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5-溴-2'-脱氧尿苷

CAS 59-14-3C9H11BrN2O5MW 307.10

济南圣和化工主营供应 5-溴-2'-脱氧尿苷(CAS 59-14-3),归类于有机化学品,分子式 C9H11BrN2O5,分子量 307.10。我们面向国内化工贸易与生产企业提供稳定的现货供应,报价响应快,支持对公转账并可开具增值税发票。

产品概览

CAS号59-14-3
分子式C9H11BrN2O5
分子量307.10
熔点365 to 369 °F (NTP, 1992)
LogPlog Kow = -0.29
纯度按批次COA提供(不公开发布)
包装按订单/批次确认(不公开发布)
应用领域有机化学品
类别有机化学品

应用领域

有机化学品

5-溴-2'-脱氧尿苷主要应用于有机化学品。具体使用工况下的添加量与规格要求,欢迎与技术团队沟通确认。

包装与储存

包装规格按订单/批次确认(不公开发布)
纯度规格按批次COA提供(不公开发布)
储存条件密封、阴凉干燥处保存
运输常规化工运输
样品可协商提供
交期现货/按订单安排

采购提示:本产品按按订单/批次确认(不公开发布)起订发货,收到货物后请先核对包装完好性再行入库。储存条件为阴凉干燥、密封保存;如需 MSDS 或运输说明,可在询价时一并索取。

质量与文件

每批产品随货提供 COA(分析证书);可按需提供 MSDS/技术数据表及第三方检测报告。纯度与包装以批次 COA 及订单确认为准。

关于供应商

选择 济南圣和化工有限公司 的理由:产品信息透明(含 CAS、分子式、理化参数)、报价响应快(一个工作日内)、单证齐全(COA/MSS/质检资料按需提供)、支持批量与长期协议供货。如需 5-溴-2'-脱氧尿苷 以外的配套原料,也欢迎一并列出需求清单。

常见问题

5-溴-2'-脱氧尿苷 的 CAS 号是多少?

5-溴-2'-脱氧尿苷 的 CAS 号为 59-14-3。

该产品的纯度和包装规格是什么?

常规纯度规格为 按批次COA提供(不公开发布),包装为 按订单/批次确认(不公开发布),随货提供 COA。

5-溴-2'-脱氧尿苷 有什么用途?

主要应用于有机化学品。

如何购买或获取报价?

请发送邮件至 info@591daili.com 或通过 WhatsApp 联系,注明产品名称、CAS 号与需求数量,一个工作日内回复报价。供应商:济南圣和化工有限公司。

PubChem 公开数据

Description

5-Bromo-2'-Deoxyuridine · CAS 59-14-3 · C9H11BrN2O5. UNII G34N38R2N1. Melting Point: 365 to 369 °F (NTP, 1992); Melting Point: 187-189 °C; Solubility: 10 to 50 mg/mL at 72 °F (NTP, 1992).

Identification

CAS Registry Number59-14-3
PubChem CID6035
Molecular formulaC9H11BrN2O5
IUPAC name5-bromo-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
UNII (FDA)G34N38R2N1

Computed Descriptors

Molecular Weight307.10
XLogP3-0.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass305.98513
Monoisotopic Mass305.98513
Topological Polar Surface Area99.1
Heavy Atom Count17
Formal Charge0

Physical & Chemical Properties

Melting Point365 to 369 °F (NTP, 1992)
Melting Point187-189 °C
Solubility10 to 50 mg/mL at 72 °F (NTP, 1992)
SolubilityWater 10 - 20 (mg/mL)
Solubility1 N NaOH > 400 (mg/mL)
SolubilityAcetone ~ 4 (mg/mL)
LogPlog Kow = -0.29
LogP-0.29

Physical description & handling notes

  • 5-bromo-2'-deoxyuridine is a white crystalline powder. (NTP, 1992)
  • Crystals from absolute ethanol
  • Dimethylacetamide ~ 200 (mg/mL)
  • Dimethylsulfoxide ~ 160 (mg/mL)
  • Bulk: The bulk drug should be stored in tightly closed containers at controlled room temperature. Solution: BUdR solutions (0.5 and 25 mg/mL) are stable for at least seven days at room temperature.
  • (c = 1, 0.1 N NaOH) [a]20 D = +31 ± 1°

GHS Hazard Classification

Reported hazard statementsH340 (83.3%), H341 (13%), H361 (79.6%)

H340 (83.3%): May cause genetic defects [Danger Germ cell mutagenicity]

H341 (13%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]

Documented Uses

  • A drug that makes cancer cells more sensitive to radiation and is also used as a diagnostic agent to determine how fast cancer cells grow.
  • A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
  • A thymidine analog that incorporates /into/ DNA of dividing cells during the S-phase of the cell cycle. ... However, BrdU is not a marker of the S-phase of the cell cycle. As a thymidine analog, it is a marker of DNA synthesis. BrdU immunohistochemistry has been instrumental for the study of the development of the nervous system, and to confirm that neurogenesis occurs in the adult mammalian brain, including in human. ... BrdU labeling is currently the most used technique for studying adult neurogenesis in situ.
  • The standard method for assessment of cell proliferation in paraffin-embedded tissue sections is 5-bromodeoxyuridine (BrdU) immunohistochemistry (IHC). BrdU can be administered to laboratory animals via IP injections, is readily incorporated into nuclei during the DNA synthetic phase of the cell cycle, and is detected with an anti-BrdU antibody. ...
  • Laboratory chemical used as a mutagen in mutagenesis experiments. It is more commonly used in the detection of proliferating cells in living tissues.
  • Treatment of an aqueous solution of /deoxyuridine/ with saturated bromine water at 0 °C followed by removal of excess /bromine/ by suction, concentration at 30 °C, refluxing with /ethanol/, concentration at <35 °C, and crystallization from absolute /ethanol/ gave 60% /5-bromodeoxyuridine/ (purity 99%).

Synonyms

5-BROMO-2'-DEOXYURIDINE; 59-14-3; Broxuridine; Bromodeoxyuridine; 5-Bromodeoxyuridine; BRDU; BUDR; 5-Bromo-2-deoxyuridine; Radibud; Broxuridina; 5-Bdu; 5-Bromouracil deoxyriboside; Bromouracil deoxyriboside; 5-Bromodesoxyuridine; Broxuridinum; 5-Bromouracil-2-deoxyriboside

Frequently Asked Questions

What are the CAS number and molecular formula of 5-Bromo-2'-Deoxyuridine?

CAS 59-14-3; molecular formula C9H11BrN2O5; molecular weight — g/mol.

What other names is 5-Bromo-2'-Deoxyuridine known by?

5-BROMO-2'-DEOXYURIDINE, 59-14-3, Broxuridine, Bromodeoxyuridine, 5-Bromodeoxyuridine, BRDU.

Is 5-Bromo-2'-Deoxyuridine classified as hazardous?

Hazard statements reported: H340, H341, H361.

What are the key physical properties of 5-Bromo-2'-Deoxyuridine?

Melting Point: 365 to 369 °F (NTP, 1992); Melting Point: 187-189 °C; Solubility: 10 to 50 mg/mL at 72 °F (NTP, 1992); Solubility: Water 10 - 20 (mg/mL).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.

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English page: 5-Bromo-2'-Deoxyuridine

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