5,6-trans-Ergocalciferol (CAS 51744-66-2) — formula C28H44O, molecular weight 396.6; category organic chemicals.
| CAS Number | 51744-66-2 |
|---|---|
| Molecular Formula | C28H44O |
| Molecular Weight | 396.6 |
| Melting Point | 239 to 244 °F (EPA, 1998) |
| LogP | 7.4 |
| Applications | Uses: Synthetic form of vitamin D used as a rodenticide and therapeutic vitamin, [Merck Index] Used as a nutritional supplement, [FDA], No active pesticide product registrations in the US, [NPIRS], MEDICATION, MEDICATION (VET), Rodenticide., For use in the management of hypocalcemia and its clinical manifestations in patients with hypoparathyroidism, as well as for the treatment of familial hypophosphatemia (vitamin D resistant rickets). This drug has also been used in the treatment of nutritional rickets or osteomalacia, vitamin D dependent rickets, rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy, early renal osteodystrophy, osteoporosis (in conjunction with calcium), and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis)., Household Products: Information on 1 consumer products that contain Ergocalciferol in the following categories is provided:, • Personal Care, Methods of Manufacturing:, Is, the synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. ... The best wavelengths for production of vitamin D2 seem to be from 275 to 300 nm ... Prepn by electron bombardment of ergosterol using longer waves ... ., Usually obtained from yeast which synthesizes it from simple sugars such as glucose., Formulations, Preparations: Ergocalciferol capsules usually consist of the drug in an edible oil solution encapsulated with gelatin. Commercially available ergocalciferol solution is a clear solution of the drug in an edible vegetable oil or in propylene glycol. Ergocalciferol injection is a sterile solution of the drug in sesame oil., Ergocalciferol is also commercially available in combination with other vitamins and minerals, analgesic-antipyretics, amino acids, infant formulas, laxatives, and protein supplements., Parenteral: Injection (for IM use only): 12.5 mg (500, 000 units) per mL, Calciferol (in oil), (Schwarz), Ergocalciferol (calciferol, Drisdol) is pure vitamin D2. ... Available in capsules or tablets that contain 1.25 mg (50, 000 USP units) each. An oral solution (8, 000 units, mL) of the vitamin in propylene glycol is also available. An injection in oil (500, mL) is available for im administration. ... Dihydrotachysterol (DHT, hytakerol) is the pure crystalline compound obtained by reduction of vitamin D2 ... Available as tablets (0.125 to 0.4 mg), capsules (0.125 mg), an oral soln (0.2 mg, mL) & a soln in oil (0.2 mg, mL)., For more Formulations, Preparations (Complete) data for VITAMIN D2 (7 total), please visit the HSDB record page., U.S. Imports: (1984) 9.16X10+7 g, Vitamin D-2 and D-3, synthetic, General Manufacturing Information: Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R, 3aS, 7aR)-octahydro-7a-methyl-1-[(1R, 2E, 4R)-1, 4, 5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-, (1S, 3Z)-: ACTIVE, Information available in 2004 indicated that Ergocalciferol was used in the manufacture of pharmaceutical preparations in the following countries: Argentina, Australia, Austria, Brazil, Canada, Chile, Czech Republic, Denmark, Ecuador, Finland, France, Germany, Greece, Hong Kong, Ireland, Israel, Italy, Luxembourg, Malaysia, Mexico, Norway, Portugal, Romania, Slovakia, South Africa, Spain, Switzerland, Thailand, United Kingdom, USA (1, 2), International & USP units of vitamin D are equivalent in activity to 0.025 ug of crystalline vitamin D2., Ergosterol, which is present in plants, is provitamin for vitamin D2 (calciferol). ... Vitamin D2 is active constituent in a number of commercial vitamin preparations as well as in irradiated bread & irradiated milk., Vitamin D2 crystals have a potency of 40 units of vitamin D (USP), ug., Because of vitamin D2's sensitivity to oxygen and light, USP allows traces of antioxidants in crystalline compound. |
| Category | Organic Chemicals |
