5-(N-乙基-N-异丙基)-阿米洛利

Description

5-(N-ethyl-N-isopropyl)-amiloride · CAS 1154-25-2 · C11H18ClN7O. UNII VW50CE070T.

Identification

Computed Descriptors

GHS Hazard Classification

Documented Uses

• Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
• Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.
• A subclass of sodium channel blockers that are specific for ACID-SENSING SODIUM CHANNELS.
• A subclass of sodium channel blockers that are specific for EPITHELIAL SODIUM CHANNELS.

Synonyms

EIPA; 1154-25-2; Ethylisopropylamiloride; 5-(Ethylisopropyl)amiloride; Ethyl isopropyl amiloride; DTXSID80151084; VW50CE070T; 3-amino-6-chloro-N-(diaminomethylidene)-5-[ethyl(propan-2-yl)amino]pyrazine-2-carboxamide; N-Amidino-3-amino-5-ethylisopropylamino-6-chloropyrazine carboxamide; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-(ethyl(1-methylethyl)amino)pyrazinecarboxamide; MH-12-43; CHEBI:136538; L-593754; Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-(ethyl(1-methylethyl)amino)-; 3-amino-6-chloro-N-(diaminomethylidene)-5-(ethyl(propan-2-yl)amino)pyrazine-2-carboxamide; RefChem:596785

Frequently Asked Questions

What are the CAS number and molecular formula of 5-(N-ethyl-N-isopropyl)-amiloride?

CAS 1154-25-2; molecular formula C11H18ClN7O; molecular weight — g/mol.

What other names is 5-(N-ethyl-N-isopropyl)-amiloride known by?

EIPA, 1154-25-2, Ethylisopropylamiloride, 5-(Ethylisopropyl)amiloride, Ethyl isopropyl amiloride, DTXSID80151084.

Is 5-(N-ethyl-N-isopropyl)-amiloride classified as hazardous?

Hazard statements reported: H315, H319, H335.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.