3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine (CAS 877399-52-5) — formula C21H22Cl2FN5O, molecular weight 450.3; category organic chemicals.
| CAS Number | 877399-52-5 |
|---|---|
| Molecular Formula | C21H22Cl2FN5O |
| Molecular Weight | 450.3 |
| LogP | 1.83 |
| Category | Organic Chemicals |
3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine is a carbon-based organic compound with CAS registry number 877399-52-5 and molecular formula C21H22Cl2FN5O (molecular weight 450.3), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 877399-52-5
Its molecular formula C21H22Cl2FN5O comprises 21 C, 22 H, 2 Cl, 1 F, 5 N, 1 O atoms.
Also known as: 3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine · 克唑替尼
Category: organic chemicals
The CAS registry number of 3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine is 877399-52-5.
Molecular formula C21H22Cl2FN5O, molecular weight 450.3.
It is also registered under: 3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine, 克唑替尼.
Category: Organic Chemicals.
Independent reference data for 3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine (CAS 877399-52-5), compiled from public chemistry databases.
| CAS 号 | 877399-52-5 |
|---|---|
| PubChem CID | 11626560 |
| 分子式 | C21H22Cl2FN5O |
| IUPAC 名称 | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-ylpyrazol-4-yl)pyridin-2-amine |
| UNII（FDA） | 53AH36668S |
| Molecular Weight | 450.3 |
|---|---|
| XLogP3 | 3.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 449.1185439 |
| Monoisotopic Mass | 449.1185439 |
| Topological Polar Surface Area | 78 |
| Heavy Atom Count | 30 |
| LogP | 1.83 |
|---|
Crizotinib; 877399-52-5; PF-02341066; (R)-crizotinib; PF-2341066; Xalkori; PF 2341066; (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine; PF 02341066; crizotinibum; CHEBI:64310; PF2341066; 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine; 53AH36668S; NSC-756645; PF02341066
| 已通报的危害声明 | H317 (100%), H318 (38.7%), H319 (60%), H341 (100%), H400 (61.3%) |
|---|
克唑替尼 · CAS 877399-52-5 · C21H22Cl2FN5O. UNII 53AH36668S. LogP: 1.83.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 克唑替尼