2-(1-Piperazinyl)pyrimidine

Independent reference data for 2-(1-Piperazinyl)pyrimidine (CAS 20980-22-7), compiled from public chemistry databases.

Registry identifiers across databases

Computed descriptors

Physicochemical values on record

Documented uses on record

Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.

Synonyms and trade names

20980-22-7; 2-(Piperazin-1-yl)pyrimidine; 1-(2-Pyrimidinyl)piperazine; Pyrimidine, 2-(1-piperazinyl)-; 1-pyrimidinylpiperazine; H3B5B38F56; DTXSID00864967; MJ-13653; RefChem:422655; DTXCID80208042; 244-135-5; 2-(1-Piperazinyl)pyrimidine; 1-(2-Pyrimidyl)piperazine; 2-piperazin-1-ylpyrimidine; Buspirone EP Impurity A; 2-Piperazino-pyrimidine

GHS hazard classification

Reported hazard statements	H314 (31.3%), H315 (68.7%), H319 (65.7%), H335 (65.7%)

H314 (31.3%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

H315 (68.7%): Causes skin irritation [Warning Skin corrosion/irritation]

What the public record says

2-(1-Piperazinyl)pyrimidine · CAS 20980-22-7 · C8H12N4. UNII H3B5B38F56. LogP: 0.49; Dissociation Constants: 8.9.

Source: PubChem / Wikidata; the batch COA governs where values differ.