4-ethoxyphenylurea（CAS 150-69-6）：分子式 C9H12N2O2、分子量 180.20。
| CAS号 | 150-69-6 |
|---|---|
| 分子式 | C9H12N2O2 |
| 分子量 | 180.20 |
| 熔点 | 343 to 345 °F (NTP, 1992) |
| LogP | 1 |
| 应用领域 | Uses: Artificial sweetening agent、prohibited by FDA for use in foods.、Non-nutritive sweetener、Use Classification: Food Additives -> SWEETENER -> JECFA Functional Classes、Food Additives -> SWEETENER -> JECFA Functional Classes、Methods of Manufacturing: From p-aminophenol、... Produced from the addition of potassium cyanate to p-phenetidine hydrochloride in aqueous solution at room temperature or from mixing urea and p-phenetidine hydrochloride to a mixture of hydrochloric acid and glacial acetic acid.、Made by treating p-phenetidine with phosgene and then with ammonia.、General Manufacturing Information: Dulcin achieved some practical importance as a sweetener、despite safety concerns. It was blended with saccharin or sodium saccharin in order to mask the aftertaste of saccharin. As some dulcin metabolites were considered potentially hazardous、it is now banned in most countries.、Compared with dilute sucrose solutions、it is approximately 250 times sweeter. Sweetness characteristics are good. |
登记用途：Uses: Artificial sweetening agent、prohibited by FDA for use in foods.、Non-nutritive sweetener、Use Classification: Food Additives -> SWEETENER -> JECFA Functional Classes、Food Additives -> SWEETENER -> JECFA Functional Classes、Methods of Manufacturing: From p-aminophenol、... Produced from the addition of potassium cyanate to p-phenetidine hydrochloride in aqueous solution at room temperature or from mixing urea and p-phenetidine hydrochloride to a mixture of hydrochloric acid and glacial acetic acid.、Made by treating p-phenetidine with phosgene and then with ammonia.、General Manufacturing Information: Dulcin achieved some practical importance as a sweetener、despite safety concerns. It was blended with saccharin or sodium saccharin in order to mask the aftertaste of saccharin. As some dulcin metabolites were considered potentially hazardous、it is now banned in most countries.、Compared with dilute sucrose solutions、it is approximately 250 times sweeter. Sweetness characteristics are good.。
4-ethoxyphenylurea 是一种化工化合物，登记 CAS 号为 150-69-6，分子式 C9H12N2O2（分子量 180.20）。
登记 CAS 号：150-69-6
其分子式 C9H12N2O2 由 9 个碳、12 个氢、2 个氮、2 个氧 组成。
别名/同义词：4-ethoxyphenylurea · Dulcin
4-ethoxyphenylurea 的 CAS 登记号为 150-69-6。
分子式 C9H12N2O2，分子量 180.20。
别名/同义词：4-ethoxyphenylurea、Dulcin。
登记用途：Uses: Artificial sweetening agent、prohibited by FDA for use in foods.、Non-nutritive sweetener、Use Classification: Food Additives -> SWEETENER -> JECFA Functional Classes、Food Additives -> SWEETENER -> JECFA Functional Classes、Methods of Manufacturing: From p-aminophenol、... Produced from the addition of potassium cyanate to p-phenetidine hydrochloride in aqueous solution at room temperature or from mixing urea and p-phenetidine hydrochloride to a mixture of hydrochloric acid and glacial acetic acid.、Made by treating p-phenetidine with phosgene and then with ammonia.、General Manufacturing Information: Dulcin achieved some practical importance as a sweetener、despite safety concerns. It was blended with saccharin or sodium saccharin in order to mask the aftertaste of saccharin. As some dulcin metabolites were considered potentially hazardous、it is now banned in most countries.、Compared with dilute sucrose solutions、it is approximately 250 times sweeter. Sweetness characteristics are good.。
4-ethoxyphenylurea（CAS 150-69-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 150-69-6 |
|---|---|
| PubChem CID | 9013 |
| Molecular formula | C9H12N2O2 |
| IUPAC name | (4-ethoxyphenyl)urea |
| UNII (FDA) | 8U78KF577Z |
| Molecular Weight | 180.20 |
|---|---|
| XLogP3 | 1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 3 |
| Exact Mass | 180.089877630 |
| Monoisotopic Mass | 180.089877630 |
| Topological Polar Surface Area | 64.4 |
| Heavy Atom Count | 13 |
| Melting Point | 343 to 345 °F (NTP, 1992) |
|---|---|
| Melting Point | 173.5 °C |
| Melting Point | 173 - 174 °C |
| Solubility | In water, 1.21 g/L at 21 °C |
| Solubility | 1.21 mg/mL at 21 °C |
Dulcin; 150-69-6; 1-(4-Ethoxyphenyl)urea; (4-ethoxyphenyl)urea; N-(4-Ethoxyphenyl)urea; Sucrol; Valzin; p-Ethoxyphenylurea; Dulcine; Phenetolcarbamide; Suesstoff; p-Phenetolcarbamide; p-Phenetylurea; p-Phenetolecarbamide; 4-ETHOXYPHENYLUREA; p-Phenetolcarbamid
| Regulatory & Food Contact | FDA Substance added to food: NON-NUTRITIVE SWEETENER SWEETENER: Food Additives DULCIN--PROHIBITED NOT TO BE USED NMRS 44/TRS 383-JECFA 11/13 FAS 68.33/NMRS 44A-JECFA 11/100 |
|---|
| Reported hazard statements | H302 (50%), H315 (50%), H319 (50%) |
|---|
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
4-ethoxyphenylurea · CAS 150-69-6 · C9H12N2O2. UNII 8U78KF577Z. Melting Point: 343 to 345 °F (NTP, 1992); Melting Point: 173.5 °C; Melting Point: 173 - 174 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: 4-ethoxyphenylurea