6-甲硫基嘌呤核苷

Description

6-methylmercaptopurine riboside · CAS 342-69-8 · C11H14N4O4S. UNII Y5G39SHR0V. Melting Point: 164; Solubility: 5 to 10 mg/mL at 66 °F (NTP, 1992); Solubility: DMA 167 (mg/mL).

Identification

CAS Registry Number	342-69-8
PubChem CID	9570
Molecular formula	C11H14N4O4S
IUPAC name	(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-methylsulfanylpurin-9-yl)oxolane-3,4-diol
UNII (FDA)	Y5G39SHR0V

Computed Descriptors

Molecular Weight	298.32
XLogP3	0.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	3
Exact Mass	298.07357611
Monoisotopic Mass	298.07357611
Topological Polar Surface Area	139
Heavy Atom Count	20
Formal Charge	0

Physical & Chemical Properties

Melting Point	164
Solubility	5 to 10 mg/mL at 66 °F (NTP, 1992)
Solubility	DMA 167 (mg/mL)
Solubility	50% DMF 50 (mg/mL)
Solubility	H 25 (mg/mL)
LogP	0.09
Optical Rotation	(c = 1, H2O) [a]22 D = - 58.0 ± 2

Physical description & handling notes

• 6-methylmercaptopurine riboside is a white powder. (NTP, 1992)
• Propylene glycol 6 (mg/mL)
• Bulk: The compound is stable to light and air, mildly decomposed by heat and acid, and is totally degraded by base and peroxidant (HPLC). Solution: A saturated solution at room temperature showed no detectable decomposition after 10 days (paper chromatography).

Synonyms

6-Methylmercaptopurine riboside; 342-69-8; METHYLTHIOINOSINE; 6-Methylthiopurine riboside; MMPR; Me6MPR; 6-Methyl MP riboside; 6-Methyl MP-riboside; 6-MMPR; 6-Methylthioinosine; 6-Methylmercaptopurine ribonucleoside; Methylmercaptopurine riboside; 6-(Methylthio)purine ribonucleoside; Inosine, 6-S-methyl-6-thio-; 6-S-methyl-6-thioinosine; 6-Methyl-9-ribofuranosylpurine-6-thiol

Frequently Asked Questions

What are the CAS number and molecular formula of 6-methylmercaptopurine riboside?

CAS 342-69-8; molecular formula C11H14N4O4S; molecular weight — g/mol.

What other names is 6-methylmercaptopurine riboside known by?

6-Methylmercaptopurine riboside, 342-69-8, METHYLTHIOINOSINE, 6-Methylthiopurine riboside, MMPR, Me6MPR.

What are the key physical properties of 6-methylmercaptopurine riboside?

Melting Point: 164; Solubility: 5 to 10 mg/mL at 66 °F (NTP, 1992); Solubility: DMA 167 (mg/mL); Solubility: 50% DMF 50 (mg/mL).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.