5-(N-ethyl-N-isopropyl)-amiloride

Independent reference data for 5-(N-ethyl-N-isopropyl)-amiloride (CAS 1154-25-2), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Documented uses on record

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.

Synonyms and trade names

EIPA; 1154-25-2; Ethylisopropylamiloride; 5-(Ethylisopropyl)amiloride; Ethyl isopropyl amiloride; DTXSID80151084; VW50CE070T; 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide; N-Amidino-3-amino-5-ethylisopropylamino-6-chloropyrazine carboxamide; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-(ethyl(1-methylethyl)amino)pyrazinecarboxamide; MH-12-43; CHEBI:136538; L-593754; Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(ethyl(1-methylethyl)amino)-; 3-amino-6-chloro-N-(diaminomethylidene)-5-(ethyl(propan-2-yl)amino)pyrazine-2-carboxamide; RefChem:596785

GHS hazard classification

Reported hazard statements	H315 (100%), H319 (100%), H335 (100%)

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

What the public record says

5-(N-ethyl-N-isopropyl)-amiloride · CAS 1154-25-2 · C11H18ClN7O. UNII VW50CE070T.

Source: PubChem / Wikidata; the batch COA governs where values differ.