as an adjunct to thallous chloride TI 201 myocardial perfusion scintigraphy (thallium stress test) in patients who are unable to exercise adequately、as well as an adjunct to vagal maneuvers and clinical assessment to establish a specific diagnosis of undefined、stable、narrow-complex SVT.、Methods of Manufacturing: Originally prepared by chemical synthesis at Stanford Research Institute、and later isolated from a fermentation beer of Streptomyces antibioticus.、Formulations、Preparations: Ophthalmic Ointment 3% (equivalent to vidarabine、Vira-A、Parke-Davis anhydrous 2.8%)、Parenteral: Concentrate、for injection、for iv infusion、200 mg、ml (equivalent to 187.4 mg of anhydrous vidarabine per ml). Vira-A (with benzethonium chloride and phosphate buffers)、Parke-Davis、Vidarabine、not currently approved for use in the United States、General Manufacturing Information: 9H-Purin-6-amine、9-.beta.-D-arabinofuranosyl-: INACTIVE |
登记用途：Uses: MEDICATION、THERAP CAT: ANTIVIRAL、A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses、the VACCINIA VIRUS and varicella zoster virus、VIRA-A Vidarabine、3% ointment、ophthalmic: Discontinued、VIRA-A (vidarabine) eq 187.4 mg base、ml、injectable、injection: Discontinued、Used as an initial treatment for the termination of paroxysmal supraventricular tachycardia (PVST)、including that associated with accessory bypass tracts、and is a drug of choice for terminating stable、narrow-complex supraventricular tachycardias (SVT). Also used as an adjunct to thallous chloride TI 201 myocardial perfusion scintigraphy (thallium stress test) in patients who are unable to exercise adequately、as well as an adjunct to vagal maneuvers and clinical assessment to establish a specific diagnosis of undefined、stable、narrow-complex SVT.、Methods of Manufacturing: Originally prepared by chemical synthesis at Stanford Research Institute、and later isolated from a fermentation beer of Streptomyces antibioticus.、Formulations、Preparations: Ophthalmic Ointment 3% (equivalent to vidarabine、Vira-A、Parke-Davis anhydrous 2.8%)、Parenteral: Concentrate、for injection、for iv infusion、200 mg、ml (equivalent to 187.4 mg of anhydrous vidarabine per ml). Vira-A (with benzethonium chloride and phosphate buffers)、Parke-Davis、Vidarabine、not currently approved for use in the United States、General Manufacturing Information: 9H-Purin-6-amine、9-.beta.-D-arabinofuranosyl-: INACTIVE。
9H-嘌呤-6-胺，9-b-D-阿拉伯呋喃糖基-，水合物(1:1) 是一种化工化合物，登记 CAS 号为 24356-66-9，分子式 C10H13N5O4（分子量 267.24）。
登记 CAS 号：24356-66-9
其分子式 C10H13N5O4 由 10 个碳、13 个氢、5 个氮、4 个氧 组成。
别名/同义词：9H-嘌呤-6-胺，9-b-D-阿拉伯呋喃糖基-，水合物(1:1) · 9H-Purin-6-amine, 9-b-D-arabinofuranosyl-, hydrate(1:1)
9H-嘌呤-6-胺，9-b-D-阿拉伯呋喃糖基-，水合物(1:1) 的 CAS 登记号为 24356-66-9。
分子式 C10H13N5O4，分子量 267.24。
别名/同义词：9H-嘌呤-6-胺，9-b-D-阿拉伯呋喃糖基-，水合物(1:1)、9H-Purin-6-amine, 9-b-D-arabinofuranosyl-, hydrate(1:1)。
登记用途：Uses: MEDICATION、THERAP CAT: ANTIVIRAL、A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses、the VACCINIA VIRUS and varicella zoster virus、VIRA-A Vidarabine、3% ointment、ophthalmic: Discontinued、VIRA-A (vidarabine) eq 187.4 mg base、ml、injectable、injection: Discontinued、Used as an initial treatment for the termination of paroxysmal supraventricular tachycardia (PVST)、including that associated with accessory bypass tracts、and is a drug of choice for terminating stable、narrow-complex supraventricular tachycardias (SVT). Also used as an adjunct to thallous chloride TI 201 myocardial perfusion scintigraphy (thallium stress test) in patients who are unable to exercise adequately、as well as an adjunct to vagal maneuvers and clinical assessment to establish a specific diagnosis of undefined、stable、narrow-complex SVT.、Methods of Manufacturing: Originally prepared by chemical synthesis at Stanford Research Institute、and later isolated from a fermentation beer of Streptomyces antibioticus.、Formulations、Preparations: Ophthalmic Ointment 3% (equivalent to vidarabine、Vira-A、Parke-Davis anhydrous 2.8%)、Parenteral: Concentrate、for injection、for iv infusion、200 mg、ml (equivalent to 187.4 mg of anhydrous vidarabine per ml). Vira-A (with benzethonium chloride and phosphate buffers)、Parke-Davis、Vidarabine、not currently approved for use in the United States、General Manufacturing Information: 9H-Purin-6-amine、9-.beta.-D-arabinofuranosyl-: INACTIVE。
9H-嘌呤-6-胺，9-b-D-阿拉伯呋喃糖基-，水合物(1:1)（CAS 24356-66-9）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 24356-66-9 |
|---|---|
| PubChem CID | 21704 |
| Molecular formula | C10H13N5O4 |
| IUPAC name | (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
| UNII (FDA) | 3XQD2MEW34 |
| Molecular Weight | 267.24 |
|---|---|
| XLogP3 | -1.1 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 2 |
| Exact Mass | 267.09675391 |
| Monoisotopic Mass | 267.09675391 |
| Topological Polar Surface Area | 140 |
| Heavy Atom Count | 19 |
| Melting Point | 500 to 518 °F (NTP, 1992) |
|---|---|
| Melting Point | 257.0-257.5 °C (0.4 H2O) |
| Melting Point | 257.00 °C. @ 760.00 mm Hg |
| Solubility | 1.40e+01 g/L |
| LogP | -2.115 |
| LogP | log Kow = -1.11 |
Vidarabine; 5536-17-4; Adenine arabinoside; Ara-A; Arabinosyladenine; Vira-A; Spongoadenosine; Araadenosine; Arasena-A; Vidarabin; 9-beta-D-Arabinofuranosyladenine; Vidarabine anhydrous; Vidarabina; Vidarabinum; beta-D-Arabinosyladenine; NSC-404241
| Reported hazard statements | H361 (97.6%) |
|---|
H361 (97.6%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
9H-Purin-6-amine, 9-b-D-arabinofuranosyl-, hydrate(1:1) · CAS 24356-66-9 · C10H13N5O4. UNII 3XQD2MEW34. Melting Point: 500 to 518 °F (NTP, 1992); Melting Point: 257.0-257.5 °C (0.4 H2O); Melting Point: 257.00 °C. @ 760.00 mm Hg.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 9H-Purin-6-amine, 9-b-D-arabinofuranosyl-, hydrate(1:1)