2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-4-hydroxy-3-1-sulfo-6-2-(sulfooxy)ethylsulfonyl-2-naphthalenylazo-, tetrasodium salt (CAS 72828-03-6) — formula C19H23N5O3, molecular weight 369.4; category organic chemicals.
| CAS Number | 72828-03-6 |
|---|---|
| Molecular Formula | C19H23N5O3 |
| Molecular Weight | 369.4 |
| Melting Point | 215-217 °C |
| LogP | 2.5 |
| Applications | Uses: MEDICATION, For use, with concurrent leucovorin administration (leucovorin protection), as an alternative therapy for the treatment of moderate-to-severe <i>Pneumocystis carinii<, i> pneumonia (PCP) in immunocompromised patients, including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer., General Manufacturing Information: Lipophilic dihydrofolate reductase structurally related to methotrexate, with antimicrobial and antitumor activity. |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, For use, with concurrent leucovorin administration (leucovorin protection), as an alternative therapy for the treatment of moderate-to-severe <i>Pneumocystis carinii<, i> pneumonia (PCP) in immunocompromised patients, including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer., General Manufacturing Information: Lipophilic dihydrofolate reductase structurally related to methotrexate, with antimicrobial and antitumor activity..
2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-4-hydroxy-3-1-sulfo-6-2-(sulfooxy)ethylsulfonyl-2-naphthalenylazo-, tetrasodium salt is a carbon-based organic compound with CAS registry number 72828-03-6 and molecular formula C19H23N5O3 (molecular weight 369.4), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 72828-03-6
Its molecular formula C19H23N5O3 comprises 19 C, 23 H, 5 N, 3 O atoms.
Also known as: 2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-4-hydroxy-3-1-sulfo-6-2-(sulfooxy)ethylsulfonyl-2-naphthalenylazo-, tetrasodium salt
Category: organic chemicals
The CAS registry number of 2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-4-hydroxy-3-1-sulfo-6-2-(sulfooxy)ethylsulfonyl-2-naphthalenylazo-, tetrasodium salt is 72828-03-6.
Molecular formula C19H23N5O3, molecular weight 369.4.
It is also registered under: 2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-4-hydroxy-3-1-sulfo-6-2-(sulfooxy)ethylsulfonyl-2-naphthalenylazo-, tetrasodium salt.
Recorded applications: Uses: MEDICATION, For use, with concurrent leucovorin administration (leucovorin protection), as an alternative therapy for the treatment of moderate-to-severe <i>Pneumocystis carinii<, i> pneumonia (PCP) in immunocompromised patients, including patients with the acquired immunodeficiency syndrome (AIDS). Also used to treat several types of cancer including colon cancer., General Manufacturing Information: Lipophilic dihydrofolate reductase structurally related to methotrexate, with antimicrobial and antitumor activity..
Category: Organic Chemicals.
Independent reference data for 2,7-Naphthalenedisulfonic acid, 5-(benzoylamino)-4-hydroxy-3-1-sulfo-6-2-(sulfooxy)ethylsulfonyl-2-naphthalenylazo-, tetrasodium salt (CAS 72828-03-6), compiled from public chemistry databases.
| CAS 号 | 72828-03-6 |
|---|---|
| PubChem CID | 5583 |
| 分子式 | C19H23N5O3 |
| IUPAC 名称 | 5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline-2,4-diamine |
| UNII（FDA） | UPN4ITI8T4 |
| Molecular Weight | 369.4 |
|---|---|
| XLogP3 | 2.5 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 6 |
| Exact Mass | 369.18008961 |
| Monoisotopic Mass | 369.18008961 |
| Topological Polar Surface Area | 118 |
| Heavy Atom Count | 27 |
| Melting Point | 215-217 °C |
|---|---|
| Melting Point | 215 - 217 °C |
| Solubility | 31.4 |
| Solubility | 3.09e-02 g/L |
| Solubility | Water 1 - 2 (mg/mL) |
| Solubility | 0.1NHC1 1 - 5 (mg/mL) |
| Solubility | 0.1 N NaOH < 1 (mg/mL) |
| Solubility | Methanol 12 - 15 (mg/mL) |
| Solubility | 95% Ethanol 1 - 5 (mg/mL) |
| Solubility | 10% Ethanol 1 - 3 (mg/mL) |
trimetrexate; 52128-35-5; Trimetrexato; Trimetrexatum; NSC-249008; NSC 249008; UPN4ITI8T4; DTXSID3023714; 5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}quinazoline-2,4-diamine; NSC249008; 2,4-Diamino-5-methyl-6-((3,4,5-trimethoxyanilino)methyl)quinazoline; 5-Methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-2,4-quinazolinediamine; 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)quinazoline-2,4-diamine; 2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-; 5-methyl-6-[[(3,4,5-trimethoxyphenyl)amino]methyl]quinazoline-2,4-diamine; 2,4-diamino-5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazoline
活性红180 · CAS 72828-03-6 · C19H23N5O3. UNII UPN4ITI8T4. Melting Point: 215-217 °C; Melting Point: 215 - 217 °C; Solubility: 31.4.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.