2-Toluenesulfonamide (CAS 8013-74-9) — formula C7H9NO2S, molecular weight 171.22; category organic chemicals.
| CAS Number | 8013-74-9 |
|---|---|
| Molecular Formula | C7H9NO2S |
| Molecular Weight | 171.22 |
| Melting Point | 156.3 °C |
| Boiling Point | 214 °C at 10 mm Hg |
| LogP | log Kow = 0.84 |
| Applications | Uses: Used in mixtures with p-toluenesulfonamide as reactive plasticizer, Also used as a plasticizer for hot-melt adhesives and a chemical intermediate for fluorescent pigments and plasticizer resins, [HSDB] Used to make saccharin, [eChemPortal: SIDSUNEP] A contaminant of saccharin, [IARC], Plasticizer, Used in manufacture of saccharin., The ortho- and para-toluenesulfonamide mixture is used as a reactive plasticizer in hot-melt adhesives to improve the flow properties of thermosetting resins (e.g., melamine, urea and phenolic resins) and to impart flexibility to coatings based on resins made from casein, shellac, zein and soya protein., Ortho- and para-toluenesulfonamide mixture, ... carrier in fluorescent pigments., Industry Uses: Plasticizer, Methods of Manufacturing: ... obtained by treating 2-methylbenzenesulfonyl chloride with aqueous ammonia (d 0.910). Purified by fractional precipitation: hydrochloric acid is added to a solution which has been rendered alkaline with sodium hydroxide, the impurities are precipitated first., REACTION OF O-TOLUENESULFONYL CHLORIDE WITH AMMONIA, U.S. Production: 2023: <75, 000 lb, 2022: 75, 000 - <500, 2021: <75, 2020: 75, (1979) MORE THAN 2.27X10+6 G (O-, P- MIXTURE), (1981) MORE THAN 2.27X10+6 G (O-, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzenesulfonamide, 2-methyl:, Table: National Aggregate Production Volume (pounds) [Table#5315], U.S. Imports: (1981) 1.31X10+7 GRAMS (PRINCPL CUSTMS DISTS), (1982) 1.24X10+7 GRAMS (PRINCPL CUSTMS DISTS), General Manufacturing Information: Plastics Material and Resin Manufacturing, Benzenesulfonamide, 2-methyl-: ACTIVE, ortho-Toluenesulfonamide is not produced commercially as a separate chemical in USA, however, a product consisting of a mixture of unknown proportions of the ortho- and para-isomers of toluenesulfonamide is produced in the USA., Until 1972, ortho-toluenesulfonamide was used in the USA as a chemical intermediate for the commercial production of saccharin. |
| Category | Organic Chemicals |
Documented applications: Uses: Used in mixtures with p-toluenesulfonamide as reactive plasticizer, Also used as a plasticizer for hot-melt adhesives and a chemical intermediate for fluorescent pigments and plasticizer resins, [HSDB] Used to make saccharin, [eChemPortal: SIDSUNEP] A contaminant of saccharin, [IARC], Plasticizer, Used in manufacture of saccharin., The ortho- and para-toluenesulfonamide mixture is used as a reactive plasticizer in hot-melt adhesives to improve the flow properties of thermosetting resins (e.g., melamine, urea and phenolic resins) and to impart flexibility to coatings based on resins made from casein, shellac, zein and soya protein., Ortho- and para-toluenesulfonamide mixture, ... carrier in fluorescent pigments., Industry Uses: Plasticizer, Methods of Manufacturing: ... obtained by treating 2-methylbenzenesulfonyl chloride with aqueous ammonia (d 0.910). Purified by fractional precipitation: hydrochloric acid is added to a solution which has been rendered alkaline with sodium hydroxide, the impurities are precipitated first., REACTION OF O-TOLUENESULFONYL CHLORIDE WITH AMMONIA, U.S. Production: 2023: <75, 000 lb, 2022: 75, 000 - <500, 2021: <75, 2020: 75, (1979) MORE THAN 2.27X10+6 G (O-, P- MIXTURE), (1981) MORE THAN 2.27X10+6 G (O-, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzenesulfonamide, 2-methyl:, Table: National Aggregate Production Volume (pounds) [Table#5315], U.S. Imports: (1981) 1.31X10+7 GRAMS (PRINCPL CUSTMS DISTS), (1982) 1.24X10+7 GRAMS (PRINCPL CUSTMS DISTS), General Manufacturing Information: Plastics Material and Resin Manufacturing, Benzenesulfonamide, 2-methyl-: ACTIVE, ortho-Toluenesulfonamide is not produced commercially as a separate chemical in USA, however, a product consisting of a mixture of unknown proportions of the ortho- and para-isomers of toluenesulfonamide is produced in the USA., Until 1972, ortho-toluenesulfonamide was used in the USA as a chemical intermediate for the commercial production of saccharin..
2-Toluenesulfonamide is a carbon-based organic compound with CAS registry number 8013-74-9 and molecular formula C7H9NO2S (molecular weight 171.22), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 8013-74-9
Its molecular formula C7H9NO2S comprises 7 C, 9 H, 1 N, 2 O, 1 S atoms.
