4-hydroxytamoxifen

Description

4-hydroxytamoxifen · CAS 68047-06-3 · C26H29NO2. UNII 95K54647BZ.

Identification

Computed Descriptors

GHS Hazard Classification

Documented Uses

• For the potential treatment of menstrual-cycle related mastalgia, fibrocystic breast disease, breast disease, gynecomastia and Keloid scarring.
• Substances that inhibit or prevent the proliferation of NEOPLASMS.
• Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds.
• A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
• Absorbed following topical application.
• 4-Hydroxytamoxifen has known human metabolites that include Tamoxifen 4-O-glucuronide, Endoxifen, Tamoxifen 4-O-sulfate, and 3,4-Dihydroxy-Tamoxifen.

Synonyms

4-Hydroxytamoxifen; (Z)-4-Hydroxytamoxifen; 68047-06-3; Hydroxytamoxifen; DTXSID7022384; 4-OHT hydrotamoxifen; 95K54647BZ; 4-[(Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol; 4-[(1Z)-1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol; DTXCID802384; ICI-79280; DTXCID0028161; DTXSID3037094; 4-((Z)-1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-enyl)phenol; 4OH-tamoxifen; 4-((1Z)-1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol

Frequently Asked Questions

What are the CAS number and molecular formula of 4-hydroxytamoxifen?

CAS 68047-06-3; molecular formula C26H29NO2; molecular weight — g/mol.

What other names is 4-hydroxytamoxifen known by?

4-Hydroxytamoxifen, (Z)-4-Hydroxytamoxifen, 68047-06-3, Hydroxytamoxifen, DTXSID7022384, 4-OHT hydrotamoxifen.

Is 4-hydroxytamoxifen classified as hazardous?

Hazard statements reported: H302, H312, H332, H361.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.