8-Hydroxyquinoline

Description

8-Hydroxyquinoline · CAS 148-24-3 · C9H7NO. UNII 5UTX5635HP. Boiling Point: 513 °F at 760 mmHg (NTP, 1992); Boiling Point: 267; Boiling Point: Approx 267 °C.

Identification

CAS Registry Number	148-24-3
PubChem CID	1923
Molecular formula	C9H7NO
IUPAC name	quinolin-8-ol
UNII (FDA)	5UTX5635HP

Computed Descriptors

Molecular Weight	145.16
XLogP3	2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	0
Exact Mass	145.052763847
Monoisotopic Mass	145.052763847
Topological Polar Surface Area	33.1
Heavy Atom Count	11
Formal Charge	0

Physical & Chemical Properties

Boiling Point	513 °F at 760 mmHg (NTP, 1992)
Boiling Point	267
Boiling Point	Approx 267 °C
Boiling Point	267 °C @760 [mm Hg]
Melting Point	169 °F (NTP, 1992)
Melting Point	76
Melting Point	73-75 °C
Melting Point	76 °C
Solubility	In water, 556 mg/l @ 20 °C
Density	1.034 @ 20 °C

Physical description & handling notes

• 8-hydroxyquinoline appears as white to off-white or faintly yellow crystalline powder. Phenolic odor. (NTP, 1992)
• White solid with a phenolic odor; [Hawley] White or tan powder; [MSDSonline]
• White crystals or white crystalline powder
• Phenolic odor
• less than 1 mg/mL at 61 °F (NTP, 1992)
• Insoluble

Regulatory Status

Regulatory & Food Contact	CIR / INCI: Cosmetic ingredients (Oxyquinoline) -> CIR (Cosmetic Ingredient Review) CIR / INCI: Stabilizing
GHS notification summary	0.6% (2 / 343)

GHS Hazard Classification

GHS notification summary	0.6% (2 / 343)
Reported hazard statements	H301, H317, H318, H400, H410, H302 (50.1%), H360 (40.8%), H311

Documented Uses

• Used as an antiseptic, hydrogen peroxide stabilizer, chemical reagent, corrosion inhibitor, stabilizer in nylon, chelating agent, fungicide, and brightener of steel sheets in electroplating baths; Also used to make dyes; [HSDB]
• Steel Producing [Category: Industry]
• Electroplating [Category: Plate]
• Using Disinfectants or Biocides [Category: Clean]
• CHEMICAL INTERMEDIATE FOR THE ANTI-INFECTIVE AGENT, OXYQUINOLINE BENZOATE; FOR THE FUNGICIDE, COPPER 8-QUINOLINATE; FOR DIIODOHYDROXYQUIN; FOR FUNGICIDAL SALTS IN TEXTILE PRODUCTS; ANTISEPTIC IN NUMEROUS APPLICATIONS; STABILIZER FOR HYDROGEN PEROXIDE.
• ANALYTICAL COLORIMETRIC REAGENT & FOR PRECIPITATION & SEPARATION OF METALS; PREPN OF NUMBER OF DERIVATIVES USED IN MEDICINE & INDUSTRIAL APPLICATIONS; USED TO MAKE ITS COPPER CHELATE, COPPER 8-HYDROXYQUINOLATE FOR FUNGICIDE IN AGRICULTURAL & INDUST APPLICATIONS; USED IN MFR OF DYES.

Synonyms

8-HYDROXYQUINOLINE; quinolin-8-ol; 148-24-3; 8-quinolinol; Oxyquinoline; Oxine; Quinophenol; Oxychinolin; Phenopyridine; 8-Quinol; Bioquin; Tumex; Oxin; Oxybenzopyridine; Hydroxybenzopyridine; 8-Oxyquinoline

Frequently Asked Questions

What are the CAS number and molecular formula of 8-Hydroxyquinoline?

CAS 148-24-3; molecular formula C9H7NO; molecular weight — g/mol.

What other names is 8-Hydroxyquinoline known by?

8-HYDROXYQUINOLINE, quinolin-8-ol, 148-24-3, 8-quinolinol, Oxyquinoline, Oxine.

What is the regulatory status of 8-Hydroxyquinoline?

Documented regulatory listings: CIR / INCI: Cosmetic ingredients (Oxyquinoline) -> CIR (Cosmetic Ingredient Review); CIR / INCI: Stabilizing.

Is 8-Hydroxyquinoline classified as hazardous?

0.6% of GHS notifications report no hazard classification (2 of 343).

What are the key physical properties of 8-Hydroxyquinoline?

Boiling Point: 513 °F at 760 mmHg (NTP, 1992); Boiling Point: 267; Boiling Point: Approx 267 °C; Boiling Point: 267 °C @760 [mm Hg].

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.