Documented applications: Uses: Synthetic form of vitamin D used as a rodenticide and therapeutic vitamin, [Merck Index] Used as a nutritional supplement, [FDA], No active pesticide product registrations in the US, [NPIRS], MEDICATION, MEDICATION (VET), Rodenticide., For use in the management of hypocalcemia and its clinical manifestations in patients with hypoparathyroidism, as well as for the treatment of familial hypophosphatemia (vitamin D resistant rickets). This drug has also been used in the treatment of nutritional rickets or osteomalacia, vitamin D dependent rickets, rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy, early renal osteodystrophy, osteoporosis (in conjunction with calcium), and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis)., Household Products: Information on 1 consumer products that contain Ergocalciferol in the following categories is provided:, • Personal Care, Methods of Manufacturing:, Is, the synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. ... The best wavelengths for production of vitamin D2 seem to be from 275 to 300 nm ... Prepn by electron bombardment of ergosterol using longer waves ... ., Usually obtained from yeast which synthesizes it from simple sugars such as glucose., Formulations, Preparations: Ergocalciferol capsules usually consist of the drug in an edible oil solution encapsulated with gelatin. Commercially available ergocalciferol solution is a clear solution of the drug in an edible vegetable oil or in propylene glycol. Ergocalciferol injection is a sterile solution of the drug in sesame oil., Ergocalciferol is also commercially available in combination with other vitamins and minerals, analgesic-antipyretics, amino acids, infant formulas, laxatives, and protein supplements., Parenteral: Injection (for IM use only): 12.5 mg (500, 000 units) per mL, Calciferol (in oil), (Schwarz), Ergocalciferol (calciferol, Drisdol) is pure vitamin D2. ... Available in capsules or tablets that contain 1.25 mg (50, 000 USP units) each. An oral solution (8, 000 units, mL) of the vitamin in propylene glycol is also available. An injection in oil (500, mL) is available for im administration. ... Dihydrotachysterol (DHT, hytakerol) is the pure crystalline compound obtained by reduction of vitamin D2 ... Available as tablets (0.125 to 0.4 mg), capsules (0.125 mg), an oral soln (0.2 mg, mL) & a soln in oil (0.2 mg, mL)., For more Formulations, Preparations (Complete) data for VITAMIN D2 (7 total), please visit the HSDB record page., U.S. Imports: (1984) 9.16X10+7 g, Vitamin D-2 and D-3, synthetic, General Manufacturing Information: Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R, 3aS, 7aR)-octahydro-7a-methyl-1-[(1R, 2E, 4R)-1, 4, 5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-, (1S, 3Z)-: ACTIVE, Information available in 2004 indicated that Ergocalciferol was used in the manufacture of pharmaceutical preparations in the following countries: Argentina, Australia, Austria, Brazil, Canada, Chile, Czech Republic, Denmark, Ecuador, Finland, France, Germany, Greece, Hong Kong, Ireland, Israel, Italy, Luxembourg, Malaysia, Mexico, Norway, Portugal, Romania, Slovakia, South Africa, Spain, Switzerland, Thailand, United Kingdom, USA (1, 2), International & USP units of vitamin D are equivalent in activity to 0.025 ug of crystalline vitamin D2., Ergosterol, which is present in plants, is provitamin for vitamin D2 (calciferol). ... Vitamin D2 is active constituent in a number of commercial vitamin preparations as well as in irradiated bread & irradiated milk., Vitamin D2 crystals have a potency of 40 units of vitamin D (USP), ug., Because of vitamin D2's sensitivity to oxygen and light, USP allows traces of antioxidants in crystalline compound..
5,6-trans-Ergocalciferol is a carbon-based organic compound with CAS registry number 51744-66-2 and molecular formula C28H44O (molecular weight 396.6), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 51744-66-2
Its molecular formula C28H44O comprises 28 C, 44 H, 1 O atoms.
Also known as: 5,6-trans-Ergocalciferol · 麦角钙化醇EP杂质A
Category: organic chemicals
The CAS registry number of 5,6-trans-Ergocalciferol is 51744-66-2.
Molecular formula C28H44O, molecular weight 396.6.
It is also registered under: 5,6-trans-Ergocalciferol, 麦角钙化醇EP杂质A.
