4-chloropyridine

Description

4-chloropyridine · CAS 626-61-9 · C5H4ClN. UNII X97LKY9QS7. Boiling Point: 151 °C; Melting Point: -43.5 °C; Density: 1.2000 g/cu cm at 25 °C.

Identification

Computed Descriptors

Physical & Chemical Properties

Physical description & handling notes

• Liquid
• Slightly soluble in water
• Miscible with ethanol
• pKa = 3.84 (conjugate acid)

Documented Uses

• Reaction of 4-chloropyridine with mercaptoacetic acid gives pyridylmercaptoacetic acid, which is a precursor for cephalosporin antibiotics (e.g., cephapirin sodium salt).
• The 2- and 4-chloropyridines react with various nucleophiles to give alkyl ether, alkyl thioether, and alkylamine derivatives.
• The preparation of 2- and 4- chloropyridines from pyridinols is achieved by the use of halogenating reagents such as phosphoryl chloride.

Synonyms

4-CHLOROPYRIDINE; 626-61-9; DTXSID0052671; RefChem:522062; DTXCID608484; 210-956-2; Pyridine, 4-chloro-; 4-chloro-pyridine; MFCD00044570; CHEMBL5290039; EINECS 210-956-2; BRN 0105875; p-Chloropyridine; 4-chloro pyridine; 4- Chloropyridine; Trazodone Impurity 20

Frequently Asked Questions

What are the CAS number and molecular formula of 4-chloropyridine?

CAS 626-61-9; molecular formula C5H4ClN; molecular weight — g/mol.

What other names is 4-chloropyridine known by?

4-CHLOROPYRIDINE, 626-61-9, DTXSID0052671, RefChem:522062, DTXCID608484, 210-956-2.

What are the key physical properties of 4-chloropyridine?

Boiling Point: 151 °C; Melting Point: -43.5 °C; Density: 1.2000 g/cu cm at 25 °C; LogP: log Kow = 1.28.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.