6-O-去甲基多奈哌齐

Description

6-O-DESMETHYL DONEPEZIL · CAS 120013-56-1 · C23H27NO3. UNII 556XXE4I5F.

Identification

CAS Registry Number	120013-56-1
PubChem CID	14553555
Molecular formula	C23H27NO3
IUPAC name	2-[(1-benzylpiperidin-4-yl)methyl]-6-hydroxy-5-methoxy-2,3-dihydroinden-1-one
UNII (FDA)	556XXE4I5F

Computed Descriptors

Molecular Weight	365.5
XLogP3	3.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	5
Exact Mass	365.19909372
Monoisotopic Mass	365.19909372
Topological Polar Surface Area	49.8
Heavy Atom Count	27
Formal Charge	0

Documented Uses

• 6-O-Desmethyl Donepezil has known human metabolites that include (2S,3S,4S,5R)-6-[[2-[(1-benzylpiperidin-4-yl)methyl]-6-methoxy-3-oxo-1,2-dihydroinden-5-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.
• 6-O-Desmethyl Donepezil is a known human metabolite of donepezil.

Synonyms

6-o-Desmethyldonepezil; Donepezil (m1); Donepezil (metabolite m1); UNII-556XXE4I5F; 556XXE4I5F; 1-Benzyl-4-((6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methyl)piperidine; 1H-Inden-1-one, 2,3-dihydro-6-hydroxy-5-methoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-; DTXSID60561627; 2-[(1-benzylpiperidin-4-yl)methyl]-6-hydroxy-5-methoxy-2,3-dihydro-1H-inden-1-one; 2-((1-benzylpiperidin-4-yl)methyl)-6-hydroxy-5-methoxy-2,3-dihydro-1h-inden-1-one; 1H-Inden-1-one, 2,3-dihydro-6-hydroxy-5-methoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-; RefChem:105140; DTXCID70512403; 6-O-Desmethyl Donepezil; 120013-56-1; Donepezil Impurity 5

Frequently Asked Questions

What are the CAS number and molecular formula of 6-O-DESMETHYL DONEPEZIL?

CAS 120013-56-1; molecular formula C23H27NO3; molecular weight — g/mol.

What other names is 6-O-DESMETHYL DONEPEZIL known by?

6-o-Desmethyldonepezil, Donepezil (m1), Donepezil (metabolite m1), UNII-556XXE4I5F, 556XXE4I5F, 1-Benzyl-4-((6-hydroxy-5-methoxy-1-oxo-indan-2-yl)methyl)piperidine.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.