2-Hydroxy Desipramine

Independent reference data for 2-Hydroxy Desipramine (CAS 1977-15-7), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Documented uses on record

• Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However, the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
• 2-hydroxy-desipramine is a known human metabolite of Desipramine.

Synonyms and trade names

2-Hydroxydesipramine; 1977-15-7; 2-Hydroxydesmethylimipramine; VO1Y07E90C; DTXSID20173467; 2-hydroxy-desipramine; 2-OH-DMI; RefChem:87516; DTXCID6095958; 2-Hydroxy Desipramine; Desipramine Impurity 1; 11-[3-(methylamino)propyl]-5,6-dihydrobenzo[b][1]benzazepin-3-ol; 5-[3-(Methylamino)propyl]-10,11-dihydro-5H-dibenzo[b,f]azepin-2-ol; GP 36329; BRN 5587391; UNII-VO1Y07E90C

What the public record says

2-Hydroxy Desipramine · CAS 1977-15-7 · C18H22N2O. UNII VO1Y07E90C.

Source: PubChem / Wikidata; the batch COA governs where values differ.