Also known as: 2-Toluenesulfonamide · 2-甲苯磺酰胺
Category: organic chemicals
The CAS registry number of 2-Toluenesulfonamide is 8013-74-9.
Molecular formula C7H9NO2S, molecular weight 171.22.
It is also registered under: 2-Toluenesulfonamide, 2-甲苯磺酰胺.
Recorded applications: Uses: Used in mixtures with p-toluenesulfonamide as reactive plasticizer, Also used as a plasticizer for hot-melt adhesives and a chemical intermediate for fluorescent pigments and plasticizer resins, [HSDB] Used to make saccharin, [eChemPortal: SIDSUNEP] A contaminant of saccharin, [IARC], Plasticizer, Used in manufacture of saccharin., The ortho- and para-toluenesulfonamide mixture is used as a reactive plasticizer in hot-melt adhesives to improve the flow properties of thermosetting resins (e.g., melamine, urea and phenolic resins) and to impart flexibility to coatings based on resins made from casein, shellac, zein and soya protein., Ortho- and para-toluenesulfonamide mixture, ... carrier in fluorescent pigments., Industry Uses: Plasticizer, Methods of Manufacturing: ... obtained by treating 2-methylbenzenesulfonyl chloride with aqueous ammonia (d 0.910). Purified by fractional precipitation: hydrochloric acid is added to a solution which has been rendered alkaline with sodium hydroxide, the impurities are precipitated first., REACTION OF O-TOLUENESULFONYL CHLORIDE WITH AMMONIA, U.S. Production: 2023: <75, 000 lb, 2022: 75, 000 - <500, 2021: <75, 2020: 75, (1979) MORE THAN 2.27X10+6 G (O-, P- MIXTURE), (1981) MORE THAN 2.27X10+6 G (O-, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Benzenesulfonamide, 2-methyl:, Table: National Aggregate Production Volume (pounds) [Table#5315], U.S. Imports: (1981) 1.31X10+7 GRAMS (PRINCPL CUSTMS DISTS), (1982) 1.24X10+7 GRAMS (PRINCPL CUSTMS DISTS), General Manufacturing Information: Plastics Material and Resin Manufacturing, Benzenesulfonamide, 2-methyl-: ACTIVE, ortho-Toluenesulfonamide is not produced commercially as a separate chemical in USA, however, a product consisting of a mixture of unknown proportions of the ortho- and para-isomers of toluenesulfonamide is produced in the USA., Until 1972, ortho-toluenesulfonamide was used in the USA as a chemical intermediate for the commercial production of saccharin..
Category: Organic Chemicals.
Independent reference data for 2-Toluenesulfonamide (CAS 8013-74-9), compiled from public chemistry databases.
| CAS Registry Number | 8013-74-9 |
|---|---|
| PubChem CID | 6924 |
| Molecular formula | C7H9NO2S |
| IUPAC name | 2-methylbenzenesulfonamide |
| UNII (FDA) | R81Z6V889P |
| Molecular Weight | 171.22 |
|---|---|
| XLogP3 | 0.8 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 171.03539970 |
| Monoisotopic Mass | 171.03539970 |
| Topological Polar Surface Area | 68.5 |
| Heavy Atom Count | 11 |
| Boiling Point | 214 °C at 10 mm Hg |
|---|---|
| Boiling Point | >270 °C |
| Melting Point | 156.3 °C |
| Melting Point | 156 °C |
| Solubility | In water, 1.62X10+3 mg/L at 25 °C |
| Density | 1.46 g/cm³ |
| Vapor Pressure | 0.00006 [mmHg] |
| Vapor Pressure | 0.000306 [mmHg] |
| LogP | log Kow = 0.84 |
| LogP | 0.84 |
O-TOLUENESULFONAMIDE; 88-19-7; 2-Methylbenzenesulfonamide; 2-Toluenesulfonamide; Benzenesulfonamide, 2-methyl-; o-Methylbenzenesulfonamide; ortho-Toluenesulfonamide; 2-Tolylsulfonamide; Ortho-toluol-sulfonamid; ortho-Toluenesulphonamide; DTXSID7021362; R81Z6V889P; NSC-2185; DTXCID301362; o-toluolsulfonamide; RefChem:910086
| Regulatory & Food Contact | FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS |
|---|---|
| GHS notification summary | 65.9% (112 / 170) |
| GHS notification summary | 65.9% (112 / 170) |
|---|---|
| Reported hazard statements | H319 (28.2%), H351 (28.2%) |
This chemical does not meet GHS hazard criteria for 65.9% (112 of 170) of all reports.
H319 (28.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
2-Toluene Sulfonamide · CAS 8013-74-9 · C7H9NO2S. UNII R81Z6V889P. Boiling Point: 214 °C at 10 mm Hg; Boiling Point: >270 °C; Melting Point: 156.3 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 2-甲苯磺酰胺