Recorded applications: Uses: Synthetic form of vitamin D used as a rodenticide and therapeutic vitamin, [Merck Index] Used as a nutritional supplement, [FDA], No active pesticide product registrations in the US, [NPIRS], MEDICATION, MEDICATION (VET), Rodenticide., For use in the management of hypocalcemia and its clinical manifestations in patients with hypoparathyroidism, as well as for the treatment of familial hypophosphatemia (vitamin D resistant rickets). This drug has also been used in the treatment of nutritional rickets or osteomalacia, vitamin D dependent rickets, rickets or osteomalacia secondary to long-term high dose anticonvulsant therapy, early renal osteodystrophy, osteoporosis (in conjunction with calcium), and hypophosphatemia associated with Fanconi syndrome (with treatment of acidosis)., Household Products: Information on 1 consumer products that contain Ergocalciferol in the following categories is provided:, • Personal Care, Methods of Manufacturing:, Is, the synthetic form of vitamin D. Prepared from ergosterol by UV irradiation in a suitable solvent. ... The best wavelengths for production of vitamin D2 seem to be from 275 to 300 nm ... Prepn by electron bombardment of ergosterol using longer waves ... ., Usually obtained from yeast which synthesizes it from simple sugars such as glucose., Formulations, Preparations: Ergocalciferol capsules usually consist of the drug in an edible oil solution encapsulated with gelatin. Commercially available ergocalciferol solution is a clear solution of the drug in an edible vegetable oil or in propylene glycol. Ergocalciferol injection is a sterile solution of the drug in sesame oil., Ergocalciferol is also commercially available in combination with other vitamins and minerals, analgesic-antipyretics, amino acids, infant formulas, laxatives, and protein supplements., Parenteral: Injection (for IM use only): 12.5 mg (500, 000 units) per mL, Calciferol (in oil), (Schwarz), Ergocalciferol (calciferol, Drisdol) is pure vitamin D2. ... Available in capsules or tablets that contain 1.25 mg (50, 000 USP units) each. An oral solution (8, 000 units, mL) of the vitamin in propylene glycol is also available. An injection in oil (500, mL) is available for im administration. ... Dihydrotachysterol (DHT, hytakerol) is the pure crystalline compound obtained by reduction of vitamin D2 ... Available as tablets (0.125 to 0.4 mg), capsules (0.125 mg), an oral soln (0.2 mg, mL) & a soln in oil (0.2 mg, mL)., For more Formulations, Preparations (Complete) data for VITAMIN D2 (7 total), please visit the HSDB record page., U.S. Imports: (1984) 9.16X10+7 g, Vitamin D-2 and D-3, synthetic, General Manufacturing Information: Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R, 3aS, 7aR)-octahydro-7a-methyl-1-[(1R, 2E, 4R)-1, 4, 5-trimethyl-2-hexen-1-yl]-4H-inden-4-ylidene]ethylidene]-, (1S, 3Z)-: ACTIVE, Information available in 2004 indicated that Ergocalciferol was used in the manufacture of pharmaceutical preparations in the following countries: Argentina, Australia, Austria, Brazil, Canada, Chile, Czech Republic, Denmark, Ecuador, Finland, France, Germany, Greece, Hong Kong, Ireland, Israel, Italy, Luxembourg, Malaysia, Mexico, Norway, Portugal, Romania, Slovakia, South Africa, Spain, Switzerland, Thailand, United Kingdom, USA (1, 2), International & USP units of vitamin D are equivalent in activity to 0.025 ug of crystalline vitamin D2., Ergosterol, which is present in plants, is provitamin for vitamin D2 (calciferol). ... Vitamin D2 is active constituent in a number of commercial vitamin preparations as well as in irradiated bread & irradiated milk., Vitamin D2 crystals have a potency of 40 units of vitamin D (USP), ug., Because of vitamin D2's sensitivity to oxygen and light, USP allows traces of antioxidants in crystalline compound..
Category: Organic Chemicals.
Independent reference data for 5,6-trans-Ergocalciferol (CAS 51744-66-2), compiled from public chemistry databases.
| CAS 号 | 51744-66-2 |
|---|---|
| PubChem CID | 6536972 |
| 分子式 | C28H44O |
| IUPAC 名称 | (1S,3E)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol |
| UNII（FDA） | LYM8W766XP |
| Molecular Weight | 396.6 |
|---|---|
| XLogP3 | 7.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 5 |
| Exact Mass | 396.339216023 |
| Monoisotopic Mass | 396.339216023 |
| Topological Polar Surface Area | 20.2 |
| Heavy Atom Count | 29 |
| Melting Point | 239 to 244 °F (EPA, 1998) |
|---|---|
| Melting Point | 116.5 °C |
| Solubility | In water, 50 mg/L at 25 °C |
5,6-trans-Vitamin D2; 51744-66-2; LYM8W766XP; (5E,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3beta-ol; RefChem:1050610; 5,6-trans-Ergocalciferol; trans-Vitamin D2; 5,6-trans-Ergocalcifero; 50-14-6; DTXCID70233; (5E,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol; CAS-50-14-6; NCGC00166307-01; (5E)-vitamin D2; UNII-LYM8W766XP; SCHEMBL1651665
| 法规与食品接触 | FDA Substance added to food: NUTRIENT SUPPLEMENT VITAMIN D-2 |
|---|
| 已通报的危害声明 | H301, H311, H330, H372, H300, H310, H413 (41.8%) |
|---|
麦角钙化醇EP A · CAS 51744-66-2 · C28H44O。 UNII LYM8W766XP。熔点：239 至 244 °F（EPA，1998）；熔点：116.5℃；溶解度：水中，25 °C 时为 50 mg/L。
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 麦角钙化醇EP杂质A