10-Propargyl-10-deazaaminopterin (CAS 146464-95-1) — formula C23H23N7O5, molecular weight 477.5; category organic chemicals.
| CAS Number | 146464-95-1 |
|---|---|
| Molecular Formula | C23H23N7O5 |
| Molecular Weight | 477.5 |
| LogP | -0.9 |
| Applications | Uses: MEDICATION, Pralatrexate is indicated for the treatment of ... relapsed or refractory peripheral T-cell lymphoma (PTCL)., Included in US product label, Formulations, Preparations: FOLOTYN (pralatrexate) is available in sterile, single-use vials containing pralatrexate at a concentration of 20 mg, mL in the following presentations: 20 mg of pralatrexate in 1 mL solution in a vial (20 mg, 1 mL), 40 mg of pralatrexate in 2 mL solution in a vial (40 mg, 2 mL). |
| Category | Organic Chemicals |
Documented applications: Uses: MEDICATION, Pralatrexate is indicated for the treatment of ... relapsed or refractory peripheral T-cell lymphoma (PTCL)., Included in US product label, Formulations, Preparations: FOLOTYN (pralatrexate) is available in sterile, single-use vials containing pralatrexate at a concentration of 20 mg, mL in the following presentations: 20 mg of pralatrexate in 1 mL solution in a vial (20 mg, 1 mL), 40 mg of pralatrexate in 2 mL solution in a vial (40 mg, 2 mL)..
10-Propargyl-10-deazaaminopterin is a carbon-based organic compound with CAS registry number 146464-95-1 and molecular formula C23H23N7O5 (molecular weight 477.5), belonging to the organic chemicals segment of chemical raw materials.
CAS number: 146464-95-1
Its molecular formula C23H23N7O5 comprises 23 C, 23 H, 7 N, 5 O atoms.
Also known as: 10-Propargyl-10-deazaaminopterin · 10-炔丙基-10-脱氮氨基蝶呤
Category: organic chemicals
The CAS registry number of 10-Propargyl-10-deazaaminopterin is 146464-95-1.
Molecular formula C23H23N7O5, molecular weight 477.5.
It is also registered under: 10-Propargyl-10-deazaaminopterin, 10-炔丙基-10-脱氮氨基蝶呤.
Recorded applications: Uses: MEDICATION, Pralatrexate is indicated for the treatment of ... relapsed or refractory peripheral T-cell lymphoma (PTCL)., Included in US product label, Formulations, Preparations: FOLOTYN (pralatrexate) is available in sterile, single-use vials containing pralatrexate at a concentration of 20 mg, mL in the following presentations: 20 mg of pralatrexate in 1 mL solution in a vial (20 mg, 1 mL), 40 mg of pralatrexate in 2 mL solution in a vial (40 mg, 2 mL)..
Category: Organic Chemicals.
Independent reference data for 10-Propargyl-10-deazaaminopterin (CAS 146464-95-1), compiled from public chemistry databases.
| CAS Registry Number | 146464-95-1 |
|---|---|
| PubChem CID | 148121 |
| Molecular formula | C23H23N7O5 |
| IUPAC name | (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid |
| UNII (FDA) | A8Q8I19Q20 |
| Molecular Weight | 477.5 |
|---|---|
| XLogP3 | -0.9 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 11 |
| Rotatable Bond Count | 10 |
| Exact Mass | 477.17606686 |
| Monoisotopic Mass | 477.17606686 |
| Topological Polar Surface Area | 207 |
| Heavy Atom Count | 35 |
Pralatrexate; 146464-95-1; Folotyn; 10-Propargyl-10-deazaaminopterin; pralatrexato; HSDB 7786; N-(4-(1-((2,4-Diamino-6-pteridinyl)methyl)-3-butynyl)benzoyl)-L-glutamic acid; pralatrexatum; DTXSID3048578; NSC-754230; CHEBI:71223; A8Q8I19Q20; (2S)-2-((4-((1RS)-1-((2,4-Diaminopteridin-6-yl)methyl)but-3-ynyl)benzoyl)amino)pentanedioic acid; (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid; DTXCID3028504; N-{4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl}-L-glutamic acid
| Reported hazard statements | H301 (66.7%), H311 (16.7%), H315 (33.3%), H319 (16.7%), H331 (16.7%), H335 (16.7%), H340 (16.7%), H351 (16.7%) |
|---|
H301 (66.7%): Toxic if swallowed [Danger Acute toxicity, oral]
H311 (16.7%): Toxic in contact with skin [Danger Acute toxicity, dermal]
10-Propargyl-10-deazaaminopterin · CAS 146464-95-1 · C23H23N7O5. UNII A8Q8I19Q20.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 10-炔丙基-10-脱氮氨基蝶呤